Mesotherapy: From Historical Notes to Scientific Evidence and Future Prospects
Intradermal therapy, known as mesotherapy, is a technique used to inject a drug into the surface layer of the skin. In particular, it involves the use of a short needle to deposit the drug in the dermis. The intradermal microdeposit modulates the drug’s kinetics, slowing absorption and prolonging th...
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| Language: | English |
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2020-01-01
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| Series: | The Scientific World Journal |
| Online Access: | http://dx.doi.org/10.1155/2020/3542848 |
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| author | Massimo Mammucari Enrica Maggiori Domenico Russo Chiara Giorgio Gianpaolo Ronconi Paola E Ferrara Flora Canzona Luciano Antonaci Bartolomeo Violo Renato Vellucci Domenico Rocco Mediati Alberto Migliore Umberto Massafra Barbara Bifarini Fabio Gori Massimo di Carlo Stefano Brauneis Teresa Paolucci Piergiovanni Rocchi Anna Cuguttu Raffaele Di Marzo Alessandro Bomprezzi Stefania Santini Manuela Giardini Anna Rosa Catizzone Fiammetta Troili Dario Dorato Alessandra Gallo Costanza Guglielmo Silvia Natoli |
| author_facet | Massimo Mammucari Enrica Maggiori Domenico Russo Chiara Giorgio Gianpaolo Ronconi Paola E Ferrara Flora Canzona Luciano Antonaci Bartolomeo Violo Renato Vellucci Domenico Rocco Mediati Alberto Migliore Umberto Massafra Barbara Bifarini Fabio Gori Massimo di Carlo Stefano Brauneis Teresa Paolucci Piergiovanni Rocchi Anna Cuguttu Raffaele Di Marzo Alessandro Bomprezzi Stefania Santini Manuela Giardini Anna Rosa Catizzone Fiammetta Troili Dario Dorato Alessandra Gallo Costanza Guglielmo Silvia Natoli |
| author_sort | Massimo Mammucari |
| collection | DOAJ |
| description | Intradermal therapy, known as mesotherapy, is a technique used to inject a drug into the surface layer of the skin. In particular, it involves the use of a short needle to deposit the drug in the dermis. The intradermal microdeposit modulates the drug’s kinetics, slowing absorption and prolonging the local mechanism of action. It is successfully applied in the treatment of some forms of localized pain syndromes and other local clinical conditions. It could be suggested when a systemic drug-sparing effect is useful, when other therapies have failed (or cannot be used), and when it can synergize with other pharmacological or nonpharmacological therapies. Despite the lack of randomized clinical trials in some fields of application, a general consensus is also reached in nonpharmacological mechanism of action, the technique execution modalities, the scientific rationale to apply it in some indications, and the usefulness of the informed consent. The Italian Mesotherapy Society proposes this position paper to apply intradermal therapy based on scientific evidence and no longer on personal bias. |
| format | Article |
| id | doaj-art-6036f267c3fb47b99f34937a9faefa55 |
| institution | Kabale University |
| issn | 2356-6140 1537-744X |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | The Scientific World Journal |
| spelling | doaj-art-6036f267c3fb47b99f34937a9faefa552025-02-03T06:43:28ZengWileyThe Scientific World Journal2356-61401537-744X2020-01-01202010.1155/2020/35428483542848Mesotherapy: From Historical Notes to Scientific Evidence and Future ProspectsMassimo Mammucari0Enrica Maggiori1Domenico Russo2Chiara Giorgio3Gianpaolo Ronconi4Paola E Ferrara5Flora Canzona6Luciano Antonaci7Bartolomeo Violo8Renato Vellucci9Domenico Rocco Mediati10Alberto Migliore11Umberto Massafra12Barbara Bifarini13Fabio Gori14Massimo di Carlo15Stefano Brauneis16Teresa Paolucci17Piergiovanni Rocchi18Anna Cuguttu19Raffaele Di Marzo20Alessandro Bomprezzi21Stefania Santini22Manuela Giardini23Anna Rosa Catizzone24Fiammetta Troili25Dario Dorato26Alessandra Gallo27Costanza Guglielmo28Silvia Natoli29Primary Care Unit ASL RM 1, Rome, ItalyPrimary Care Unit ASL RM 1, Rome, Italy“San Marco” Hospice and Palliative Care, Latina, ItalyRehabilitation Unit, F Pirinei Hospital, Altamura, BA, ItalyPhysical Medicine and Rehabilitation Unit, IRCCS, Catholic University of Sacred Heart, Rome, ItalyPhysical Medicine and Rehabilitation Unit, IRCCS, Catholic University of Sacred Heart, Rome, ItalyIstituto Dermopatico Dell’Immacolata, IRCCS Foundation, Rome, ItalyPrimary Care Unit ASL RM 1, Rome, ItalyPain Therapy Unit, S. Spirito Hospital, Rome, ItalyPalliative Care and Pain Therapy Unit – Anesthesiology and Resuscitation Department of Careggi University Hospital, Florence, ItalyPalliative Care and Pain Therapy Unit – Anesthesiology and Resuscitation Department of Careggi University Hospital, Florence, ItalyUnit of Rheumatology, San Pietro Fatebenefratelli Hospital, Rome, ItalyUnit of Rheumatology, San Pietro Fatebenefratelli Hospital, Rome, ItalySection of Anesthesia, Intensive Care, and Pain Medicine, Azienda Ospedaliera-Universitaria Santa Maria Della Misericordia, Perugia, ItalySection of Anesthesia, Intensive Care, and Pain Medicine, Azienda Ospedaliera-Universitaria Santa Maria Della Misericordia, Perugia, ItalyPain Therapy Unit, S Pertini Hospital, Rome, ItalyPain Center “Enzo Borzomati”, University Hospital of Rome “Policlinico Umberto I”, Rome, ItalyUniversity G. D’Annunzio Chieti, Department of Medical and Oral Sciences and Biotechnologies, Chieti-Pescara, ItalyMember of the Italian Society of Mesotherapy, Rome, ItalyMember of the Italian Society of Mesotherapy, Rome, ItalyMember of the Italian Society of Mesotherapy, Rome, ItalyMember of the Italian Society of Mesotherapy, Rome, ItalyMember of the Italian Society of Mesotherapy, Rome, ItalyMember of the Italian Society of Mesotherapy, Rome, ItalyMember of the Italian Society of Mesotherapy, Rome, ItalyMember of the Italian Society of Mesotherapy, Rome, ItalyMember of the Italian Society of Mesotherapy, Rome, ItalyMember of the Italian Society of Mesotherapy, Rome, ItalyMember of the Italian Society of Mesotherapy, Rome, ItalyDepartment of Clinical Science and Translational Medicine, Tor Vergata University, Rome, ItalyIntradermal therapy, known as mesotherapy, is a technique used to inject a drug into the surface layer of the skin. In particular, it involves the use of a short needle to deposit the drug in the dermis. The intradermal microdeposit modulates the drug’s kinetics, slowing absorption and prolonging the local mechanism of action. It is successfully applied in the treatment of some forms of localized pain syndromes and other local clinical conditions. It could be suggested when a systemic drug-sparing effect is useful, when other therapies have failed (or cannot be used), and when it can synergize with other pharmacological or nonpharmacological therapies. Despite the lack of randomized clinical trials in some fields of application, a general consensus is also reached in nonpharmacological mechanism of action, the technique execution modalities, the scientific rationale to apply it in some indications, and the usefulness of the informed consent. The Italian Mesotherapy Society proposes this position paper to apply intradermal therapy based on scientific evidence and no longer on personal bias.http://dx.doi.org/10.1155/2020/3542848 |
| spellingShingle | Massimo Mammucari Enrica Maggiori Domenico Russo Chiara Giorgio Gianpaolo Ronconi Paola E Ferrara Flora Canzona Luciano Antonaci Bartolomeo Violo Renato Vellucci Domenico Rocco Mediati Alberto Migliore Umberto Massafra Barbara Bifarini Fabio Gori Massimo di Carlo Stefano Brauneis Teresa Paolucci Piergiovanni Rocchi Anna Cuguttu Raffaele Di Marzo Alessandro Bomprezzi Stefania Santini Manuela Giardini Anna Rosa Catizzone Fiammetta Troili Dario Dorato Alessandra Gallo Costanza Guglielmo Silvia Natoli Mesotherapy: From Historical Notes to Scientific Evidence and Future Prospects The Scientific World Journal |
| title | Mesotherapy: From Historical Notes to Scientific Evidence and Future Prospects |
| title_full | Mesotherapy: From Historical Notes to Scientific Evidence and Future Prospects |
| title_fullStr | Mesotherapy: From Historical Notes to Scientific Evidence and Future Prospects |
| title_full_unstemmed | Mesotherapy: From Historical Notes to Scientific Evidence and Future Prospects |
| title_short | Mesotherapy: From Historical Notes to Scientific Evidence and Future Prospects |
| title_sort | mesotherapy from historical notes to scientific evidence and future prospects |
| url | http://dx.doi.org/10.1155/2020/3542848 |
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