Tryptophan-Kynurenine Pathway in COVID-19-Dependent Musculoskeletal Pathology: A Minireview
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes coronavirus disease 2019 (COVID-19), affecting multiple organ systems, including the respiratory tract and lungs. Several studies have reported that the tryptophan-kynurenine pathway is altered in COVID-19 patients. The tryptophan-k...
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| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2021-01-01
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| Series: | Mediators of Inflammation |
| Online Access: | http://dx.doi.org/10.1155/2021/2911578 |
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| _version_ | 1832567729209475072 |
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| author | Sagar Vyavahare Sandeep Kumar Nicholas Cantu Ravindra Kolhe Wendy B. Bollag Meghan E. McGee-Lawrence William D. Hill Mark W. Hamrick Carlos M. Isales Sadanand Fulzele |
| author_facet | Sagar Vyavahare Sandeep Kumar Nicholas Cantu Ravindra Kolhe Wendy B. Bollag Meghan E. McGee-Lawrence William D. Hill Mark W. Hamrick Carlos M. Isales Sadanand Fulzele |
| author_sort | Sagar Vyavahare |
| collection | DOAJ |
| description | Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes coronavirus disease 2019 (COVID-19), affecting multiple organ systems, including the respiratory tract and lungs. Several studies have reported that the tryptophan-kynurenine pathway is altered in COVID-19 patients. The tryptophan-kynurenine pathway plays a vital role in regulating inflammation, metabolism, immune responses, and musculoskeletal system biology. In this minireview, we surmise the effects of the kynurenine pathway in COVID-19 patients and how this pathway might impact muscle and bone biology. |
| format | Article |
| id | doaj-art-60eed5c1cc5d49b18eb3e7a27835801d |
| institution | Kabale University |
| issn | 0962-9351 1466-1861 |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Mediators of Inflammation |
| spelling | doaj-art-60eed5c1cc5d49b18eb3e7a27835801d2025-02-03T01:00:47ZengWileyMediators of Inflammation0962-93511466-18612021-01-01202110.1155/2021/29115782911578Tryptophan-Kynurenine Pathway in COVID-19-Dependent Musculoskeletal Pathology: A MinireviewSagar Vyavahare0Sandeep Kumar1Nicholas Cantu2Ravindra Kolhe3Wendy B. Bollag4Meghan E. McGee-Lawrence5William D. Hill6Mark W. Hamrick7Carlos M. Isales8Sadanand Fulzele9Department of Cell Biology and Anatomy, Augusta University, Augusta, GA, USADepartment of Cell Biology and Anatomy, Augusta University, Augusta, GA, USADepartment of Medicine, Augusta University, Augusta, GA, USADepartment of Pathology, Augusta University, Augusta, GA, USADepartment of Physiology, Augusta University, Augusta, GA, USADepartment of Cell Biology and Anatomy, Augusta University, Augusta, GA, USADepartment of Pathology, Medical University of South Carolina, Charleston, SC, USADepartment of Cell Biology and Anatomy, Augusta University, Augusta, GA, USADepartment of Medicine, Augusta University, Augusta, GA, USADepartment of Cell Biology and Anatomy, Augusta University, Augusta, GA, USASevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes coronavirus disease 2019 (COVID-19), affecting multiple organ systems, including the respiratory tract and lungs. Several studies have reported that the tryptophan-kynurenine pathway is altered in COVID-19 patients. The tryptophan-kynurenine pathway plays a vital role in regulating inflammation, metabolism, immune responses, and musculoskeletal system biology. In this minireview, we surmise the effects of the kynurenine pathway in COVID-19 patients and how this pathway might impact muscle and bone biology.http://dx.doi.org/10.1155/2021/2911578 |
| spellingShingle | Sagar Vyavahare Sandeep Kumar Nicholas Cantu Ravindra Kolhe Wendy B. Bollag Meghan E. McGee-Lawrence William D. Hill Mark W. Hamrick Carlos M. Isales Sadanand Fulzele Tryptophan-Kynurenine Pathway in COVID-19-Dependent Musculoskeletal Pathology: A Minireview Mediators of Inflammation |
| title | Tryptophan-Kynurenine Pathway in COVID-19-Dependent Musculoskeletal Pathology: A Minireview |
| title_full | Tryptophan-Kynurenine Pathway in COVID-19-Dependent Musculoskeletal Pathology: A Minireview |
| title_fullStr | Tryptophan-Kynurenine Pathway in COVID-19-Dependent Musculoskeletal Pathology: A Minireview |
| title_full_unstemmed | Tryptophan-Kynurenine Pathway in COVID-19-Dependent Musculoskeletal Pathology: A Minireview |
| title_short | Tryptophan-Kynurenine Pathway in COVID-19-Dependent Musculoskeletal Pathology: A Minireview |
| title_sort | tryptophan kynurenine pathway in covid 19 dependent musculoskeletal pathology a minireview |
| url | http://dx.doi.org/10.1155/2021/2911578 |
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