Acute Hepatitis Induced by Intravesical BCG Therapy: A Rare but Serious Complication
Bacillus Calmette and Guérin (BCG), widely used as a vaccination to prevent tuberculosis, is also used as immunotherapy, by intrabladder instillation, to treat superficial bladder cancers and prevent recurrence. Complications following instillation of BCG are most often localized reactions, such as...
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| Format: | Article |
| Language: | English |
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Wiley
2021-01-01
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| Series: | Case Reports in Hepatology |
| Online Access: | http://dx.doi.org/10.1155/2021/4574879 |
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| author | Hakima Abid Mouna Figuigui Sidi Adil Ibrahimi Mohamed El Abkari Mohamed Mzyiene Soufiane Ennaciri Ouima Justin Ziba Mohamed Jamal El Fassi Layla Tahiri Elousrouti Laila Chbani |
| author_facet | Hakima Abid Mouna Figuigui Sidi Adil Ibrahimi Mohamed El Abkari Mohamed Mzyiene Soufiane Ennaciri Ouima Justin Ziba Mohamed Jamal El Fassi Layla Tahiri Elousrouti Laila Chbani |
| author_sort | Hakima Abid |
| collection | DOAJ |
| description | Bacillus Calmette and Guérin (BCG), widely used as a vaccination to prevent tuberculosis, is also used as immunotherapy, by intrabladder instillation, to treat superficial bladder cancers and prevent recurrence. Complications following instillation of BCG are most often localized reactions, such as cystitis or hematuria. They can more rarely be generalized and potentially severe such as hepatitis, pneumopathies, aortitis, and localization to hematopoietic tissue. We have reported the observation of a 47-year-old patient followed up for a bladder tumor operated for transurethral resection of the bladder, then having benefited from an instillation of BCG therapy complicated by occurrence a week later of an acute hepatitis. The diagnostic time was 2 days, and the outcome was favorable with corticosteroid therapy. |
| format | Article |
| id | doaj-art-6142073b78c74d2d8da06e054e4b18e6 |
| institution | Kabale University |
| issn | 2090-6587 2090-6595 |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Hepatology |
| spelling | doaj-art-6142073b78c74d2d8da06e054e4b18e62025-02-03T07:24:02ZengWileyCase Reports in Hepatology2090-65872090-65952021-01-01202110.1155/2021/45748794574879Acute Hepatitis Induced by Intravesical BCG Therapy: A Rare but Serious ComplicationHakima Abid0Mouna Figuigui1Sidi Adil Ibrahimi2Mohamed El Abkari3Mohamed Mzyiene4Soufiane Ennaciri5Ouima Justin Ziba6Mohamed Jamal El Fassi7Layla Tahiri Elousrouti8Laila Chbani9Department of Hepato-Gastroenterology, University Hospital Hassan II-Fez, Laboratory of Human Pathology, Biomedicine and Environment, Fes, MoroccoDepartment of Hepato-Gastroenterology, University Hospital Hassan II-Fez, Laboratory of Human Pathology, Biomedicine and Environment, Fes, MoroccoDepartment of Hepato-Gastroenterology, University Hospital Hassan II-Fez, Laboratory of Human Pathology, Biomedicine and Environment, Fes, MoroccoDepartment of Hepato-Gastroenterology, University Hospital Hassan II-Fez, Laboratory of Human Pathology, Biomedicine and Environment, Fes, MoroccoFaculty of Medicine and Pharmacy of Fez, Sidi Mohamed Ben Abdellah University Fez-Morocco, Fes, MoroccoFaculty of Medicine and Pharmacy of Fez, Sidi Mohamed Ben Abdellah University Fez-Morocco, Fes, MoroccoFaculty of Medicine and Pharmacy of Fez, Sidi Mohamed Ben Abdellah University Fez-Morocco, Fes, MoroccoFaculty of Medicine and Pharmacy of Fez, Sidi Mohamed Ben Abdellah University Fez-Morocco, Fes, MoroccoFaculty of Medicine and Pharmacy of Fez, Sidi Mohamed Ben Abdellah University Fez-Morocco, Fes, MoroccoFaculty of Medicine and Pharmacy of Fez, Sidi Mohamed Ben Abdellah University Fez-Morocco, Fes, MoroccoBacillus Calmette and Guérin (BCG), widely used as a vaccination to prevent tuberculosis, is also used as immunotherapy, by intrabladder instillation, to treat superficial bladder cancers and prevent recurrence. Complications following instillation of BCG are most often localized reactions, such as cystitis or hematuria. They can more rarely be generalized and potentially severe such as hepatitis, pneumopathies, aortitis, and localization to hematopoietic tissue. We have reported the observation of a 47-year-old patient followed up for a bladder tumor operated for transurethral resection of the bladder, then having benefited from an instillation of BCG therapy complicated by occurrence a week later of an acute hepatitis. The diagnostic time was 2 days, and the outcome was favorable with corticosteroid therapy.http://dx.doi.org/10.1155/2021/4574879 |
| spellingShingle | Hakima Abid Mouna Figuigui Sidi Adil Ibrahimi Mohamed El Abkari Mohamed Mzyiene Soufiane Ennaciri Ouima Justin Ziba Mohamed Jamal El Fassi Layla Tahiri Elousrouti Laila Chbani Acute Hepatitis Induced by Intravesical BCG Therapy: A Rare but Serious Complication Case Reports in Hepatology |
| title | Acute Hepatitis Induced by Intravesical BCG Therapy: A Rare but Serious Complication |
| title_full | Acute Hepatitis Induced by Intravesical BCG Therapy: A Rare but Serious Complication |
| title_fullStr | Acute Hepatitis Induced by Intravesical BCG Therapy: A Rare but Serious Complication |
| title_full_unstemmed | Acute Hepatitis Induced by Intravesical BCG Therapy: A Rare but Serious Complication |
| title_short | Acute Hepatitis Induced by Intravesical BCG Therapy: A Rare but Serious Complication |
| title_sort | acute hepatitis induced by intravesical bcg therapy a rare but serious complication |
| url | http://dx.doi.org/10.1155/2021/4574879 |
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