Novel In Vitro Assays for the Characterization of EMT in Tumourigenesis
Background: Two novel assays quantifying Epithelial to Mesenchymal Transition (EMT) were compared to traditional motility and migration assays. TGF-β1 treatment of AY-27 rat bladder cancer cells acted as a model of EMT in tumourigenesis.
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| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2010-01-01
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| Series: | Cellular Oncology |
| Online Access: | http://dx.doi.org/10.3233/CLO-2009-0501 |
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| _version_ | 1832567795029639168 |
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| author | Vincent Koo Amgad El Mekabaty Peter Hamilton Perry Maxwell Osama Sharaf Jim Diamond Jenny Watson Kathleen Williamson |
| author_facet | Vincent Koo Amgad El Mekabaty Peter Hamilton Perry Maxwell Osama Sharaf Jim Diamond Jenny Watson Kathleen Williamson |
| author_sort | Vincent Koo |
| collection | DOAJ |
| description | Background: Two novel assays quantifying Epithelial to Mesenchymal Transition (EMT) were compared to traditional motility and migration assays. TGF-β1 treatment of AY-27 rat bladder cancer cells acted as a model of EMT in tumourigenesis. |
| format | Article |
| id | doaj-art-61474e5282f1458b9aacef398fff3af6 |
| institution | Kabale University |
| issn | 1570-5870 1875-8606 |
| language | English |
| publishDate | 2010-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Cellular Oncology |
| spelling | doaj-art-61474e5282f1458b9aacef398fff3af62025-02-03T01:00:27ZengWileyCellular Oncology1570-58701875-86062010-01-01321-2677610.3233/CLO-2009-0501Novel In Vitro Assays for the Characterization of EMT in TumourigenesisVincent Koo0Amgad El Mekabaty1Peter Hamilton2Perry Maxwell3Osama Sharaf4Jim Diamond5Jenny Watson6Kathleen Williamson7Uro-oncology Research Group, Centre for Cancer Research & Cell Biology, Queen’s University Belfast, Belfast, Northern Ireland, UKUro-oncology Research Group, Centre for Cancer Research & Cell Biology, Queen’s University Belfast, Belfast, Northern Ireland, UKBio-imaging & Informatics Research Group, Centre for Cancer Research & Cell Biology, Queen's University Belfast, Belfast, Northern Ireland, UKBelfast Health and Social Care Trust, Belfast, Northern Ireland, UKUro-oncology Research Group, Centre for Cancer Research & Cell Biology, Queen’s University Belfast, Belfast, Northern Ireland, UKBio-imaging & Informatics Research Group, Centre for Cancer Research & Cell Biology, Queen's University Belfast, Belfast, Northern Ireland, UKThe UCD Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Belfield, Dublin, IrelandUro-oncology Research Group, Centre for Cancer Research & Cell Biology, Queen’s University Belfast, Belfast, Northern Ireland, UKBackground: Two novel assays quantifying Epithelial to Mesenchymal Transition (EMT) were compared to traditional motility and migration assays. TGF-β1 treatment of AY-27 rat bladder cancer cells acted as a model of EMT in tumourigenesis.http://dx.doi.org/10.3233/CLO-2009-0501 |
| spellingShingle | Vincent Koo Amgad El Mekabaty Peter Hamilton Perry Maxwell Osama Sharaf Jim Diamond Jenny Watson Kathleen Williamson Novel In Vitro Assays for the Characterization of EMT in Tumourigenesis Cellular Oncology |
| title | Novel In Vitro Assays for the Characterization of EMT in Tumourigenesis |
| title_full | Novel In Vitro Assays for the Characterization of EMT in Tumourigenesis |
| title_fullStr | Novel In Vitro Assays for the Characterization of EMT in Tumourigenesis |
| title_full_unstemmed | Novel In Vitro Assays for the Characterization of EMT in Tumourigenesis |
| title_short | Novel In Vitro Assays for the Characterization of EMT in Tumourigenesis |
| title_sort | novel in vitro assays for the characterization of emt in tumourigenesis |
| url | http://dx.doi.org/10.3233/CLO-2009-0501 |
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