Increased Expression of Visfatin in Monocytes and Macrophages in Male Acute Myocardial Infarction Patients

We demonstrated that visfatin expressed in monocytes and neutrophils and increased their reactivity in male acute ST-segment elevation myocardial infarction patients. Furthermore, visfatin was strongly appeared in lipid rich coronary rupture plaques and macrophages. These results suggest another exp...

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Main Authors: Cheng-An Chiu, Teng-Hung Yu, Wei-Chin Hung, Li-Fen Lu, Fu-Mei Chung, I-Ting Tsai, Chih-Ying Yang, Chia-Chang Hsu, Yung-Chuan Lu, Jer-Yiing Houng, Yau-Jiunn Lee, Chao-Ping Wang
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2012/469852
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author Cheng-An Chiu
Teng-Hung Yu
Wei-Chin Hung
Li-Fen Lu
Fu-Mei Chung
I-Ting Tsai
Chih-Ying Yang
Chia-Chang Hsu
Yung-Chuan Lu
Jer-Yiing Houng
Yau-Jiunn Lee
Chao-Ping Wang
author_facet Cheng-An Chiu
Teng-Hung Yu
Wei-Chin Hung
Li-Fen Lu
Fu-Mei Chung
I-Ting Tsai
Chih-Ying Yang
Chia-Chang Hsu
Yung-Chuan Lu
Jer-Yiing Houng
Yau-Jiunn Lee
Chao-Ping Wang
author_sort Cheng-An Chiu
collection DOAJ
description We demonstrated that visfatin expressed in monocytes and neutrophils and increased their reactivity in male acute ST-segment elevation myocardial infarction patients. Furthermore, visfatin was strongly appeared in lipid rich coronary rupture plaques and macrophages. These results suggest another explanation about leukocytes mediated visfatin that may play a pathogenesis role in coronary vulnerable plaques rupture.
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institution Kabale University
issn 0962-9351
1466-1861
language English
publishDate 2012-01-01
publisher Wiley
record_format Article
series Mediators of Inflammation
spelling doaj-art-601b65df26fa4f25b2202a7c315793842025-02-03T05:46:30ZengWileyMediators of Inflammation0962-93511466-18612012-01-01201210.1155/2012/469852469852Increased Expression of Visfatin in Monocytes and Macrophages in Male Acute Myocardial Infarction PatientsCheng-An Chiu0Teng-Hung Yu1Wei-Chin Hung2Li-Fen Lu3Fu-Mei Chung4I-Ting Tsai5Chih-Ying Yang6Chia-Chang Hsu7Yung-Chuan Lu8Jer-Yiing Houng9Yau-Jiunn Lee10Chao-Ping Wang11Division of Cardiology, Department of Internal Medicine, E-Da Hospital, I-Shou University, No. 1 Yi-Da Road, Jiau-Shu Village, Yan-Chao District, Kaohsiung 82445, TaiwanDivision of Cardiology, Department of Internal Medicine, E-Da Hospital, I-Shou University, No. 1 Yi-Da Road, Jiau-Shu Village, Yan-Chao District, Kaohsiung 82445, TaiwanDivision of Cardiology, Department of Internal Medicine, E-Da Hospital, I-Shou University, No. 1 Yi-Da Road, Jiau-Shu Village, Yan-Chao District, Kaohsiung 82445, TaiwanDivision of Cardiac Surgery, Department of Surgery, E-Da Hospital, I-Shou University, No. 1 Yi-Da Road, Jiau-Shu Village, Yan-Chao District, Kaohsiung 82445, TaiwanDivision of Cardiology, Department of Internal Medicine, E-Da Hospital, I-Shou University, No. 1 Yi-Da Road, Jiau-Shu Village, Yan-Chao District, Kaohsiung 82445, TaiwanDepartment of Emergency, E-Da Hospital, I-Shou University, No. 1 Yi-Da Road, Jiau-Shu Village, Yan-Chao District, Kaohsiung 82445, TaiwanDepartment of Emergency, E-Da Hospital, I-Shou University, No. 1 Yi-Da Road, Jiau-Shu Village, Yan-Chao District, Kaohsiung 82445, TaiwanDivision of Gastroenterology and Hepatology, Department of Internal Medicine, E-Da Hospital, I-Shou University, No. 1 Yi-Da Road, Jiau-Shu Village, Yan-Chao District, Kaohsiung 82445, TaiwanDivision of Endocrinology and Metabolism, Department of Internal Medicine, E-Da Hospital, I-Shou University, No. 1 Yi-Da Road, Jiau-Shu Village, Yan-Chao District, Kaohsiung 82445, TaiwanDepartment of Medical Nutrition, Institute of Biotechnology and Chemical Engineering, I-Shou University, No. 6 Yi-Da Road, Jiau-Shu Village, Yan-Chao District, Kaohsiung 82445, TaiwanLee’s Endocrinologic Clinic, No. 130 Min-Tzu Road, Pingtung, 90000, TaiwanDivision of Cardiology, Department of Internal Medicine, E-Da Hospital, I-Shou University, No. 1 Yi-Da Road, Jiau-Shu Village, Yan-Chao District, Kaohsiung 82445, TaiwanWe demonstrated that visfatin expressed in monocytes and neutrophils and increased their reactivity in male acute ST-segment elevation myocardial infarction patients. Furthermore, visfatin was strongly appeared in lipid rich coronary rupture plaques and macrophages. These results suggest another explanation about leukocytes mediated visfatin that may play a pathogenesis role in coronary vulnerable plaques rupture.http://dx.doi.org/10.1155/2012/469852
spellingShingle Cheng-An Chiu
Teng-Hung Yu
Wei-Chin Hung
Li-Fen Lu
Fu-Mei Chung
I-Ting Tsai
Chih-Ying Yang
Chia-Chang Hsu
Yung-Chuan Lu
Jer-Yiing Houng
Yau-Jiunn Lee
Chao-Ping Wang
Increased Expression of Visfatin in Monocytes and Macrophages in Male Acute Myocardial Infarction Patients
Mediators of Inflammation
title Increased Expression of Visfatin in Monocytes and Macrophages in Male Acute Myocardial Infarction Patients
title_full Increased Expression of Visfatin in Monocytes and Macrophages in Male Acute Myocardial Infarction Patients
title_fullStr Increased Expression of Visfatin in Monocytes and Macrophages in Male Acute Myocardial Infarction Patients
title_full_unstemmed Increased Expression of Visfatin in Monocytes and Macrophages in Male Acute Myocardial Infarction Patients
title_short Increased Expression of Visfatin in Monocytes and Macrophages in Male Acute Myocardial Infarction Patients
title_sort increased expression of visfatin in monocytes and macrophages in male acute myocardial infarction patients
url http://dx.doi.org/10.1155/2012/469852
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