Previous treatment decreases efficacy of pralsetinib in RET fusion-positive non-small-cell lung cancer

Previous treatment decreases efficacy of pralsetinib in RET fusion-positive non-small-cell lung cancer

BackgroundPralsetinib is a selective RET inhibitor. The ARROW trial revealed that RET fusion-positive non-small-cell lung cancer (NSCLC) can benefit from pralsetinib with tolerable adverse events (AEs). However, the efficacy and safety of pralsetinib in real world has rarely been reported.Materials...

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Bibliographic Details
Main Authors: Lei Wang, Yafei You, Wenzhuo He, Yu Hou, Lan Li, Li Wang, Chang Jiang, Jiahong Yi, Yaoxiong Xia, Liangping Xia
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Medicine
Subjects:
RET fusion
non-small-cell lung cancer
pralsetinib
survival outcomes
prognostic factors
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2025.1467871/full
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