Bigeminy with Prolonged QT Interval as an Ominous Sign for Impending Torsades de Pointes: A Case Report

Introduction: Ventricular ectopic beats and corrected QT interval (QTc) prolongation are both relatively common entities that are typically benign. It is difficult to predict subsequent dysrhythmias from either electrocardiogram (ECG) feature. The combination of both features may better predict the...

Full description

Saved in:
Bibliographic Details
Main Authors: Thuc Vu, Jake Valentine
Format: Article
Language:English
Published: eScholarship Publishing, University of California 2024-11-01
Series:Clinical Practice and Cases in Emergency Medicine
Online Access:https://escholarship.org/uc/item/8gg22611
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832540600226807808
author Thuc Vu
Jake Valentine
author_facet Thuc Vu
Jake Valentine
author_sort Thuc Vu
collection DOAJ
description Introduction: Ventricular ectopic beats and corrected QT interval (QTc) prolongation are both relatively common entities that are typically benign. It is difficult to predict subsequent dysrhythmias from either electrocardiogram (ECG) feature. The combination of both features may better predict the risk of torsades de pointes. We highlight a case of torsades preceded by a bizarre bigeminal rhythm with QTc prolongation likely caused by memantine use and hypokalemia. Case Report: An 84-year-old female presented to the emergency department with a fall. A syncope workup revealed an ECG demonstrating bigeminy with a prolonged QTc interval. Several minutes after obtaining the ECG, the patient went into torsades. She had multiple subsequent cardiac arrests during the rest of her hospital stay. This case report details the importance of recognizing ventricular bigeminy in the context of QTc prolongation as a harbinger of torsades. Conclusion: While premature ventricular contractions including bigeminy may be a benign finding, when accompanied by prolonged QTc intervals, they warrant immediate investigation and treatment of potential underlying pathology to prevent torsades and subsequent cardiac arrest.
format Article
id doaj-art-624c74f8322d4a568e72504feda37096
institution Kabale University
issn 2474-252X
language English
publishDate 2024-11-01
publisher eScholarship Publishing, University of California
record_format Article
series Clinical Practice and Cases in Emergency Medicine
spelling doaj-art-624c74f8322d4a568e72504feda370962025-02-04T17:35:19ZengeScholarship Publishing, University of CaliforniaClinical Practice and Cases in Emergency Medicine2474-252X2024-11-0191576010.5811/cpcem.19484cpcem-9-57Bigeminy with Prolonged QT Interval as an Ominous Sign for Impending Torsades de Pointes: A Case ReportThuc Vu0Jake Valentine1Kansas City University College of Osteopathic Medicine, Kansas City, MissouriUniversity of Houston Tilman J. Fertitta Family College of Medicine, Houston, TexasIntroduction: Ventricular ectopic beats and corrected QT interval (QTc) prolongation are both relatively common entities that are typically benign. It is difficult to predict subsequent dysrhythmias from either electrocardiogram (ECG) feature. The combination of both features may better predict the risk of torsades de pointes. We highlight a case of torsades preceded by a bizarre bigeminal rhythm with QTc prolongation likely caused by memantine use and hypokalemia. Case Report: An 84-year-old female presented to the emergency department with a fall. A syncope workup revealed an ECG demonstrating bigeminy with a prolonged QTc interval. Several minutes after obtaining the ECG, the patient went into torsades. She had multiple subsequent cardiac arrests during the rest of her hospital stay. This case report details the importance of recognizing ventricular bigeminy in the context of QTc prolongation as a harbinger of torsades. Conclusion: While premature ventricular contractions including bigeminy may be a benign finding, when accompanied by prolonged QTc intervals, they warrant immediate investigation and treatment of potential underlying pathology to prevent torsades and subsequent cardiac arrest.https://escholarship.org/uc/item/8gg22611
spellingShingle Thuc Vu
Jake Valentine
Bigeminy with Prolonged QT Interval as an Ominous Sign for Impending Torsades de Pointes: A Case Report
Clinical Practice and Cases in Emergency Medicine
title Bigeminy with Prolonged QT Interval as an Ominous Sign for Impending Torsades de Pointes: A Case Report
title_full Bigeminy with Prolonged QT Interval as an Ominous Sign for Impending Torsades de Pointes: A Case Report
title_fullStr Bigeminy with Prolonged QT Interval as an Ominous Sign for Impending Torsades de Pointes: A Case Report
title_full_unstemmed Bigeminy with Prolonged QT Interval as an Ominous Sign for Impending Torsades de Pointes: A Case Report
title_short Bigeminy with Prolonged QT Interval as an Ominous Sign for Impending Torsades de Pointes: A Case Report
title_sort bigeminy with prolonged qt interval as an ominous sign for impending torsades de pointes a case report
url https://escholarship.org/uc/item/8gg22611
work_keys_str_mv AT thucvu bigeminywithprolongedqtintervalasanominoussignforimpendingtorsadesdepointesacasereport
AT jakevalentine bigeminywithprolongedqtintervalasanominoussignforimpendingtorsadesdepointesacasereport