Refractory Asthma Treatment Is Complicated by Tracheobronchomalacia: Case Reports and Review of the Literature

Tracheobronchomalacia (TBM) is defined as the condition where the airway lumen narrows more than 50 percent. The acquired TBM usually occurs in adults; however, the prevalence of TBM in asthma is unknown. We report two cases of severe asthma in elderly patients that could not be controlled with high...

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Main Authors: Sawad Boonpiyathad, Atik Sangasapaviliya
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Case Reports in Medicine
Online Access:http://dx.doi.org/10.1155/2013/735058
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author Sawad Boonpiyathad
Atik Sangasapaviliya
author_facet Sawad Boonpiyathad
Atik Sangasapaviliya
author_sort Sawad Boonpiyathad
collection DOAJ
description Tracheobronchomalacia (TBM) is defined as the condition where the airway lumen narrows more than 50 percent. The acquired TBM usually occurs in adults; however, the prevalence of TBM in asthma is unknown. We report two cases of severe asthma in elderly patients that could not be controlled with higher medication use. Case 1 was a 70-year-old woman with sever persistent asthma for 10 years, presented with uncontrolled symptoms for 4 months. A CT of the chest showed collapse of the trachea at the posterior wall. Case 2 involved a 72-year-old woman with partly controlled asthma presenting with uncontrolled symptoms for 3 months. A CT of the chest showed normal distal tracheal anteroposterior diameter. However, bronchoscopy showed bronchomalacia at the right and left bronchus of the lower lungs. Patients who have severe asthma, despite adequate treatment with medication, should be further investigated to exclude other diseases that have clinical features similar to asthma such as tracheobronchomalacia, particularly in the elderly.
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institution Kabale University
issn 1687-9627
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publishDate 2013-01-01
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series Case Reports in Medicine
spelling doaj-art-60e22f6086c044f0ab3a17aada4f749c2025-02-03T01:30:27ZengWileyCase Reports in Medicine1687-96271687-96352013-01-01201310.1155/2013/735058735058Refractory Asthma Treatment Is Complicated by Tracheobronchomalacia: Case Reports and Review of the LiteratureSawad Boonpiyathad0Atik Sangasapaviliya1Division of Allergy and Clinical Immunology, Department of Medicine, Phramongkutklao Hospital, Bangkok 10400, ThailandDivision of Allergy and Clinical Immunology, Department of Medicine, Phramongkutklao Hospital, Bangkok 10400, ThailandTracheobronchomalacia (TBM) is defined as the condition where the airway lumen narrows more than 50 percent. The acquired TBM usually occurs in adults; however, the prevalence of TBM in asthma is unknown. We report two cases of severe asthma in elderly patients that could not be controlled with higher medication use. Case 1 was a 70-year-old woman with sever persistent asthma for 10 years, presented with uncontrolled symptoms for 4 months. A CT of the chest showed collapse of the trachea at the posterior wall. Case 2 involved a 72-year-old woman with partly controlled asthma presenting with uncontrolled symptoms for 3 months. A CT of the chest showed normal distal tracheal anteroposterior diameter. However, bronchoscopy showed bronchomalacia at the right and left bronchus of the lower lungs. Patients who have severe asthma, despite adequate treatment with medication, should be further investigated to exclude other diseases that have clinical features similar to asthma such as tracheobronchomalacia, particularly in the elderly.http://dx.doi.org/10.1155/2013/735058
spellingShingle Sawad Boonpiyathad
Atik Sangasapaviliya
Refractory Asthma Treatment Is Complicated by Tracheobronchomalacia: Case Reports and Review of the Literature
Case Reports in Medicine
title Refractory Asthma Treatment Is Complicated by Tracheobronchomalacia: Case Reports and Review of the Literature
title_full Refractory Asthma Treatment Is Complicated by Tracheobronchomalacia: Case Reports and Review of the Literature
title_fullStr Refractory Asthma Treatment Is Complicated by Tracheobronchomalacia: Case Reports and Review of the Literature
title_full_unstemmed Refractory Asthma Treatment Is Complicated by Tracheobronchomalacia: Case Reports and Review of the Literature
title_short Refractory Asthma Treatment Is Complicated by Tracheobronchomalacia: Case Reports and Review of the Literature
title_sort refractory asthma treatment is complicated by tracheobronchomalacia case reports and review of the literature
url http://dx.doi.org/10.1155/2013/735058
work_keys_str_mv AT sawadboonpiyathad refractoryasthmatreatmentiscomplicatedbytracheobronchomalaciacasereportsandreviewoftheliterature
AT atiksangasapaviliya refractoryasthmatreatmentiscomplicatedbytracheobronchomalaciacasereportsandreviewoftheliterature