Advances in research on gut microbiota and allergic diseases in children
Epidemiological studies indicate a rising prevalence of allergic diseases, now recognized as a major global public health concern. In children, the progression of these diseases often follows the ''atopic march,'' beginning with eczema, followed by food allergies, allergic rhinit...
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Elsevier
2025-01-01
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| Series: | Current Research in Microbial Sciences |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666517425000240 |
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| author | Heng Ke Hongbing Yao Ping Wei |
| author_facet | Heng Ke Hongbing Yao Ping Wei |
| author_sort | Heng Ke |
| collection | DOAJ |
| description | Epidemiological studies indicate a rising prevalence of allergic diseases, now recognized as a major global public health concern. In children, the progression of these diseases often follows the ''atopic march,'' beginning with eczema, followed by food allergies, allergic rhinitis, and asthma. Recent research has linked gut microbiota dysbiosis to the development of allergic diseases in children. The gut microbiota, a crucial component of human health, plays a vital role in maintaining overall well-being, highlighting its potential in preventing and modifying the course of allergic diseases. This review examines the relationship between childhood allergic diseases and gut microbiota, drawing on the latest evidence. We first elaborated the concepts of allergic diseases and gut microbiota, followed by a discussion of the developmental trajectory of the gut microbiota in healthy children. This review further explored the richness, diversity, and composition of the gut microbiota, as well as specific microbial taxa associated with allergic disease. Lastly, we discussed the current status and future potential of probiotic interventions in managing pediatric allergic diseases. |
| format | Article |
| id | doaj-art-5fe7af0dec044f97a894e35ae2cf8670 |
| institution | OA Journals |
| issn | 2666-5174 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Current Research in Microbial Sciences |
| spelling | doaj-art-5fe7af0dec044f97a894e35ae2cf86702025-08-20T02:35:45ZengElsevierCurrent Research in Microbial Sciences2666-51742025-01-01810036210.1016/j.crmicr.2025.100362Advances in research on gut microbiota and allergic diseases in childrenHeng Ke0Hongbing Yao1Ping Wei2Department of Otolaryngology, Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Pediatrics, Chongqing, ChinaCorresponding authors.; Department of Otolaryngology, Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Pediatrics, Chongqing, ChinaCorresponding authors.; Department of Otolaryngology, Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Pediatrics, Chongqing, ChinaEpidemiological studies indicate a rising prevalence of allergic diseases, now recognized as a major global public health concern. In children, the progression of these diseases often follows the ''atopic march,'' beginning with eczema, followed by food allergies, allergic rhinitis, and asthma. Recent research has linked gut microbiota dysbiosis to the development of allergic diseases in children. The gut microbiota, a crucial component of human health, plays a vital role in maintaining overall well-being, highlighting its potential in preventing and modifying the course of allergic diseases. This review examines the relationship between childhood allergic diseases and gut microbiota, drawing on the latest evidence. We first elaborated the concepts of allergic diseases and gut microbiota, followed by a discussion of the developmental trajectory of the gut microbiota in healthy children. This review further explored the richness, diversity, and composition of the gut microbiota, as well as specific microbial taxa associated with allergic disease. Lastly, we discussed the current status and future potential of probiotic interventions in managing pediatric allergic diseases.http://www.sciencedirect.com/science/article/pii/S2666517425000240Atopic dermatitisFood allergyAllergic rhinitisAsthmaGut microbiotaProbiotics |
| spellingShingle | Heng Ke Hongbing Yao Ping Wei Advances in research on gut microbiota and allergic diseases in children Current Research in Microbial Sciences Atopic dermatitis Food allergy Allergic rhinitis Asthma Gut microbiota Probiotics |
| title | Advances in research on gut microbiota and allergic diseases in children |
| title_full | Advances in research on gut microbiota and allergic diseases in children |
| title_fullStr | Advances in research on gut microbiota and allergic diseases in children |
| title_full_unstemmed | Advances in research on gut microbiota and allergic diseases in children |
| title_short | Advances in research on gut microbiota and allergic diseases in children |
| title_sort | advances in research on gut microbiota and allergic diseases in children |
| topic | Atopic dermatitis Food allergy Allergic rhinitis Asthma Gut microbiota Probiotics |
| url | http://www.sciencedirect.com/science/article/pii/S2666517425000240 |
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