Use of Fourier-Domain Optical Coherence Tomography to Evaluate Anterior Stromal Opacities in Donor Corneas

Purpose. To evaluate Fourier-domain optical coherence tomography (FD-OCT) as an adjunct to traditional slit lamp examination of donor corneas with suspected Anterior Stromal Opacities. Methods. Seven corneas suspected of having anterior stromal opacities by slit lamp examination were evaluated with...

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Main Authors: Matthew R. Bald, Christopher Stoeger, Joshua Galloway, Maolong Tang, Jeffrey Holiman, David Huang
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Journal of Ophthalmology
Online Access:http://dx.doi.org/10.1155/2013/397680
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author Matthew R. Bald
Christopher Stoeger
Joshua Galloway
Maolong Tang
Jeffrey Holiman
David Huang
author_facet Matthew R. Bald
Christopher Stoeger
Joshua Galloway
Maolong Tang
Jeffrey Holiman
David Huang
author_sort Matthew R. Bald
collection DOAJ
description Purpose. To evaluate Fourier-domain optical coherence tomography (FD-OCT) as an adjunct to traditional slit lamp examination of donor corneas with suspected Anterior Stromal Opacities. Methods. Seven corneas suspected of having anterior stromal opacities by slit lamp examination were evaluated with FD-OCT. Each cornea was evaluated to confirm the presence of opacity and, if present, the depth of opacity was measured. Results. The opacity depth ranged from 82 μm to 624 μm. The initial slit lamp impressions of five of the seven corneas were confirmed by OCT. In two corneas, the OCT findings were different from the initial slit lamp impressions. Slit lamp examination of the first cornea gave the impression of anterior stromal scarring, but OCT showed that the opacity was limited to the epithelium. Slit lamp examination of the second cornea suggested opacity limited to the epithelium, but OCT identified significant sub-Bowman's scarring. In all cases, the Eye Bank Technicians reported that the location and depth of corneal opacity were more sharply defined by OCT than by slit lamp. Conclusion. The high resolution of OCT makes it easier to determine the location of corneal opacities compared to slit lamp examinations. This enhanced visualization can improve decisions regarding transplant suitability of donor corneas.
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spelling doaj-art-6205583f721f40008997c45f15f9f9b32025-02-03T01:03:31ZengWileyJournal of Ophthalmology2090-004X2090-00582013-01-01201310.1155/2013/397680397680Use of Fourier-Domain Optical Coherence Tomography to Evaluate Anterior Stromal Opacities in Donor CorneasMatthew R. Bald0Christopher Stoeger1Joshua Galloway2Maolong Tang3Jeffrey Holiman4David Huang5Center for Ophthalmic Optics & Lasers, Casey Eye Institute and Department of Ophthalmology, Oregon Health & Science University, 3375 SW Terwilliger Boulevard, Portland, OR 97239-4197, USALions VisionGift, Portland, OR 971214-5303, USALions VisionGift, Portland, OR 971214-5303, USACenter for Ophthalmic Optics & Lasers, Casey Eye Institute and Department of Ophthalmology, Oregon Health & Science University, 3375 SW Terwilliger Boulevard, Portland, OR 97239-4197, USALions VisionGift, Portland, OR 971214-5303, USACenter for Ophthalmic Optics & Lasers, Casey Eye Institute and Department of Ophthalmology, Oregon Health & Science University, 3375 SW Terwilliger Boulevard, Portland, OR 97239-4197, USAPurpose. To evaluate Fourier-domain optical coherence tomography (FD-OCT) as an adjunct to traditional slit lamp examination of donor corneas with suspected Anterior Stromal Opacities. Methods. Seven corneas suspected of having anterior stromal opacities by slit lamp examination were evaluated with FD-OCT. Each cornea was evaluated to confirm the presence of opacity and, if present, the depth of opacity was measured. Results. The opacity depth ranged from 82 μm to 624 μm. The initial slit lamp impressions of five of the seven corneas were confirmed by OCT. In two corneas, the OCT findings were different from the initial slit lamp impressions. Slit lamp examination of the first cornea gave the impression of anterior stromal scarring, but OCT showed that the opacity was limited to the epithelium. Slit lamp examination of the second cornea suggested opacity limited to the epithelium, but OCT identified significant sub-Bowman's scarring. In all cases, the Eye Bank Technicians reported that the location and depth of corneal opacity were more sharply defined by OCT than by slit lamp. Conclusion. The high resolution of OCT makes it easier to determine the location of corneal opacities compared to slit lamp examinations. This enhanced visualization can improve decisions regarding transplant suitability of donor corneas.http://dx.doi.org/10.1155/2013/397680
spellingShingle Matthew R. Bald
Christopher Stoeger
Joshua Galloway
Maolong Tang
Jeffrey Holiman
David Huang
Use of Fourier-Domain Optical Coherence Tomography to Evaluate Anterior Stromal Opacities in Donor Corneas
Journal of Ophthalmology
title Use of Fourier-Domain Optical Coherence Tomography to Evaluate Anterior Stromal Opacities in Donor Corneas
title_full Use of Fourier-Domain Optical Coherence Tomography to Evaluate Anterior Stromal Opacities in Donor Corneas
title_fullStr Use of Fourier-Domain Optical Coherence Tomography to Evaluate Anterior Stromal Opacities in Donor Corneas
title_full_unstemmed Use of Fourier-Domain Optical Coherence Tomography to Evaluate Anterior Stromal Opacities in Donor Corneas
title_short Use of Fourier-Domain Optical Coherence Tomography to Evaluate Anterior Stromal Opacities in Donor Corneas
title_sort use of fourier domain optical coherence tomography to evaluate anterior stromal opacities in donor corneas
url http://dx.doi.org/10.1155/2013/397680
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