The Anticancer Perspective of Tangeretin: A Small Review
Cancer is an important disease that threatens human life and health. Many natural compounds from plants have been found to have a better inhibitory effect on cancer, and flavonoids are one of them. Tangeretin, a flavonoid, is widely present in a variety of citrus plants and has been shown to have a...
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MDPI AG
2025-01-01
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| Series: | Molecules |
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| author | Yuan Xu Xi Yan Junpeng Zhuang Haijun Hao |
| author_facet | Yuan Xu Xi Yan Junpeng Zhuang Haijun Hao |
| author_sort | Yuan Xu |
| collection | DOAJ |
| description | Cancer is an important disease that threatens human life and health. Many natural compounds from plants have been found to have a better inhibitory effect on cancer, and flavonoids are one of them. Tangeretin, a flavonoid, is widely present in a variety of citrus plants and has been shown to have a variety of biological activities that can inhibit tumor cells. Tangeretin can inhibit the growth, proliferation, and metastasis of cancer cells by acting on JAK/STAT (Janus Kinase/signal transducer and activator of transcription) and caspase-3 signal transduction and by regulating the cell cycle of tumor cells. Tangeretin can also work with other chemotherapy drugs, such as cisplatin, to reduce the drug resistance of cancer cells and improve the therapeutic effect of chemotherapy drugs. This review summarizes the effects of tangeretin on various cancers. |
| format | Article |
| id | doaj-art-62538dc3320248db9dc55fa96c3e74f6 |
| institution | Kabale University |
| issn | 1420-3049 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj-art-62538dc3320248db9dc55fa96c3e74f62025-01-24T13:43:29ZengMDPI AGMolecules1420-30492025-01-0130230010.3390/molecules30020300The Anticancer Perspective of Tangeretin: A Small ReviewYuan Xu0Xi Yan1Junpeng Zhuang2Haijun Hao3Department of Organic Chemistry, College of Chemistry, Beijing University of Chemical Technology, Beijing 100029, ChinaCollege of Chemistry, Beijing Normal University, Beijing 100875, ChinaDepartment of Organic Chemistry, College of Chemistry, Beijing University of Chemical Technology, Beijing 100029, ChinaDepartment of Organic Chemistry, College of Chemistry, Beijing University of Chemical Technology, Beijing 100029, ChinaCancer is an important disease that threatens human life and health. Many natural compounds from plants have been found to have a better inhibitory effect on cancer, and flavonoids are one of them. Tangeretin, a flavonoid, is widely present in a variety of citrus plants and has been shown to have a variety of biological activities that can inhibit tumor cells. Tangeretin can inhibit the growth, proliferation, and metastasis of cancer cells by acting on JAK/STAT (Janus Kinase/signal transducer and activator of transcription) and caspase-3 signal transduction and by regulating the cell cycle of tumor cells. Tangeretin can also work with other chemotherapy drugs, such as cisplatin, to reduce the drug resistance of cancer cells and improve the therapeutic effect of chemotherapy drugs. This review summarizes the effects of tangeretin on various cancers.https://www.mdpi.com/1420-3049/30/2/300flavonoidstangeretinbiological activityanticancer substancechemotherapynatural compounds |
| spellingShingle | Yuan Xu Xi Yan Junpeng Zhuang Haijun Hao The Anticancer Perspective of Tangeretin: A Small Review Molecules flavonoids tangeretin biological activity anticancer substance chemotherapy natural compounds |
| title | The Anticancer Perspective of Tangeretin: A Small Review |
| title_full | The Anticancer Perspective of Tangeretin: A Small Review |
| title_fullStr | The Anticancer Perspective of Tangeretin: A Small Review |
| title_full_unstemmed | The Anticancer Perspective of Tangeretin: A Small Review |
| title_short | The Anticancer Perspective of Tangeretin: A Small Review |
| title_sort | anticancer perspective of tangeretin a small review |
| topic | flavonoids tangeretin biological activity anticancer substance chemotherapy natural compounds |
| url | https://www.mdpi.com/1420-3049/30/2/300 |
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