A critical assessment of ionic liquid-based aqueous biphasic systems for biomolecules extraction and CO2 absorption

Ionic liquids (ILs) are green designer solvents that have gained research interest in industrial applications, including solvent chemistry, catalysis, and electrochemistry. Recent advances in ionic liquid-based aqueous biphasic systems (IL-ABSs) have broadened their biological applications. This rev...

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Main Authors: Viggy Wee Gee Tan, Yazan Abuhasheesh, Doris Ying Ying Tang, Yongyu Zhang, Zengling Ma, Lin Chen, Rambabu Krishnamoorthy, Pau Loke Show
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Chemical Engineering Journal Advances
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Online Access:http://www.sciencedirect.com/science/article/pii/S2666821124000875
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author Viggy Wee Gee Tan
Yazan Abuhasheesh
Doris Ying Ying Tang
Yongyu Zhang
Zengling Ma
Lin Chen
Rambabu Krishnamoorthy
Pau Loke Show
author_facet Viggy Wee Gee Tan
Yazan Abuhasheesh
Doris Ying Ying Tang
Yongyu Zhang
Zengling Ma
Lin Chen
Rambabu Krishnamoorthy
Pau Loke Show
author_sort Viggy Wee Gee Tan
collection DOAJ
description Ionic liquids (ILs) are green designer solvents that have gained research interest in industrial applications, including solvent chemistry, catalysis, and electrochemistry. Recent advances in ionic liquid-based aqueous biphasic systems (IL-ABSs) have broadened their biological applications. This review discusses the state-of-the-art of its biotechnological application in biomolecules recovery and phase separation mechanism. The prospects of ILs as green solvents and their toxicity and applicability in carbon dioxide (CO2) capture are discussed. The correlation between the structures and toxicity of ILs is also provided, with a special emphasis on the synthesis of safer ILs. This review examines the significance and techniques in recovering and reusing phase-forming agents such as ILs. The incorporation of machine learning (ML) algorithms to predict the toxicity and CO2 capture properties, as well as the scaling up of IL-ABSs, is also explored.
format Article
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institution Kabale University
issn 2666-8211
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publishDate 2025-03-01
publisher Elsevier
record_format Article
series Chemical Engineering Journal Advances
spelling doaj-art-6229251617c34f9f89e88765f4ab337e2025-02-03T04:16:59ZengElsevierChemical Engineering Journal Advances2666-82112025-03-0121100670A critical assessment of ionic liquid-based aqueous biphasic systems for biomolecules extraction and CO2 absorptionViggy Wee Gee Tan0Yazan Abuhasheesh1Doris Ying Ying Tang2Yongyu Zhang3Zengling Ma4Lin Chen5Rambabu Krishnamoorthy6Pau Loke Show7Department of Chemical and Environmental Engineering, University of Nottingham Malaysia, Broga Road, 43500, Semenyih, Selangor Darul Ehsan, MalaysiaDepartment of Chemical & Petroleum Engineering, Khalifa University, PO Box 127788, Abu Dhabi, United Arab EmiratesDepartment of Chemical & Petroleum Engineering, Khalifa University, PO Box 127788, Abu Dhabi, United Arab EmiratesQingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao, ChinaNational and Local Joint Engineering Research Center of Ecological Treatment Technology for Urban Water Pollution, Wenzhou University, Wenzhou 325035, China; Corresponding author.Institute of Sericultural and Tea, Zhejiang Academy of Agricultural Sciences, Hangzhou, Zhejiang 310021, ChinaDepartment of Chemical & Petroleum Engineering, Khalifa University, PO Box 127788, Abu Dhabi, United Arab EmiratesDepartment of Chemical & Petroleum Engineering, Khalifa University, PO Box 127788, Abu Dhabi, United Arab Emirates; Corresponding author.Ionic liquids (ILs) are green designer solvents that have gained research interest in industrial applications, including solvent chemistry, catalysis, and electrochemistry. Recent advances in ionic liquid-based aqueous biphasic systems (IL-ABSs) have broadened their biological applications. This review discusses the state-of-the-art of its biotechnological application in biomolecules recovery and phase separation mechanism. The prospects of ILs as green solvents and their toxicity and applicability in carbon dioxide (CO2) capture are discussed. The correlation between the structures and toxicity of ILs is also provided, with a special emphasis on the synthesis of safer ILs. This review examines the significance and techniques in recovering and reusing phase-forming agents such as ILs. The incorporation of machine learning (ML) algorithms to predict the toxicity and CO2 capture properties, as well as the scaling up of IL-ABSs, is also explored.http://www.sciencedirect.com/science/article/pii/S2666821124000875Ionic liquidsBioactive compoundsMachine learningSeparationCO2 capture
spellingShingle Viggy Wee Gee Tan
Yazan Abuhasheesh
Doris Ying Ying Tang
Yongyu Zhang
Zengling Ma
Lin Chen
Rambabu Krishnamoorthy
Pau Loke Show
A critical assessment of ionic liquid-based aqueous biphasic systems for biomolecules extraction and CO2 absorption
Chemical Engineering Journal Advances
Ionic liquids
Bioactive compounds
Machine learning
Separation
CO2 capture
title A critical assessment of ionic liquid-based aqueous biphasic systems for biomolecules extraction and CO2 absorption
title_full A critical assessment of ionic liquid-based aqueous biphasic systems for biomolecules extraction and CO2 absorption
title_fullStr A critical assessment of ionic liquid-based aqueous biphasic systems for biomolecules extraction and CO2 absorption
title_full_unstemmed A critical assessment of ionic liquid-based aqueous biphasic systems for biomolecules extraction and CO2 absorption
title_short A critical assessment of ionic liquid-based aqueous biphasic systems for biomolecules extraction and CO2 absorption
title_sort critical assessment of ionic liquid based aqueous biphasic systems for biomolecules extraction and co2 absorption
topic Ionic liquids
Bioactive compounds
Machine learning
Separation
CO2 capture
url http://www.sciencedirect.com/science/article/pii/S2666821124000875
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