Development of a low-cost flexible potentiometric detector and its integrated system for electrochemical sensing of electrolytes in human sweat

In the current era of wearable electrochemical sensors, there is a growing demand for a potentiometric detector that exhibits exceptional flexibility, comfortable wearability, and stability in electrolyte sensing. The present study designs and validates a low-cost (costs 17 dollars), small area (siz...

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Main Authors: Chaojiang Li, Yuxuan Liu, Guodong Liu, Qifeng Tan, Xiaolong Dou, Yuting Xie, Xianchao Zhang
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Sensors and Actuators Reports
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Online Access:http://www.sciencedirect.com/science/article/pii/S2666053925000062
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author Chaojiang Li
Yuxuan Liu
Guodong Liu
Qifeng Tan
Xiaolong Dou
Yuting Xie
Xianchao Zhang
author_facet Chaojiang Li
Yuxuan Liu
Guodong Liu
Qifeng Tan
Xiaolong Dou
Yuting Xie
Xianchao Zhang
author_sort Chaojiang Li
collection DOAJ
description In the current era of wearable electrochemical sensors, there is a growing demand for a potentiometric detector that exhibits exceptional flexibility, comfortable wearability, and stability in electrolyte sensing. The present study designs and validates a low-cost (costs 17 dollars), small area (size of 4 × 5.8 cm2), highly flexible potentiometric detector, which is facilitated through the utilization of cost-effective components, flexible printed circuit boards, and Bluetooth low energy modules. Electrolyte electrochemical detection has been achieved by integrating wearable microfluidic electrochemical sensing devices and establishing wireless communication with smartphone applications. The efficacy of this designed flexible potentiometric detector is demonstrated in sodium and calcium ions detection, indicating comparable results to those obtained from commercial electrochemical workstations. By comparing the detection results with those obtained from ion chromatography, the flexible potentiometric detector is proved to be useful for a real-time, on-body quantitative analysis of various ion concentrations in human sweat.
format Article
id doaj-art-61c5f8535bb4487cbd5b8c83215936eb
institution Kabale University
issn 2666-0539
language English
publishDate 2025-06-01
publisher Elsevier
record_format Article
series Sensors and Actuators Reports
spelling doaj-art-61c5f8535bb4487cbd5b8c83215936eb2025-01-22T05:44:05ZengElsevierSensors and Actuators Reports2666-05392025-06-019100286Development of a low-cost flexible potentiometric detector and its integrated system for electrochemical sensing of electrolytes in human sweatChaojiang Li0Yuxuan Liu1Guodong Liu2Qifeng Tan3Xiaolong Dou4Yuting Xie5Xianchao Zhang6School of Mechanical Engineering, Beijing Institute of Technology, 5 South Zhongguancun Street, Haidian District, Beijing 100081, PR China; Yangtze Delta Region Academy of Beijing Institute of Technology, Jiaxing, 314011, PR ChinaYangtze Delta Region Academy of Beijing Institute of Technology, Jiaxing, 314011, PR ChinaSchool of Mechanical Engineering, Beijing Institute of Technology, 5 South Zhongguancun Street, Haidian District, Beijing 100081, PR China; Yangtze Delta Region Academy of Beijing Institute of Technology, Jiaxing, 314011, PR China; Corresponding authors.School of Mechanical Engineering, Jiangsu University of Technology, 213001, Zhongwu Avenue, Changzhou, PR ChinaSchool of Mechanical Engineering, Beijing Institute of Technology, 5 South Zhongguancun Street, Haidian District, Beijing 100081, PR China; Yangtze Delta Region Academy of Beijing Institute of Technology, Jiaxing, 314011, PR ChinaSchool of Mechanical Engineering, Beijing Institute of Technology, 5 South Zhongguancun Street, Haidian District, Beijing 100081, PR ChinaKey Laboratory of Medical Electronics and Digital Health of Zhejiang Province, Jiaxing University, Jiaxing, 314011, PR China; Provincial Key Laboratory of Multimodal Perceiving and Intelligent Systems, Jiaxing University, Jiaxing, 314001, PR China; Corresponding authors.In the current era of wearable electrochemical sensors, there is a growing demand for a potentiometric detector that exhibits exceptional flexibility, comfortable wearability, and stability in electrolyte sensing. The present study designs and validates a low-cost (costs 17 dollars), small area (size of 4 × 5.8 cm2), highly flexible potentiometric detector, which is facilitated through the utilization of cost-effective components, flexible printed circuit boards, and Bluetooth low energy modules. Electrolyte electrochemical detection has been achieved by integrating wearable microfluidic electrochemical sensing devices and establishing wireless communication with smartphone applications. The efficacy of this designed flexible potentiometric detector is demonstrated in sodium and calcium ions detection, indicating comparable results to those obtained from commercial electrochemical workstations. By comparing the detection results with those obtained from ion chromatography, the flexible potentiometric detector is proved to be useful for a real-time, on-body quantitative analysis of various ion concentrations in human sweat.http://www.sciencedirect.com/science/article/pii/S2666053925000062Electrochemical sensorFlexible potentiometric detectorSweetPrinted circuit boardsSmart terminal
spellingShingle Chaojiang Li
Yuxuan Liu
Guodong Liu
Qifeng Tan
Xiaolong Dou
Yuting Xie
Xianchao Zhang
Development of a low-cost flexible potentiometric detector and its integrated system for electrochemical sensing of electrolytes in human sweat
Sensors and Actuators Reports
Electrochemical sensor
Flexible potentiometric detector
Sweet
Printed circuit boards
Smart terminal
title Development of a low-cost flexible potentiometric detector and its integrated system for electrochemical sensing of electrolytes in human sweat
title_full Development of a low-cost flexible potentiometric detector and its integrated system for electrochemical sensing of electrolytes in human sweat
title_fullStr Development of a low-cost flexible potentiometric detector and its integrated system for electrochemical sensing of electrolytes in human sweat
title_full_unstemmed Development of a low-cost flexible potentiometric detector and its integrated system for electrochemical sensing of electrolytes in human sweat
title_short Development of a low-cost flexible potentiometric detector and its integrated system for electrochemical sensing of electrolytes in human sweat
title_sort development of a low cost flexible potentiometric detector and its integrated system for electrochemical sensing of electrolytes in human sweat
topic Electrochemical sensor
Flexible potentiometric detector
Sweet
Printed circuit boards
Smart terminal
url http://www.sciencedirect.com/science/article/pii/S2666053925000062
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