Feasibility, Safety, and Compliance in a Randomized Controlled Trial of Physical Therapy for Parkinson's Disease
Both efficacy and clinical feasibility deserve consideration in translation of research outcomes. This study evaluated the feasibility of rehabilitation programs within the context of a large randomized controlled trial of physical therapy. Ambulant participants with Parkinson's disease (PD) (n...
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| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | Parkinson's Disease |
| Online Access: | http://dx.doi.org/10.1155/2012/795294 |
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| _version_ | 1832563016373108736 |
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| author | Jennifer L. McGinley Clarissa Martin Frances E. Huxham Hylton B. Menz Mary Danoudis Anna T. Murphy Jennifer J. Watts Robert Iansek Meg E. Morris |
| author_facet | Jennifer L. McGinley Clarissa Martin Frances E. Huxham Hylton B. Menz Mary Danoudis Anna T. Murphy Jennifer J. Watts Robert Iansek Meg E. Morris |
| author_sort | Jennifer L. McGinley |
| collection | DOAJ |
| description | Both efficacy and clinical feasibility deserve consideration in translation of research outcomes. This study evaluated the feasibility of rehabilitation programs within the context of a large randomized controlled trial of physical therapy. Ambulant participants with Parkinson's disease (PD) (n=210) were randomized into three groups: (1) progressive strength training (PST); (2) movement strategy training (MST); or (3) control (“life skills”). PST and MST included fall prevention education. Feasibility was evaluated in terms of safety, retention, adherence, and compliance measures. Time to first fall during the intervention phase did not differ across groups, and adverse effects were minimal. Retention was high; only eight participants withdrew during or after the intervention phase. Strong adherence (attendance >80%) did not differ between groups (P=.435). Compliance in the therapy groups was high. All three programs proved feasible, suggesting they may be safely implemented for people with PD in community-based clinical practice. |
| format | Article |
| id | doaj-art-60da5470946943fc8db3c425e3155499 |
| institution | Kabale University |
| issn | 2090-8083 2042-0080 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Parkinson's Disease |
| spelling | doaj-art-60da5470946943fc8db3c425e31554992025-02-03T01:21:08ZengWileyParkinson's Disease2090-80832042-00802012-01-01201210.1155/2012/795294795294Feasibility, Safety, and Compliance in a Randomized Controlled Trial of Physical Therapy for Parkinson's DiseaseJennifer L. McGinley0Clarissa Martin1Frances E. Huxham2Hylton B. Menz3Mary Danoudis4Anna T. Murphy5Jennifer J. Watts6Robert Iansek7Meg E. Morris8Melbourne School of Health Sciences, Physiotherapy, The University of Melbourne, Carlton, VIC 3010, AustraliaMelbourne School of Health Sciences, Physiotherapy, The University of Melbourne, Carlton, VIC 3010, AustraliaMelbourne School of Health Sciences, Physiotherapy, The University of Melbourne, Carlton, VIC 3010, AustraliaMusculoskeletal Research Centre, Faculty of Health Sciences, La Trobe University, Bundoora, VIC 3086, AustraliaMelbourne School of Health Sciences, Physiotherapy, The University of Melbourne, Carlton, VIC 3010, AustraliaMelbourne School of Health Sciences, Physiotherapy, The University of Melbourne, Carlton, VIC 3010, AustraliaMelbourne School of Health Sciences, Physiotherapy, The University of Melbourne, Carlton, VIC 3010, AustraliaNational Parkinson Foundation Center of Excellence, Clinical Research Centre for Movement Disorders and Gait and Victorian Comprehensive Parkinson's Program, Kingston Centre, Warrigal Road, Cheltenham, VIC 3192, AustraliaMelbourne School of Health Sciences, Physiotherapy, The University of Melbourne, Carlton, VIC 3010, AustraliaBoth efficacy and clinical feasibility deserve consideration in translation of research outcomes. This study evaluated the feasibility of rehabilitation programs within the context of a large randomized controlled trial of physical therapy. Ambulant participants with Parkinson's disease (PD) (n=210) were randomized into three groups: (1) progressive strength training (PST); (2) movement strategy training (MST); or (3) control (“life skills”). PST and MST included fall prevention education. Feasibility was evaluated in terms of safety, retention, adherence, and compliance measures. Time to first fall during the intervention phase did not differ across groups, and adverse effects were minimal. Retention was high; only eight participants withdrew during or after the intervention phase. Strong adherence (attendance >80%) did not differ between groups (P=.435). Compliance in the therapy groups was high. All three programs proved feasible, suggesting they may be safely implemented for people with PD in community-based clinical practice.http://dx.doi.org/10.1155/2012/795294 |
| spellingShingle | Jennifer L. McGinley Clarissa Martin Frances E. Huxham Hylton B. Menz Mary Danoudis Anna T. Murphy Jennifer J. Watts Robert Iansek Meg E. Morris Feasibility, Safety, and Compliance in a Randomized Controlled Trial of Physical Therapy for Parkinson's Disease Parkinson's Disease |
| title | Feasibility, Safety, and Compliance in a Randomized Controlled Trial of Physical Therapy for Parkinson's Disease |
| title_full | Feasibility, Safety, and Compliance in a Randomized Controlled Trial of Physical Therapy for Parkinson's Disease |
| title_fullStr | Feasibility, Safety, and Compliance in a Randomized Controlled Trial of Physical Therapy for Parkinson's Disease |
| title_full_unstemmed | Feasibility, Safety, and Compliance in a Randomized Controlled Trial of Physical Therapy for Parkinson's Disease |
| title_short | Feasibility, Safety, and Compliance in a Randomized Controlled Trial of Physical Therapy for Parkinson's Disease |
| title_sort | feasibility safety and compliance in a randomized controlled trial of physical therapy for parkinson s disease |
| url | http://dx.doi.org/10.1155/2012/795294 |
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