Anti-Quorum Sensing in Pathogenic Microbes Using Plant-Based Bioactive Phytochemicals

Infectious disease-causing pathogenic microorganisms grow rapidly within quorum sensing mediated biofilms. Attempts are made to restrict quorum sensing in pathogens, and the formation of biofilms has paved the way for the identification of bioactive phytochemicals. Anti-QS compounds have been proven...

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Main Authors: Kumaran Subramanian, Harshni Selvaraj, Balakrishnan K, Pugazhvendan Sampath Renuga, Velmurugan S, Wilson Aruni
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Advances in Materials Science and Engineering
Online Access:http://dx.doi.org/10.1155/2022/7532086
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author Kumaran Subramanian
Harshni Selvaraj
Balakrishnan K
Pugazhvendan Sampath Renuga
Velmurugan S
Wilson Aruni
author_facet Kumaran Subramanian
Harshni Selvaraj
Balakrishnan K
Pugazhvendan Sampath Renuga
Velmurugan S
Wilson Aruni
author_sort Kumaran Subramanian
collection DOAJ
description Infectious disease-causing pathogenic microorganisms grow rapidly within quorum sensing mediated biofilms. Attempts are made to restrict quorum sensing in pathogens, and the formation of biofilms has paved the way for the identification of bioactive phytochemicals. Anti-QS compounds have been proven to reduce bacterial pathogenicity in the past. Medicinal plants provide an enticing repertoire of phytochemicals with distinct microbial disease-controlling potential due to the vast spectrum of secondary metabolites included in extracts such as phenolics, quinones, flavonoids, alkaloids, terpenoids, and polyacetylenes. This review makes a specialty of the bioactive molecules produced using vegetation which have a target closer to quorum sensing accompanied via biofilm formation in pathogenic microbes.
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institution Kabale University
issn 1687-8442
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publishDate 2022-01-01
publisher Wiley
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spelling doaj-art-60b0070d214148138eca15f7261fc0af2025-02-03T01:02:14ZengWileyAdvances in Materials Science and Engineering1687-84422022-01-01202210.1155/2022/7532086Anti-Quorum Sensing in Pathogenic Microbes Using Plant-Based Bioactive PhytochemicalsKumaran Subramanian0Harshni Selvaraj1Balakrishnan K2Pugazhvendan Sampath Renuga3Velmurugan S4Wilson Aruni5Centre for Drug Discovery and DevelopmentDepartment of BiotechnologyDepartment of ZoologyDepartment of ZoologyDepartment of BiologyLoma Linda Veteran AffairsInfectious disease-causing pathogenic microorganisms grow rapidly within quorum sensing mediated biofilms. Attempts are made to restrict quorum sensing in pathogens, and the formation of biofilms has paved the way for the identification of bioactive phytochemicals. Anti-QS compounds have been proven to reduce bacterial pathogenicity in the past. Medicinal plants provide an enticing repertoire of phytochemicals with distinct microbial disease-controlling potential due to the vast spectrum of secondary metabolites included in extracts such as phenolics, quinones, flavonoids, alkaloids, terpenoids, and polyacetylenes. This review makes a specialty of the bioactive molecules produced using vegetation which have a target closer to quorum sensing accompanied via biofilm formation in pathogenic microbes.http://dx.doi.org/10.1155/2022/7532086
spellingShingle Kumaran Subramanian
Harshni Selvaraj
Balakrishnan K
Pugazhvendan Sampath Renuga
Velmurugan S
Wilson Aruni
Anti-Quorum Sensing in Pathogenic Microbes Using Plant-Based Bioactive Phytochemicals
Advances in Materials Science and Engineering
title Anti-Quorum Sensing in Pathogenic Microbes Using Plant-Based Bioactive Phytochemicals
title_full Anti-Quorum Sensing in Pathogenic Microbes Using Plant-Based Bioactive Phytochemicals
title_fullStr Anti-Quorum Sensing in Pathogenic Microbes Using Plant-Based Bioactive Phytochemicals
title_full_unstemmed Anti-Quorum Sensing in Pathogenic Microbes Using Plant-Based Bioactive Phytochemicals
title_short Anti-Quorum Sensing in Pathogenic Microbes Using Plant-Based Bioactive Phytochemicals
title_sort anti quorum sensing in pathogenic microbes using plant based bioactive phytochemicals
url http://dx.doi.org/10.1155/2022/7532086
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