RET fusion driven (RETfus+) non-small cell lung cancer: a comprehensive genomic profiling study with histologic correlation

RET fusion driven (RETfus+) non-small cell lung cancer: a comprehensive genomic profiling study with histologic correlation

BackgroundFusion of the RET gene resulting in clinically significant Genomic Alteration (GA) occur in 1-2% of NSCLC in the United States and has emerged as a major target for RET inhibitors which are first line treatment options in the Stage 4 setting. RET fusions have also been well-described as ac...

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Bibliographic Details
Main Authors: Prashanth Ashok Kumar, Michael Connolly, Alina Basnet, Dean Pavlick, Richard Huang, Steven Graziano, Jeffrey Ross
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Oncology
Subjects:
non-small cell lung cancer
RET fusion
targeted therapy
genomic profiling
lung cancer
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1477910/full
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