Relationships between intensity, duration, cumulative dose, and timing of smoking with age at menopause: A pooled analysis of individual data from 17 observational studies.

Relationships between intensity, duration, cumulative dose, and timing of smoking with age at menopause: A pooled analysis of individual data from 17 observational studies.

<h4>Background</h4>Cigarette smoking is associated with earlier menopause, but the impact of being a former smoker and any dose-response relationships on the degree of smoking and age at menopause have been less clear. If the toxic impact of cigarette smoking on ovarian function is irrev...

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Main Authors: Dongshan Zhu, Hsin-Fang Chung, Nirmala Pandeya, Annette J Dobson, Janet E Cade, Darren C Greenwood, Sybil L Crawford, Nancy E Avis, Ellen B Gold, Ellen S Mitchell, Nancy F Woods, Debra Anderson, Daniel E Brown, Lynnette L Sievert, Eric J Brunner, Diana Kuh, Rebecca Hardy, Kunihiko Hayashi, Jung Su Lee, Hideki Mizunuma, Graham G Giles, Fiona Bruinsma, Therese Tillin, Mette Kildevæld Simonsen, Hans-Olov Adami, Elisabete Weiderpass, Marianne Canonico, Marie-Laure Ancelin, Panayotes Demakakos, Gita D Mishra
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-11-01
Series:PLoS Medicine
Online Access:https://doi.org/10.1371/journal.pmed.1002704
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