A Narrative Review on the Pathophysiology and Management for Radiation Cystitis

Radiation cystitis is a recognised complication of pelvic radiotherapy. Incidence of radiation cystitis ranges from 23 to 80% and the incidence of severe haematuria ranges from 5 to 8%. High quality data on management strategies for radiation cystitis is sparse. Treatment modalities are subclassifie...

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Main Authors: C. Browne, N. F. Davis, E. Mac Craith, G. M. Lennon, D. W. Mulvin, D. M. Quinlan, Gerard P. Mc Vey, D. J. Galvin
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Advances in Urology
Online Access:http://dx.doi.org/10.1155/2015/346812
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author C. Browne
N. F. Davis
E. Mac Craith
G. M. Lennon
D. W. Mulvin
D. M. Quinlan
Gerard P. Mc Vey
D. J. Galvin
author_facet C. Browne
N. F. Davis
E. Mac Craith
G. M. Lennon
D. W. Mulvin
D. M. Quinlan
Gerard P. Mc Vey
D. J. Galvin
author_sort C. Browne
collection DOAJ
description Radiation cystitis is a recognised complication of pelvic radiotherapy. Incidence of radiation cystitis ranges from 23 to 80% and the incidence of severe haematuria ranges from 5 to 8%. High quality data on management strategies for radiation cystitis is sparse. Treatment modalities are subclassified into systemic therapies, intravesical therapies, and hyperbaric oxygen and interventional procedures. Short-term cure rates range from 76 to 95% for hyperbaric oxygen therapy and interventional procedures. Adverse effects of these treatment strategies are acceptable. Ultimately, most patients require multimodal treatment for curative purposes. Large randomised trials exploring emergent management strategies are required in order to strengthen evidence-based treatment strategies. Urologists encounter radiation cystitis commonly and should be familiar with diagnostic modalities and treatment strategies.
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institution Kabale University
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language English
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series Advances in Urology
spelling doaj-art-60a07de151194da89e14fa4cff4ffeb22025-02-03T06:14:19ZengWileyAdvances in Urology1687-63691687-63772015-01-01201510.1155/2015/346812346812A Narrative Review on the Pathophysiology and Management for Radiation CystitisC. Browne0N. F. Davis1E. Mac Craith2G. M. Lennon3D. W. Mulvin4D. M. Quinlan5Gerard P. Mc Vey6D. J. Galvin7Department of Urology, St. Vincent’s University Hospital, Dublin 4, IrelandDepartment of Urology, St. Vincent’s University Hospital, Dublin 4, IrelandDepartment of Urology, St. Vincent’s University Hospital, Dublin 4, IrelandDepartment of Urology, St. Vincent’s University Hospital, Dublin 4, IrelandDepartment of Urology, St. Vincent’s University Hospital, Dublin 4, IrelandDepartment of Urology, St. Vincent’s University Hospital, Dublin 4, IrelandDepartment of Radiation Oncology, St. Vincent’s University Hospital, Dublin 4, IrelandDepartment of Urology, St. Vincent’s University Hospital, Dublin 4, IrelandRadiation cystitis is a recognised complication of pelvic radiotherapy. Incidence of radiation cystitis ranges from 23 to 80% and the incidence of severe haematuria ranges from 5 to 8%. High quality data on management strategies for radiation cystitis is sparse. Treatment modalities are subclassified into systemic therapies, intravesical therapies, and hyperbaric oxygen and interventional procedures. Short-term cure rates range from 76 to 95% for hyperbaric oxygen therapy and interventional procedures. Adverse effects of these treatment strategies are acceptable. Ultimately, most patients require multimodal treatment for curative purposes. Large randomised trials exploring emergent management strategies are required in order to strengthen evidence-based treatment strategies. Urologists encounter radiation cystitis commonly and should be familiar with diagnostic modalities and treatment strategies.http://dx.doi.org/10.1155/2015/346812
spellingShingle C. Browne
N. F. Davis
E. Mac Craith
G. M. Lennon
D. W. Mulvin
D. M. Quinlan
Gerard P. Mc Vey
D. J. Galvin
A Narrative Review on the Pathophysiology and Management for Radiation Cystitis
Advances in Urology
title A Narrative Review on the Pathophysiology and Management for Radiation Cystitis
title_full A Narrative Review on the Pathophysiology and Management for Radiation Cystitis
title_fullStr A Narrative Review on the Pathophysiology and Management for Radiation Cystitis
title_full_unstemmed A Narrative Review on the Pathophysiology and Management for Radiation Cystitis
title_short A Narrative Review on the Pathophysiology and Management for Radiation Cystitis
title_sort narrative review on the pathophysiology and management for radiation cystitis
url http://dx.doi.org/10.1155/2015/346812
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