The Efficacy and Safety of Folate Receptor α‐Targeted Antibody‐Drug Conjugate Therapy in Patients With High‐Grade Epithelial Ovarian, Primary Peritoneal, or Fallopian Tube Cancers: A Systematic Review and Meta‐Analysis

The Efficacy and Safety of Folate Receptor α‐Targeted Antibody‐Drug Conjugate Therapy in Patients With High‐Grade Epithelial Ovarian, Primary Peritoneal, or Fallopian Tube Cancers: A Systematic Review and Meta‐Analysis

ABSTRACT Background Antibody‐drug conjugates (ADC) have emerged as a highly promising systemic option in the treatment of recurrent ovarian cancer. The present study aimed to evaluate the treatment efficacy of folate receptor α (FRα)‐targeting ADCs, associated treatment‐related adverse events (TRAEs...

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Main Authors: Eun Taeg Kim, Ji Hyun Kim, Eun Young Park, In Hye Song, Han Song Park, Sang‐Yoon Park, Myong Cheol Lim
Format: Article
Language:English
Published: Wiley 2024-11-01
Series:Cancer Medicine
Subjects:
adverse event
antibody‐drug conjugate
folate receptor alpha
mirvetuximab soravtansine
ovarian cancer
Online Access:https://doi.org/10.1002/cam4.70392
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https://doi.org/10.1002/cam4.70392

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