A critical assessment of ionic liquid-based aqueous biphasic systems for biomolecules extraction and CO2 absorption
Ionic liquids (ILs) are green designer solvents that have gained research interest in industrial applications, including solvent chemistry, catalysis, and electrochemistry. Recent advances in ionic liquid-based aqueous biphasic systems (IL-ABSs) have broadened their biological applications. This rev...
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Elsevier
2025-03-01
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author | Viggy Wee Gee Tan Yazan Abuhasheesh Doris Ying Ying Tang Yongyu Zhang Zengling Ma Lin Chen Rambabu Krishnamoorthy Pau Loke Show |
author_facet | Viggy Wee Gee Tan Yazan Abuhasheesh Doris Ying Ying Tang Yongyu Zhang Zengling Ma Lin Chen Rambabu Krishnamoorthy Pau Loke Show |
author_sort | Viggy Wee Gee Tan |
collection | DOAJ |
description | Ionic liquids (ILs) are green designer solvents that have gained research interest in industrial applications, including solvent chemistry, catalysis, and electrochemistry. Recent advances in ionic liquid-based aqueous biphasic systems (IL-ABSs) have broadened their biological applications. This review discusses the state-of-the-art of its biotechnological application in biomolecules recovery and phase separation mechanism. The prospects of ILs as green solvents and their toxicity and applicability in carbon dioxide (CO2) capture are discussed. The correlation between the structures and toxicity of ILs is also provided, with a special emphasis on the synthesis of safer ILs. This review examines the significance and techniques in recovering and reusing phase-forming agents such as ILs. The incorporation of machine learning (ML) algorithms to predict the toxicity and CO2 capture properties, as well as the scaling up of IL-ABSs, is also explored. |
format | Article |
id | doaj-art-6229251617c34f9f89e88765f4ab337e |
institution | Kabale University |
issn | 2666-8211 |
language | English |
publishDate | 2025-03-01 |
publisher | Elsevier |
record_format | Article |
series | Chemical Engineering Journal Advances |
spelling | doaj-art-6229251617c34f9f89e88765f4ab337e2025-02-03T04:16:59ZengElsevierChemical Engineering Journal Advances2666-82112025-03-0121100670A critical assessment of ionic liquid-based aqueous biphasic systems for biomolecules extraction and CO2 absorptionViggy Wee Gee Tan0Yazan Abuhasheesh1Doris Ying Ying Tang2Yongyu Zhang3Zengling Ma4Lin Chen5Rambabu Krishnamoorthy6Pau Loke Show7Department of Chemical and Environmental Engineering, University of Nottingham Malaysia, Broga Road, 43500, Semenyih, Selangor Darul Ehsan, MalaysiaDepartment of Chemical & Petroleum Engineering, Khalifa University, PO Box 127788, Abu Dhabi, United Arab EmiratesDepartment of Chemical & Petroleum Engineering, Khalifa University, PO Box 127788, Abu Dhabi, United Arab EmiratesQingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao, ChinaNational and Local Joint Engineering Research Center of Ecological Treatment Technology for Urban Water Pollution, Wenzhou University, Wenzhou 325035, China; Corresponding author.Institute of Sericultural and Tea, Zhejiang Academy of Agricultural Sciences, Hangzhou, Zhejiang 310021, ChinaDepartment of Chemical & Petroleum Engineering, Khalifa University, PO Box 127788, Abu Dhabi, United Arab EmiratesDepartment of Chemical & Petroleum Engineering, Khalifa University, PO Box 127788, Abu Dhabi, United Arab Emirates; Corresponding author.Ionic liquids (ILs) are green designer solvents that have gained research interest in industrial applications, including solvent chemistry, catalysis, and electrochemistry. Recent advances in ionic liquid-based aqueous biphasic systems (IL-ABSs) have broadened their biological applications. This review discusses the state-of-the-art of its biotechnological application in biomolecules recovery and phase separation mechanism. The prospects of ILs as green solvents and their toxicity and applicability in carbon dioxide (CO2) capture are discussed. The correlation between the structures and toxicity of ILs is also provided, with a special emphasis on the synthesis of safer ILs. This review examines the significance and techniques in recovering and reusing phase-forming agents such as ILs. The incorporation of machine learning (ML) algorithms to predict the toxicity and CO2 capture properties, as well as the scaling up of IL-ABSs, is also explored.http://www.sciencedirect.com/science/article/pii/S2666821124000875Ionic liquidsBioactive compoundsMachine learningSeparationCO2 capture |
spellingShingle | Viggy Wee Gee Tan Yazan Abuhasheesh Doris Ying Ying Tang Yongyu Zhang Zengling Ma Lin Chen Rambabu Krishnamoorthy Pau Loke Show A critical assessment of ionic liquid-based aqueous biphasic systems for biomolecules extraction and CO2 absorption Chemical Engineering Journal Advances Ionic liquids Bioactive compounds Machine learning Separation CO2 capture |
title | A critical assessment of ionic liquid-based aqueous biphasic systems for biomolecules extraction and CO2 absorption |
title_full | A critical assessment of ionic liquid-based aqueous biphasic systems for biomolecules extraction and CO2 absorption |
title_fullStr | A critical assessment of ionic liquid-based aqueous biphasic systems for biomolecules extraction and CO2 absorption |
title_full_unstemmed | A critical assessment of ionic liquid-based aqueous biphasic systems for biomolecules extraction and CO2 absorption |
title_short | A critical assessment of ionic liquid-based aqueous biphasic systems for biomolecules extraction and CO2 absorption |
title_sort | critical assessment of ionic liquid based aqueous biphasic systems for biomolecules extraction and co2 absorption |
topic | Ionic liquids Bioactive compounds Machine learning Separation CO2 capture |
url | http://www.sciencedirect.com/science/article/pii/S2666821124000875 |
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