A Case of Congenital Syphilis Presenting with Unusual Skin Eruptions

Once believed to be a rare disease in developed countries, recent data suggest that there is a surge in incidence of congenital syphilis in many developed countries. Diagnosis of congenital syphilis can be difficult because more than two-thirds of affected infants are asymptomatic at birth, and sign...

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Main Authors: Alexander K. C. Leung, Kin Fon Leong, Joseph M. Lam
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Case Reports in Pediatrics
Online Access:http://dx.doi.org/10.1155/2018/1761454
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author Alexander K. C. Leung
Kin Fon Leong
Joseph M. Lam
author_facet Alexander K. C. Leung
Kin Fon Leong
Joseph M. Lam
author_sort Alexander K. C. Leung
collection DOAJ
description Once believed to be a rare disease in developed countries, recent data suggest that there is a surge in incidence of congenital syphilis in many developed countries. Diagnosis of congenital syphilis can be difficult because more than two-thirds of affected infants are asymptomatic at birth, and signs of symptomatic infants may be nonspecific or subtle. On top of this, some affected infants may have atypical presentations. Familiarity with the diverse presentations is essential to diagnosis. We report a 2-week-old male infant with congenital syphilis whose cutaneous manifestations included diffuse, erythematous keratoderma with desquamation and fissures on his hands and feet, multiple linear scaly fissures at the angles of his mouth, and onychauxis of the fingernails and toenails To our knowledge, diffuse, erythematous keratoderma of the hands and feet and thick nails have not been reported previously in congenital syphilis.
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spelling doaj-art-621780284ba549939b4842428e6bb6702025-02-03T05:51:55ZengWileyCase Reports in Pediatrics2090-68032090-68112018-01-01201810.1155/2018/17614541761454A Case of Congenital Syphilis Presenting with Unusual Skin EruptionsAlexander K. C. Leung0Kin Fon Leong1Joseph M. Lam2Department of Pediatrics, Alberta Children’s Hospital, University of Calgary, Calgary, AB, T2M 0H5, CanadaPediatric Institute, Kuala Lumpur General Hospital, Kuala Lumpur, MalaysiaDepartment of Pediatrics, Department of Dermatology and Skin Sciences, University of British Columbia, Vancouver, BC, V5Z 1K1, CanadaOnce believed to be a rare disease in developed countries, recent data suggest that there is a surge in incidence of congenital syphilis in many developed countries. Diagnosis of congenital syphilis can be difficult because more than two-thirds of affected infants are asymptomatic at birth, and signs of symptomatic infants may be nonspecific or subtle. On top of this, some affected infants may have atypical presentations. Familiarity with the diverse presentations is essential to diagnosis. We report a 2-week-old male infant with congenital syphilis whose cutaneous manifestations included diffuse, erythematous keratoderma with desquamation and fissures on his hands and feet, multiple linear scaly fissures at the angles of his mouth, and onychauxis of the fingernails and toenails To our knowledge, diffuse, erythematous keratoderma of the hands and feet and thick nails have not been reported previously in congenital syphilis.http://dx.doi.org/10.1155/2018/1761454
spellingShingle Alexander K. C. Leung
Kin Fon Leong
Joseph M. Lam
A Case of Congenital Syphilis Presenting with Unusual Skin Eruptions
Case Reports in Pediatrics
title A Case of Congenital Syphilis Presenting with Unusual Skin Eruptions
title_full A Case of Congenital Syphilis Presenting with Unusual Skin Eruptions
title_fullStr A Case of Congenital Syphilis Presenting with Unusual Skin Eruptions
title_full_unstemmed A Case of Congenital Syphilis Presenting with Unusual Skin Eruptions
title_short A Case of Congenital Syphilis Presenting with Unusual Skin Eruptions
title_sort case of congenital syphilis presenting with unusual skin eruptions
url http://dx.doi.org/10.1155/2018/1761454
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