What Is a Genome?
The genome is often described as the information repository of an organism. Whether millions or billions of letters of DNA, its transmission across generations confers the principal medium for inheritance of organismal traits. Several emerging areas of research demonstrate that this definition is an...
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2016-07-01
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| Series: | PLoS Genetics |
| Online Access: | https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1006181&type=printable |
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| _version_ | 1849722306550562816 |
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| author | Aaron David Goldman Laura F Landweber |
| author_facet | Aaron David Goldman Laura F Landweber |
| author_sort | Aaron David Goldman |
| collection | DOAJ |
| description | The genome is often described as the information repository of an organism. Whether millions or billions of letters of DNA, its transmission across generations confers the principal medium for inheritance of organismal traits. Several emerging areas of research demonstrate that this definition is an oversimplification. Here, we explore ways in which a deeper understanding of genomic diversity and cell physiology is challenging the concepts of physical permanence attached to the genome as well as its role as the sole information source for an organism. |
| format | Article |
| id | doaj-art-61b25d97d4d84d7c91ef6d79f8d8b2df |
| institution | DOAJ |
| issn | 1553-7390 1553-7404 |
| language | English |
| publishDate | 2016-07-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS Genetics |
| spelling | doaj-art-61b25d97d4d84d7c91ef6d79f8d8b2df2025-08-20T03:11:22ZengPublic Library of Science (PLoS)PLoS Genetics1553-73901553-74042016-07-01127e100618110.1371/journal.pgen.1006181What Is a Genome?Aaron David GoldmanLaura F LandweberThe genome is often described as the information repository of an organism. Whether millions or billions of letters of DNA, its transmission across generations confers the principal medium for inheritance of organismal traits. Several emerging areas of research demonstrate that this definition is an oversimplification. Here, we explore ways in which a deeper understanding of genomic diversity and cell physiology is challenging the concepts of physical permanence attached to the genome as well as its role as the sole information source for an organism.https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1006181&type=printable |
| spellingShingle | Aaron David Goldman Laura F Landweber What Is a Genome? PLoS Genetics |
| title | What Is a Genome? |
| title_full | What Is a Genome? |
| title_fullStr | What Is a Genome? |
| title_full_unstemmed | What Is a Genome? |
| title_short | What Is a Genome? |
| title_sort | what is a genome |
| url | https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1006181&type=printable |
| work_keys_str_mv | AT aarondavidgoldman whatisagenome AT lauraflandweber whatisagenome |