Refractory Asthma Treatment Is Complicated by Tracheobronchomalacia: Case Reports and Review of the Literature
Tracheobronchomalacia (TBM) is defined as the condition where the airway lumen narrows more than 50 percent. The acquired TBM usually occurs in adults; however, the prevalence of TBM in asthma is unknown. We report two cases of severe asthma in elderly patients that could not be controlled with high...
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2013-01-01
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Series: | Case Reports in Medicine |
Online Access: | http://dx.doi.org/10.1155/2013/735058 |
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author | Sawad Boonpiyathad Atik Sangasapaviliya |
author_facet | Sawad Boonpiyathad Atik Sangasapaviliya |
author_sort | Sawad Boonpiyathad |
collection | DOAJ |
description | Tracheobronchomalacia (TBM) is defined as the condition where the airway lumen narrows more than 50 percent. The acquired TBM usually occurs in adults; however, the prevalence of TBM in asthma is unknown. We report two cases of severe asthma in elderly patients that could not be controlled with higher medication use. Case 1 was a 70-year-old woman with sever persistent asthma for 10 years, presented with uncontrolled symptoms for 4 months. A CT of the chest showed collapse of the trachea at the posterior wall. Case 2 involved a 72-year-old woman with partly controlled asthma presenting with uncontrolled symptoms for 3 months. A CT of the chest showed normal distal tracheal anteroposterior diameter. However, bronchoscopy showed bronchomalacia at the right and left bronchus of the lower lungs. Patients who have severe asthma, despite adequate treatment with medication, should be further investigated to exclude other diseases that have clinical features similar to asthma such as tracheobronchomalacia, particularly in the elderly. |
format | Article |
id | doaj-art-60e22f6086c044f0ab3a17aada4f749c |
institution | Kabale University |
issn | 1687-9627 1687-9635 |
language | English |
publishDate | 2013-01-01 |
publisher | Wiley |
record_format | Article |
series | Case Reports in Medicine |
spelling | doaj-art-60e22f6086c044f0ab3a17aada4f749c2025-02-03T01:30:27ZengWileyCase Reports in Medicine1687-96271687-96352013-01-01201310.1155/2013/735058735058Refractory Asthma Treatment Is Complicated by Tracheobronchomalacia: Case Reports and Review of the LiteratureSawad Boonpiyathad0Atik Sangasapaviliya1Division of Allergy and Clinical Immunology, Department of Medicine, Phramongkutklao Hospital, Bangkok 10400, ThailandDivision of Allergy and Clinical Immunology, Department of Medicine, Phramongkutklao Hospital, Bangkok 10400, ThailandTracheobronchomalacia (TBM) is defined as the condition where the airway lumen narrows more than 50 percent. The acquired TBM usually occurs in adults; however, the prevalence of TBM in asthma is unknown. We report two cases of severe asthma in elderly patients that could not be controlled with higher medication use. Case 1 was a 70-year-old woman with sever persistent asthma for 10 years, presented with uncontrolled symptoms for 4 months. A CT of the chest showed collapse of the trachea at the posterior wall. Case 2 involved a 72-year-old woman with partly controlled asthma presenting with uncontrolled symptoms for 3 months. A CT of the chest showed normal distal tracheal anteroposterior diameter. However, bronchoscopy showed bronchomalacia at the right and left bronchus of the lower lungs. Patients who have severe asthma, despite adequate treatment with medication, should be further investigated to exclude other diseases that have clinical features similar to asthma such as tracheobronchomalacia, particularly in the elderly.http://dx.doi.org/10.1155/2013/735058 |
spellingShingle | Sawad Boonpiyathad Atik Sangasapaviliya Refractory Asthma Treatment Is Complicated by Tracheobronchomalacia: Case Reports and Review of the Literature Case Reports in Medicine |
title | Refractory Asthma Treatment Is Complicated by Tracheobronchomalacia: Case Reports and Review of the Literature |
title_full | Refractory Asthma Treatment Is Complicated by Tracheobronchomalacia: Case Reports and Review of the Literature |
title_fullStr | Refractory Asthma Treatment Is Complicated by Tracheobronchomalacia: Case Reports and Review of the Literature |
title_full_unstemmed | Refractory Asthma Treatment Is Complicated by Tracheobronchomalacia: Case Reports and Review of the Literature |
title_short | Refractory Asthma Treatment Is Complicated by Tracheobronchomalacia: Case Reports and Review of the Literature |
title_sort | refractory asthma treatment is complicated by tracheobronchomalacia case reports and review of the literature |
url | http://dx.doi.org/10.1155/2013/735058 |
work_keys_str_mv | AT sawadboonpiyathad refractoryasthmatreatmentiscomplicatedbytracheobronchomalaciacasereportsandreviewoftheliterature AT atiksangasapaviliya refractoryasthmatreatmentiscomplicatedbytracheobronchomalaciacasereportsandreviewoftheliterature |