Therapeutic drug monitoring vs. pharmacogenetic testing in the context of elevated olanzapine concentrations and prior clozapine intolerability: a case study

Abstract Background Strong evidence for therapeutic drug monitoring exists for olanzapine and clozapine, however, olanzapine therapeutic drug monitoring is often underutilized. Evidence for pharmacogenomic-guided dosing of antipsychotics is not as robust, especially for cytochrome P450 1A2 metaboliz...

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Bibliographic Details
Main Authors: Farah Khorassani, Ricardo Azevedo, Reza Farokhpay
Format: Article
Language:English
Published: BMC 2024-12-01
Series:BMC Psychiatry
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Online Access:https://doi.org/10.1186/s12888-024-06319-5
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