Effects of Continuous Positive Airway Pressure on Sleep EEG Characteristics in Patients with Primary Central Sleep Apnea Syndrome
This study aimed to investigate the effects of continuous positive airway pressure (CPAP) on the electroencephalographic (EEG) characteristics of patients with primary central sleep apnea syndrome (CSAS). Nine patients with primary CSAS were enrolled in this study. The raw sleep EEG data were analyz...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2021-01-01
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| Series: | Canadian Respiratory Journal |
| Online Access: | http://dx.doi.org/10.1155/2021/6657724 |
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| _version_ | 1832566407554924544 |
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| author | Cheng Zhang Kun Chen Guangfa Wang Jue Zhang Jing Ma |
| author_facet | Cheng Zhang Kun Chen Guangfa Wang Jue Zhang Jing Ma |
| author_sort | Cheng Zhang |
| collection | DOAJ |
| description | This study aimed to investigate the effects of continuous positive airway pressure (CPAP) on the electroencephalographic (EEG) characteristics of patients with primary central sleep apnea syndrome (CSAS). Nine patients with primary CSAS were enrolled in this study. The raw sleep EEG data were analyzed based on two main factors: fractal dimension (FD) and zero-crossing rate of detrended FD. Additionally, conventional EEG spectral analysis in the delta, theta, alpha, and beta bands was conducted using a fast Fourier transform. The FD in patients with primary CSAS who underwent CPAP treatment was significantly decreased during nonrapid eye movement (NREM) sleep but increased during rapid eye movement (REM) sleep (p<0.05). Regarding the EEG spectral analysis, the alpha power increased, while the delta/alpha ratio decreased during REM sleep in patients with CSAS (p<0.05). In conclusion, CPAP treatment can reduce FD in NREM sleep and increase FD during REM sleep in patients with primary CSAS. FD may be used as a new biomarker of EEG stability and improvement in brain function after CPAP treatment for primary CSAS. |
| format | Article |
| id | doaj-art-61d378d6217e472ab32da8d623186503 |
| institution | Kabale University |
| issn | 1198-2241 1916-7245 |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Canadian Respiratory Journal |
| spelling | doaj-art-61d378d6217e472ab32da8d6231865032025-02-03T01:04:08ZengWileyCanadian Respiratory Journal1198-22411916-72452021-01-01202110.1155/2021/66577246657724Effects of Continuous Positive Airway Pressure on Sleep EEG Characteristics in Patients with Primary Central Sleep Apnea SyndromeCheng Zhang0Kun Chen1Guangfa Wang2Jue Zhang3Jing Ma4Department of Respiratory and Critical Care Medicine, Peking University First Hospital, Beijing 100034, ChinaAcademy of Advanced Interdisciplinary Studies, Peking University, Beijing 100871, ChinaDepartment of Respiratory and Critical Care Medicine, Peking University First Hospital, Beijing 100034, ChinaAcademy of Advanced Interdisciplinary Studies, Peking University, Beijing 100871, ChinaDepartment of Respiratory and Critical Care Medicine, Peking University First Hospital, Beijing 100034, ChinaThis study aimed to investigate the effects of continuous positive airway pressure (CPAP) on the electroencephalographic (EEG) characteristics of patients with primary central sleep apnea syndrome (CSAS). Nine patients with primary CSAS were enrolled in this study. The raw sleep EEG data were analyzed based on two main factors: fractal dimension (FD) and zero-crossing rate of detrended FD. Additionally, conventional EEG spectral analysis in the delta, theta, alpha, and beta bands was conducted using a fast Fourier transform. The FD in patients with primary CSAS who underwent CPAP treatment was significantly decreased during nonrapid eye movement (NREM) sleep but increased during rapid eye movement (REM) sleep (p<0.05). Regarding the EEG spectral analysis, the alpha power increased, while the delta/alpha ratio decreased during REM sleep in patients with CSAS (p<0.05). In conclusion, CPAP treatment can reduce FD in NREM sleep and increase FD during REM sleep in patients with primary CSAS. FD may be used as a new biomarker of EEG stability and improvement in brain function after CPAP treatment for primary CSAS.http://dx.doi.org/10.1155/2021/6657724 |
| spellingShingle | Cheng Zhang Kun Chen Guangfa Wang Jue Zhang Jing Ma Effects of Continuous Positive Airway Pressure on Sleep EEG Characteristics in Patients with Primary Central Sleep Apnea Syndrome Canadian Respiratory Journal |
| title | Effects of Continuous Positive Airway Pressure on Sleep EEG Characteristics in Patients with Primary Central Sleep Apnea Syndrome |
| title_full | Effects of Continuous Positive Airway Pressure on Sleep EEG Characteristics in Patients with Primary Central Sleep Apnea Syndrome |
| title_fullStr | Effects of Continuous Positive Airway Pressure on Sleep EEG Characteristics in Patients with Primary Central Sleep Apnea Syndrome |
| title_full_unstemmed | Effects of Continuous Positive Airway Pressure on Sleep EEG Characteristics in Patients with Primary Central Sleep Apnea Syndrome |
| title_short | Effects of Continuous Positive Airway Pressure on Sleep EEG Characteristics in Patients with Primary Central Sleep Apnea Syndrome |
| title_sort | effects of continuous positive airway pressure on sleep eeg characteristics in patients with primary central sleep apnea syndrome |
| url | http://dx.doi.org/10.1155/2021/6657724 |
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