FORMULATION OF CREAM BODY SCRUB FROM ETHANOL EXTRACT OF CASSAVA LEAVES (Manihot esculenta) AS ANTIOXIDANT
Background : Plant cassava leaves (Manihot esculenta) are known flavonoid is efficacious as antioxidant. Antioxidant can prevent damage to the skin by reducing free radical activity. Purpose : The purpose of this study to determine the concentration of ethanol extract of leaves of cassava can be for...
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| Format: | Article |
| Language: | English |
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Universitas Airlangga
2020-07-01
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| Series: | Journal of Vocational Health Studies |
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| Online Access: | https://e-journal.unair.ac.id/JVHS/article/view/21180 |
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| author | Fadhliyah Malik Suryani Suryani Sunandar Ihsan Elvianti Meilany Rini Hamsidi |
| author_facet | Fadhliyah Malik Suryani Suryani Sunandar Ihsan Elvianti Meilany Rini Hamsidi |
| author_sort | Fadhliyah Malik |
| collection | DOAJ |
| description | Background : Plant cassava leaves (Manihot esculenta) are known flavonoid is efficacious as antioxidant. Antioxidant can prevent damage to the skin by reducing free radical activity. Purpose : The purpose of this study to determine the concentration of ethanol extract of leaves of cassava can be formulated into dosage cream body scrub which have antioxidant activity. Method : Cassava leaf extract obtained by maceration using 97% ethanol. Determination of antioxidant activity by the method of reduction of free radical DPPH (1,1-diphenyl-2-picryl-hydrazyl). Result : The ethanol extract of cassava leaves are formulated into dosage cream body scrub with concentration variations 0,0085 mg/mL (formula 1), 0,017 mg/mL (formula 2), and 0,0255 mg/mL (formula 3). Stability test preparation cream body scrub using cycling tests performed for 6 cycles. Preparation cream body scrub to formula I has a moderate antioxidant activity with IC50 158,16 µg/mL, formula 2 has an active antioxidant activity with IC50 66,59 µg/mL, and formula 3 has a stronger antioxidant activity with IC50 38,80 µg/mL. Conclusion : cream body scrub and cassava ethanol extract does not irritate so it is safe to use. Preparations cream body scrub well have the most activity at a concentration of 0,0255 mg/mL with IC50 38,80 µg/mL. |
| format | Article |
| id | doaj-art-60ecaa67baaa4567ba82693eaae7bc8d |
| institution | Kabale University |
| issn | 2580-7161 2580-717X |
| language | English |
| publishDate | 2020-07-01 |
| publisher | Universitas Airlangga |
| record_format | Article |
| series | Journal of Vocational Health Studies |
| spelling | doaj-art-60ecaa67baaa4567ba82693eaae7bc8d2025-02-02T01:21:32ZengUniversitas AirlanggaJournal of Vocational Health Studies2580-71612580-717X2020-07-0141212810.20473/jvhs.V4.I1.2020.21-2810331FORMULATION OF CREAM BODY SCRUB FROM ETHANOL EXTRACT OF CASSAVA LEAVES (Manihot esculenta) AS ANTIOXIDANTFadhliyah Malik0Suryani Suryani1Sunandar Ihsan2Elvianti Meilany3Rini Hamsidi4Universitas Halu OleoUniversitas Halu OleoUniversitas Halu OleoUniversitas Halu OleoUniversitas AirlanggaBackground : Plant cassava leaves (Manihot esculenta) are known flavonoid is efficacious as antioxidant. Antioxidant can prevent damage to the skin by reducing free radical activity. Purpose : The purpose of this study to determine the concentration of ethanol extract of leaves of cassava can be formulated into dosage cream body scrub which have antioxidant activity. Method : Cassava leaf extract obtained by maceration using 97% ethanol. Determination of antioxidant activity by the method of reduction of free radical DPPH (1,1-diphenyl-2-picryl-hydrazyl). Result : The ethanol extract of cassava leaves are formulated into dosage cream body scrub with concentration variations 0,0085 mg/mL (formula 1), 0,017 mg/mL (formula 2), and 0,0255 mg/mL (formula 3). Stability test preparation cream body scrub using cycling tests performed for 6 cycles. Preparation cream body scrub to formula I has a moderate antioxidant activity with IC50 158,16 µg/mL, formula 2 has an active antioxidant activity with IC50 66,59 µg/mL, and formula 3 has a stronger antioxidant activity with IC50 38,80 µg/mL. Conclusion : cream body scrub and cassava ethanol extract does not irritate so it is safe to use. Preparations cream body scrub well have the most activity at a concentration of 0,0255 mg/mL with IC50 38,80 µg/mL.https://e-journal.unair.ac.id/JVHS/article/view/21180cassava leavesantioxidantdpph (1,1-diphenyl-2-picryl-hydrazyl)cream body scrub |
| spellingShingle | Fadhliyah Malik Suryani Suryani Sunandar Ihsan Elvianti Meilany Rini Hamsidi FORMULATION OF CREAM BODY SCRUB FROM ETHANOL EXTRACT OF CASSAVA LEAVES (Manihot esculenta) AS ANTIOXIDANT Journal of Vocational Health Studies cassava leaves antioxidant dpph (1,1-diphenyl-2-picryl-hydrazyl) cream body scrub |
| title | FORMULATION OF CREAM BODY SCRUB FROM ETHANOL EXTRACT OF CASSAVA LEAVES (Manihot esculenta) AS ANTIOXIDANT |
| title_full | FORMULATION OF CREAM BODY SCRUB FROM ETHANOL EXTRACT OF CASSAVA LEAVES (Manihot esculenta) AS ANTIOXIDANT |
| title_fullStr | FORMULATION OF CREAM BODY SCRUB FROM ETHANOL EXTRACT OF CASSAVA LEAVES (Manihot esculenta) AS ANTIOXIDANT |
| title_full_unstemmed | FORMULATION OF CREAM BODY SCRUB FROM ETHANOL EXTRACT OF CASSAVA LEAVES (Manihot esculenta) AS ANTIOXIDANT |
| title_short | FORMULATION OF CREAM BODY SCRUB FROM ETHANOL EXTRACT OF CASSAVA LEAVES (Manihot esculenta) AS ANTIOXIDANT |
| title_sort | formulation of cream body scrub from ethanol extract of cassava leaves manihot esculenta as antioxidant |
| topic | cassava leaves antioxidant dpph (1,1-diphenyl-2-picryl-hydrazyl) cream body scrub |
| url | https://e-journal.unair.ac.id/JVHS/article/view/21180 |
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