Coordinated Actions of FXR and LXR in Metabolism: From Pathogenesis to Pharmacological Targets for Type 2 Diabetes
Type 2 diabetes (T2D) is the most prevalent metabolic disease, and many people are suffering from its complications driven by hyperglycaemia and dyslipidaemia. Nuclear receptors (NRs) are ligand-inducible transcription factors that mediate changes to metabolic pathways within the body. As metabolic...
Saved in:
Main Authors: | Lin Ding, Shuguang Pang, Yongmei Sun, Yuling Tian, Li Yu, Ningning Dang |
---|---|
Format: | Article |
Language: | English |
Published: |
Wiley
2014-01-01
|
Series: | International Journal of Endocrinology |
Online Access: | http://dx.doi.org/10.1155/2014/751859 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
A mutation in LXRα uncovers a role for cholesterol sensing in limiting metabolic dysfunction-associated steatohepatitis
by: Alexis T. Clark, et al.
Published: (2025-01-01) -
FXR Mediates Adenylyl Cyclase 8 Expression in Pancreatic β-Cells
by: Xiangchen Kong, et al.
Published: (2019-01-01) -
Pathogenesis of Functional Biliary Pain and Pharmacology of Trimebutin
by: E. L. Bueverova, et al.
Published: (2024-03-01) -
CXC Chemokines in the Pathogenesis of Pulmonary Disease and Pharmacological Relevance
by: Kayode Komolafe, et al.
Published: (2022-01-01) -
Hsp90α promotes lipogenesis by stabilizing FASN and promoting FASN transcription via LXRα in hepatocellular carcinoma
by: Zihao Deng, et al.
Published: (2025-01-01)