Gut Microbiota Alterations from Three-Strain Yogurt Formulation Treatments in Slow-Transit Constipation
The objective of this study was to evaluate the effects of a three-strain yogurt formulation in slow-transit constipation (STC) patients. Each individual in both treatment groups consumed 250 mL of the formulated yogurt daily for a week (7 days), and fecal samples were collected for gut microbiota a...
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| Format: | Article |
| Language: | English |
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Wiley
2020-01-01
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| Series: | Canadian Journal of Infectious Diseases and Medical Microbiology |
| Online Access: | http://dx.doi.org/10.1155/2020/4583973 |
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| author | Xiao-Ran Li Chen-Jian Liu Xiao-Dan Tang He-Ming Zhang Yi-Yong Luo Le Zhang En yang |
| author_facet | Xiao-Ran Li Chen-Jian Liu Xiao-Dan Tang He-Ming Zhang Yi-Yong Luo Le Zhang En yang |
| author_sort | Xiao-Ran Li |
| collection | DOAJ |
| description | The objective of this study was to evaluate the effects of a three-strain yogurt formulation in slow-transit constipation (STC) patients. Each individual in both treatment groups consumed 250 mL of the formulated yogurt daily for a week (7 days), and fecal samples were collected for gut microbiota and short-chain fatty acid (SCFA) analyses. A significant increase in the defection frequency (p<0.001) and bacterial diversity (p=0.027) at the 100% sequence homology level and a decrease in the concentrations of acetic acid (p=0.014), propionic acid (p=0.019), and butanoic acid (p=0.005) were observed after the STC patients consumed three-strain yogurt formulation. In addition, the consumption of the three-strain yogurt formulation significantly altered the composition of the intestinal bacteria in the STC patients. The relative abundances of 23 genera in the top dominating genera were altered significantly after the STC patients consumed the yogurt. In summary, the consumption of 250 mL day− the three-strain yogurt formulation described in this study can play a role in improving the symptoms of STC. |
| format | Article |
| id | doaj-art-62834c80a8bc4d358bbd6c6b90b741c3 |
| institution | Kabale University |
| issn | 1712-9532 1918-1493 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Canadian Journal of Infectious Diseases and Medical Microbiology |
| spelling | doaj-art-62834c80a8bc4d358bbd6c6b90b741c32025-02-03T06:06:38ZengWileyCanadian Journal of Infectious Diseases and Medical Microbiology1712-95321918-14932020-01-01202010.1155/2020/45839734583973Gut Microbiota Alterations from Three-Strain Yogurt Formulation Treatments in Slow-Transit ConstipationXiao-Ran Li0Chen-Jian Liu1Xiao-Dan Tang2He-Ming Zhang3Yi-Yong Luo4Le Zhang5En yang6Faculty of Life Science and Technology, Kunming University of Science and Technology, Chenggong, Kunming 650500, Yunnan, ChinaFaculty of Life Science and Technology, Kunming University of Science and Technology, Chenggong, Kunming 650500, Yunnan, ChinaDepartment of Gastroenterology, First People Hospital of Yunnan Province, Kunming 650032, Yunnan, ChinaDepartment of Gastroenterology, First People Hospital of Yunnan Province, Kunming 650032, Yunnan, ChinaFaculty of Life Science and Technology, Kunming University of Science and Technology, Chenggong, Kunming 650500, Yunnan, ChinaInstitute for Integrative Genome Biology, University of California Riverside, Riverside, CA 92521, USAFaculty of Life Science and Technology, Kunming University of Science and Technology, Chenggong, Kunming 650500, Yunnan, ChinaThe objective of this study was to evaluate the effects of a three-strain yogurt formulation in slow-transit constipation (STC) patients. Each individual in both treatment groups consumed 250 mL of the formulated yogurt daily for a week (7 days), and fecal samples were collected for gut microbiota and short-chain fatty acid (SCFA) analyses. A significant increase in the defection frequency (p<0.001) and bacterial diversity (p=0.027) at the 100% sequence homology level and a decrease in the concentrations of acetic acid (p=0.014), propionic acid (p=0.019), and butanoic acid (p=0.005) were observed after the STC patients consumed three-strain yogurt formulation. In addition, the consumption of the three-strain yogurt formulation significantly altered the composition of the intestinal bacteria in the STC patients. The relative abundances of 23 genera in the top dominating genera were altered significantly after the STC patients consumed the yogurt. In summary, the consumption of 250 mL day− the three-strain yogurt formulation described in this study can play a role in improving the symptoms of STC.http://dx.doi.org/10.1155/2020/4583973 |
| spellingShingle | Xiao-Ran Li Chen-Jian Liu Xiao-Dan Tang He-Ming Zhang Yi-Yong Luo Le Zhang En yang Gut Microbiota Alterations from Three-Strain Yogurt Formulation Treatments in Slow-Transit Constipation Canadian Journal of Infectious Diseases and Medical Microbiology |
| title | Gut Microbiota Alterations from Three-Strain Yogurt Formulation Treatments in Slow-Transit Constipation |
| title_full | Gut Microbiota Alterations from Three-Strain Yogurt Formulation Treatments in Slow-Transit Constipation |
| title_fullStr | Gut Microbiota Alterations from Three-Strain Yogurt Formulation Treatments in Slow-Transit Constipation |
| title_full_unstemmed | Gut Microbiota Alterations from Three-Strain Yogurt Formulation Treatments in Slow-Transit Constipation |
| title_short | Gut Microbiota Alterations from Three-Strain Yogurt Formulation Treatments in Slow-Transit Constipation |
| title_sort | gut microbiota alterations from three strain yogurt formulation treatments in slow transit constipation |
| url | http://dx.doi.org/10.1155/2020/4583973 |
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