Near-Miss Diagnoses of Solitary Bladder Tumors Highlight the Importance of Immunohistochemical Staining

We report three cases of prostate adenocarcinoma appearing as bladder masses and misdiagnosed as muscle-invasive bladder cancer (MIBC). Patients were referred for consideration for radical cystectomy after initial pathological diagnosis suggested poorly differentiated bladder cancer. Pathological re...

Full description

Saved in:
Bibliographic Details
Main Authors: Van Schloegel, Syed M. Alam, Katie Dennis, Jeffrey Holzbeierlein, John A. Taylor III
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Case Reports in Urology
Online Access:http://dx.doi.org/10.1155/2020/8855451
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832560036429168640
author Van Schloegel
Syed M. Alam
Katie Dennis
Jeffrey Holzbeierlein
John A. Taylor III
author_facet Van Schloegel
Syed M. Alam
Katie Dennis
Jeffrey Holzbeierlein
John A. Taylor III
author_sort Van Schloegel
collection DOAJ
description We report three cases of prostate adenocarcinoma appearing as bladder masses and misdiagnosed as muscle-invasive bladder cancer (MIBC). Patients were referred for consideration for radical cystectomy after initial pathological diagnosis suggested poorly differentiated bladder cancer. Pathological review of tissue samples and subsequent immunohistochemical (IHC) staining confirmed advanced prostatic adenocarcinoma. Systemic therapy for prostate cancer was then initiated. These cases highlight the importance of patient history, physical exam, and IHC staining in consideration of a bladder mass, as these patients may have been subject to undue morbidity and surgical intervention without accurate pathologic diagnosis.
format Article
id doaj-art-6017c17267a94008a78704df01c272ba
institution Kabale University
issn 2090-696X
2090-6978
language English
publishDate 2020-01-01
publisher Wiley
record_format Article
series Case Reports in Urology
spelling doaj-art-6017c17267a94008a78704df01c272ba2025-02-03T01:28:29ZengWileyCase Reports in Urology2090-696X2090-69782020-01-01202010.1155/2020/88554518855451Near-Miss Diagnoses of Solitary Bladder Tumors Highlight the Importance of Immunohistochemical StainingVan Schloegel0Syed M. Alam1Katie Dennis2Jeffrey Holzbeierlein3John A. Taylor III4Department of Urology, University of Kansas Health System, 3901 Rainbow Boulevard, Kansas City, KS 66160, USADepartment of Urology, University of Kansas Health System, 3901 Rainbow Boulevard, Kansas City, KS 66160, USADepartment of Urology, University of Kansas Health System, 3901 Rainbow Boulevard, Kansas City, KS 66160, USADepartment of Urology, University of Kansas Health System, 3901 Rainbow Boulevard, Kansas City, KS 66160, USADepartment of Urology, University of Kansas Health System, 3901 Rainbow Boulevard, Kansas City, KS 66160, USAWe report three cases of prostate adenocarcinoma appearing as bladder masses and misdiagnosed as muscle-invasive bladder cancer (MIBC). Patients were referred for consideration for radical cystectomy after initial pathological diagnosis suggested poorly differentiated bladder cancer. Pathological review of tissue samples and subsequent immunohistochemical (IHC) staining confirmed advanced prostatic adenocarcinoma. Systemic therapy for prostate cancer was then initiated. These cases highlight the importance of patient history, physical exam, and IHC staining in consideration of a bladder mass, as these patients may have been subject to undue morbidity and surgical intervention without accurate pathologic diagnosis.http://dx.doi.org/10.1155/2020/8855451
spellingShingle Van Schloegel
Syed M. Alam
Katie Dennis
Jeffrey Holzbeierlein
John A. Taylor III
Near-Miss Diagnoses of Solitary Bladder Tumors Highlight the Importance of Immunohistochemical Staining
Case Reports in Urology
title Near-Miss Diagnoses of Solitary Bladder Tumors Highlight the Importance of Immunohistochemical Staining
title_full Near-Miss Diagnoses of Solitary Bladder Tumors Highlight the Importance of Immunohistochemical Staining
title_fullStr Near-Miss Diagnoses of Solitary Bladder Tumors Highlight the Importance of Immunohistochemical Staining
title_full_unstemmed Near-Miss Diagnoses of Solitary Bladder Tumors Highlight the Importance of Immunohistochemical Staining
title_short Near-Miss Diagnoses of Solitary Bladder Tumors Highlight the Importance of Immunohistochemical Staining
title_sort near miss diagnoses of solitary bladder tumors highlight the importance of immunohistochemical staining
url http://dx.doi.org/10.1155/2020/8855451
work_keys_str_mv AT vanschloegel nearmissdiagnosesofsolitarybladdertumorshighlighttheimportanceofimmunohistochemicalstaining
AT syedmalam nearmissdiagnosesofsolitarybladdertumorshighlighttheimportanceofimmunohistochemicalstaining
AT katiedennis nearmissdiagnosesofsolitarybladdertumorshighlighttheimportanceofimmunohistochemicalstaining
AT jeffreyholzbeierlein nearmissdiagnosesofsolitarybladdertumorshighlighttheimportanceofimmunohistochemicalstaining
AT johnatayloriii nearmissdiagnosesofsolitarybladdertumorshighlighttheimportanceofimmunohistochemicalstaining