Genomic virulence markers are associated with severe outcomes in patients with Pseudomonas aeruginosa bloodstream infection

Genomic virulence markers are associated with severe outcomes in patients with Pseudomonas aeruginosa bloodstream infection

Abstract Background Pseudomonas aeruginosa (PA) bloodstream infection (BSI) is a common healthcare-associated complication linked to antimicrobial resistance and high mortality. Ongoing clinical trials are exploring novel anti-virulence agents, yet studies on how bacterial virulence affects PA infec...

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Main Authors: John Karlsson Valik, Christian G. Giske, Badrul Hasan, Mónica Gozalo-Margüello, Luis Martínez-Martínez, Manica Mueller Premru, Žiga Martinčič, Bojana Beović, Sofia Maraki, Maria Zacharioudaki, Diamantis Kofteridis, Kate McCarthy, David Paterson, Marina de Cueto, Isabel Morales, Leonard Leibovici, Tanya Babich, Fredrik Granath, Jesús Rodríguez-Baño, Antonio Oliver, Dafna Yahav, Pontus Nauclér
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:Communications Medicine
Online Access:https://doi.org/10.1038/s43856-024-00696-4
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