Medical Cannabis for Chronic Noncancer Pain: A Systematic Review of Health Care Recommendations

Purpose. Medical cannabis for patients with chronic noncancer pain (CNCP) has been the focus of numerous health care recommendations. We conducted a systematic review to identify and summarize the currently available evidence-based recommendations. Methods. We searched MEDLINE, EMBASE, PsycINFO, the...

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Main Authors: Yaping Chang, Meng Zhu, Christopher Vannabouathong, Raman Mundi, Roland S. Chou, Mohit Bhandari
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Pain Research and Management
Online Access:http://dx.doi.org/10.1155/2021/8857948
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author Yaping Chang
Meng Zhu
Christopher Vannabouathong
Raman Mundi
Roland S. Chou
Mohit Bhandari
author_facet Yaping Chang
Meng Zhu
Christopher Vannabouathong
Raman Mundi
Roland S. Chou
Mohit Bhandari
author_sort Yaping Chang
collection DOAJ
description Purpose. Medical cannabis for patients with chronic noncancer pain (CNCP) has been the focus of numerous health care recommendations. We conducted a systematic review to identify and summarize the currently available evidence-based recommendations. Methods. We searched MEDLINE, EMBASE, PsycINFO, the Cochrane database of systematic reviews, and websites for clinical guidelines and recommendations. We summarized the type of the publications, developers, approach of health care recommendation development, year and country of publication, and conditions that were addressed. We categorized the direction and strength of each recommendation. Results. We identified 12 eligible publications. Publication years ranged from 2007 to 2019; four (33.3%) of them were published in 2018. Canada ranked first for the number of publications (n = 4, 33.3%). Most (n = 11, 92%) of the included recommendations were based on both a systematic review of the best evidence and expert consensus. All the included publications provided a recommendation supporting medical cannabis for CNCP in general and for the specific conditions of neuropathic pain, chronic pain in people living with Human Immunodeficiency Virus (HIV), and chronic abdominal pain, with detailed information sharing and comprehensive consideration of a patient’s own values and preferences. Conclusion. Clinicians can attend to the guidance currently offered, being aware that only weak recommendations are available for medical cannabis in patients with CNCP, as a third- or fourth-line therapy. Detailed discussions with patients regarding the benefits in reducing pain and potential adverse effects are required before its prescription.
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spelling doaj-art-606bfdf07e7f4720916e4134f7515d732025-02-03T06:05:43ZengWileyPain Research and Management1203-67651918-15232021-01-01202110.1155/2021/88579488857948Medical Cannabis for Chronic Noncancer Pain: A Systematic Review of Health Care RecommendationsYaping Chang0Meng Zhu1Christopher Vannabouathong2Raman Mundi3Roland S. Chou4Mohit Bhandari5OrthoEvidence Inc., Burlington, ON, CanadaOrthoEvidence Inc., Burlington, ON, CanadaOrthoEvidence Inc., Burlington, ON, CanadaDepartment of Surgery, University of Toronto, Toronto, ON, CanadaFaculty of Health Sciences, McMaster University, Hamilton, ON, CanadaOrthoEvidence Inc., Burlington, ON, CanadaPurpose. Medical cannabis for patients with chronic noncancer pain (CNCP) has been the focus of numerous health care recommendations. We conducted a systematic review to identify and summarize the currently available evidence-based recommendations. Methods. We searched MEDLINE, EMBASE, PsycINFO, the Cochrane database of systematic reviews, and websites for clinical guidelines and recommendations. We summarized the type of the publications, developers, approach of health care recommendation development, year and country of publication, and conditions that were addressed. We categorized the direction and strength of each recommendation. Results. We identified 12 eligible publications. Publication years ranged from 2007 to 2019; four (33.3%) of them were published in 2018. Canada ranked first for the number of publications (n = 4, 33.3%). Most (n = 11, 92%) of the included recommendations were based on both a systematic review of the best evidence and expert consensus. All the included publications provided a recommendation supporting medical cannabis for CNCP in general and for the specific conditions of neuropathic pain, chronic pain in people living with Human Immunodeficiency Virus (HIV), and chronic abdominal pain, with detailed information sharing and comprehensive consideration of a patient’s own values and preferences. Conclusion. Clinicians can attend to the guidance currently offered, being aware that only weak recommendations are available for medical cannabis in patients with CNCP, as a third- or fourth-line therapy. Detailed discussions with patients regarding the benefits in reducing pain and potential adverse effects are required before its prescription.http://dx.doi.org/10.1155/2021/8857948
spellingShingle Yaping Chang
Meng Zhu
Christopher Vannabouathong
Raman Mundi
Roland S. Chou
Mohit Bhandari
Medical Cannabis for Chronic Noncancer Pain: A Systematic Review of Health Care Recommendations
Pain Research and Management
title Medical Cannabis for Chronic Noncancer Pain: A Systematic Review of Health Care Recommendations
title_full Medical Cannabis for Chronic Noncancer Pain: A Systematic Review of Health Care Recommendations
title_fullStr Medical Cannabis for Chronic Noncancer Pain: A Systematic Review of Health Care Recommendations
title_full_unstemmed Medical Cannabis for Chronic Noncancer Pain: A Systematic Review of Health Care Recommendations
title_short Medical Cannabis for Chronic Noncancer Pain: A Systematic Review of Health Care Recommendations
title_sort medical cannabis for chronic noncancer pain a systematic review of health care recommendations
url http://dx.doi.org/10.1155/2021/8857948
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