Inhibitory Effects of Far-Infrared Irradiation Generated by Ceramic Material on Murine Melanoma Cell Growth
The biological effects of specific wavelengths, so-called “far-infrared radiation” produced from ceramic material (cFIR), on whole organisms are not yet well understood. In this study, we investigated the biological effects of cFIR on murine melanoma cells (B16-F10) at body temperature. cFIR irradia...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | International Journal of Photoenergy |
| Online Access: | http://dx.doi.org/10.1155/2012/646845 |
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| author | Ting-Kai Leung Chin-Feng Chan Ping-Shan Lai Chih-Hui Yang Chia-Yen Hsu Yung-Sheng Lin |
| author_facet | Ting-Kai Leung Chin-Feng Chan Ping-Shan Lai Chih-Hui Yang Chia-Yen Hsu Yung-Sheng Lin |
| author_sort | Ting-Kai Leung |
| collection | DOAJ |
| description | The biological effects of specific wavelengths, so-called “far-infrared radiation” produced from ceramic material (cFIR), on whole organisms are not yet well understood. In this study, we investigated the biological effects of cFIR on murine melanoma cells (B16-F10) at body temperature. cFIR irradiation treatment for 48 h resulted in an 11.8% decrease in the proliferation of melanoma cells relative to the control. Meanwhile, incubation of cells with cFIR for 48 h significantly resulted in 56.9% and 15.7% decreases in the intracellular heat shock protein (HSP)70 and intracellular nitric oxide (iNO) contents, respectively. Furthermore, cFIR treatment induced 6.4% and 12.3% increases in intracellular reactive oxygen species stained by 5-(and 6)-carboxyl-2′,7′-dichlorodihydrofluorescein diacetate and dihydrorhodamine 123, respectively. Since malignant melanomas are known to have high HSP70 expression and iNO activity, the suppressive effects of cFIR on HSP70 and NO may warrant future interest in antitumor applications. |
| format | Article |
| id | doaj-art-5fed1921bdbb49718c6a738498cb0465 |
| institution | Kabale University |
| issn | 1110-662X 1687-529X |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Photoenergy |
| spelling | doaj-art-5fed1921bdbb49718c6a738498cb04652025-02-03T01:03:00ZengWileyInternational Journal of Photoenergy1110-662X1687-529X2012-01-01201210.1155/2012/646845646845Inhibitory Effects of Far-Infrared Irradiation Generated by Ceramic Material on Murine Melanoma Cell GrowthTing-Kai Leung0Chin-Feng Chan1Ping-Shan Lai2Chih-Hui Yang3Chia-Yen Hsu4Yung-Sheng Lin5Department of Radiology, School of Medicine, Taipei Medical University and Hospital, Taipei 110, TaiwanDepartment of Applied Cosmetology and Master Program of Cosmetic Science, Hungkuang University, Taichung 433, TaiwanDepartment of Chemistry, National Chung Hsing University, Taichung 402, TaiwanDepartment of Biological Science and Technology, I-Shou University, Kaohsiung 824, TaiwanDepartment of Chemistry, National Chung Hsing University, Taichung 402, TaiwanDepartment of Applied Cosmetology and Master Program of Cosmetic Science, Hungkuang University, Taichung 433, TaiwanThe biological effects of specific wavelengths, so-called “far-infrared radiation” produced from ceramic material (cFIR), on whole organisms are not yet well understood. In this study, we investigated the biological effects of cFIR on murine melanoma cells (B16-F10) at body temperature. cFIR irradiation treatment for 48 h resulted in an 11.8% decrease in the proliferation of melanoma cells relative to the control. Meanwhile, incubation of cells with cFIR for 48 h significantly resulted in 56.9% and 15.7% decreases in the intracellular heat shock protein (HSP)70 and intracellular nitric oxide (iNO) contents, respectively. Furthermore, cFIR treatment induced 6.4% and 12.3% increases in intracellular reactive oxygen species stained by 5-(and 6)-carboxyl-2′,7′-dichlorodihydrofluorescein diacetate and dihydrorhodamine 123, respectively. Since malignant melanomas are known to have high HSP70 expression and iNO activity, the suppressive effects of cFIR on HSP70 and NO may warrant future interest in antitumor applications.http://dx.doi.org/10.1155/2012/646845 |
| spellingShingle | Ting-Kai Leung Chin-Feng Chan Ping-Shan Lai Chih-Hui Yang Chia-Yen Hsu Yung-Sheng Lin Inhibitory Effects of Far-Infrared Irradiation Generated by Ceramic Material on Murine Melanoma Cell Growth International Journal of Photoenergy |
| title | Inhibitory Effects of Far-Infrared Irradiation Generated by Ceramic Material on Murine Melanoma Cell Growth |
| title_full | Inhibitory Effects of Far-Infrared Irradiation Generated by Ceramic Material on Murine Melanoma Cell Growth |
| title_fullStr | Inhibitory Effects of Far-Infrared Irradiation Generated by Ceramic Material on Murine Melanoma Cell Growth |
| title_full_unstemmed | Inhibitory Effects of Far-Infrared Irradiation Generated by Ceramic Material on Murine Melanoma Cell Growth |
| title_short | Inhibitory Effects of Far-Infrared Irradiation Generated by Ceramic Material on Murine Melanoma Cell Growth |
| title_sort | inhibitory effects of far infrared irradiation generated by ceramic material on murine melanoma cell growth |
| url | http://dx.doi.org/10.1155/2012/646845 |
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