Low Reactive Level Laser Therapy for Mesenchymal Stromal Cells Therapies
Low reactive level laser therapy (LLLT) is mainly focused on the activation of intracellular or extracellular chromophore and the initiation of cellular signaling by using low power lasers. Over the past forty years, it was realized that the laser therapy had the potential to improve wound healing a...
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| Format: | Article |
| Language: | English |
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Wiley
2015-01-01
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| Series: | Stem Cells International |
| Online Access: | http://dx.doi.org/10.1155/2015/974864 |
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| _version_ | 1832555469118373888 |
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| author | Toshihiro Kushibiki Takeshi Hirasawa Shinpei Okawa Miya Ishihara |
| author_facet | Toshihiro Kushibiki Takeshi Hirasawa Shinpei Okawa Miya Ishihara |
| author_sort | Toshihiro Kushibiki |
| collection | DOAJ |
| description | Low reactive level laser therapy (LLLT) is mainly focused on the activation of intracellular or extracellular chromophore and the initiation of cellular signaling by using low power lasers. Over the past forty years, it was realized that the laser therapy had the potential to improve wound healing and reduce pain and inflammation. In recent years, the term LLLT has become widely recognized in the field of regenerative medicine. In this review, we will describe the mechanisms of action of LLLT at a cellular level and introduce the application to mesenchymal stem cells and mesenchymal stromal cells (MSCs) therapies. Finally, our recent research results that LLLT enhanced the MSCs differentiation to osteoblast will also be described. |
| format | Article |
| id | doaj-art-6240d2dbf5e94a8da49dcd87b105d26d |
| institution | Kabale University |
| issn | 1687-966X 1687-9678 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Stem Cells International |
| spelling | doaj-art-6240d2dbf5e94a8da49dcd87b105d26d2025-02-03T05:48:08ZengWileyStem Cells International1687-966X1687-96782015-01-01201510.1155/2015/974864974864Low Reactive Level Laser Therapy for Mesenchymal Stromal Cells TherapiesToshihiro Kushibiki0Takeshi Hirasawa1Shinpei Okawa2Miya Ishihara3Department of Medical Engineering, National Defense Medical College, 3-2 Namiki, Tokorozawa, Saitama 359-8513, JapanDepartment of Medical Engineering, National Defense Medical College, 3-2 Namiki, Tokorozawa, Saitama 359-8513, JapanDepartment of Medical Engineering, National Defense Medical College, 3-2 Namiki, Tokorozawa, Saitama 359-8513, JapanDepartment of Medical Engineering, National Defense Medical College, 3-2 Namiki, Tokorozawa, Saitama 359-8513, JapanLow reactive level laser therapy (LLLT) is mainly focused on the activation of intracellular or extracellular chromophore and the initiation of cellular signaling by using low power lasers. Over the past forty years, it was realized that the laser therapy had the potential to improve wound healing and reduce pain and inflammation. In recent years, the term LLLT has become widely recognized in the field of regenerative medicine. In this review, we will describe the mechanisms of action of LLLT at a cellular level and introduce the application to mesenchymal stem cells and mesenchymal stromal cells (MSCs) therapies. Finally, our recent research results that LLLT enhanced the MSCs differentiation to osteoblast will also be described.http://dx.doi.org/10.1155/2015/974864 |
| spellingShingle | Toshihiro Kushibiki Takeshi Hirasawa Shinpei Okawa Miya Ishihara Low Reactive Level Laser Therapy for Mesenchymal Stromal Cells Therapies Stem Cells International |
| title | Low Reactive Level Laser Therapy for Mesenchymal Stromal Cells Therapies |
| title_full | Low Reactive Level Laser Therapy for Mesenchymal Stromal Cells Therapies |
| title_fullStr | Low Reactive Level Laser Therapy for Mesenchymal Stromal Cells Therapies |
| title_full_unstemmed | Low Reactive Level Laser Therapy for Mesenchymal Stromal Cells Therapies |
| title_short | Low Reactive Level Laser Therapy for Mesenchymal Stromal Cells Therapies |
| title_sort | low reactive level laser therapy for mesenchymal stromal cells therapies |
| url | http://dx.doi.org/10.1155/2015/974864 |
| work_keys_str_mv | AT toshihirokushibiki lowreactivelevellasertherapyformesenchymalstromalcellstherapies AT takeshihirasawa lowreactivelevellasertherapyformesenchymalstromalcellstherapies AT shinpeiokawa lowreactivelevellasertherapyformesenchymalstromalcellstherapies AT miyaishihara lowreactivelevellasertherapyformesenchymalstromalcellstherapies |