Survival and Mortality in Hospitalized Children with COVID-19: A Referral Center Experience in Yazd, Iran

Introduction. COVID-19 prognostic risk factors, therapeutic protocols, and clinical outcomes in pediatric cases are still under investigation. Materials and Methods. This historical cohort study evaluated the survival time of hospitalized children (1 month–18 years old) with COVID-19 admitted from M...

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Main Authors: Farimah Shamsi, Mehran Karimi, Zahra Nafei, Elahe Akbarian
Format: Article
Language:English
Published: Wiley 2023-01-01
Series:Canadian Journal of Infectious Diseases and Medical Microbiology
Online Access:http://dx.doi.org/10.1155/2023/5205188
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author Farimah Shamsi
Mehran Karimi
Zahra Nafei
Elahe Akbarian
author_facet Farimah Shamsi
Mehran Karimi
Zahra Nafei
Elahe Akbarian
author_sort Farimah Shamsi
collection DOAJ
description Introduction. COVID-19 prognostic risk factors, therapeutic protocols, and clinical outcomes in pediatric cases are still under investigation. Materials and Methods. This historical cohort study evaluated the survival time of hospitalized children (1 month–18 years old) with COVID-19 admitted from March 2020 to August 2021 to an educational hospital in Yazd, Iran. The follow-up of patients was performed at least one month after discharge. Results. From 183 hospitalized cases, 24 children were deceased. The median age of patients was 5.41, and 54.2% were male. The survival rate after one-month follow-up was 0.88, and the most significant predictors associated with survival time were the male sex, positive history of hospitalization, lymphopenia, hypoxia, and length of stay more than two weeks using Bayesian Cox regression analysis. Conclusion. Accurate estimation of the impact of predictors on poor outcomes may help healthcare providers use therapeutic protocols based on risk factors and healthcare requirements of each patient to improve their survival.
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institution Kabale University
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spelling doaj-art-5fe15ecacff742bfa6aa2ec84ab522712025-02-03T05:52:24ZengWileyCanadian Journal of Infectious Diseases and Medical Microbiology1918-14932023-01-01202310.1155/2023/5205188Survival and Mortality in Hospitalized Children with COVID-19: A Referral Center Experience in Yazd, IranFarimah Shamsi0Mehran Karimi1Zahra Nafei2Elahe Akbarian3Center for Healthcare Data ModelingChildren Growth Disorder Research CenterChildren Growth Disorder Research CenterChildren Growth Disorder Research CenterIntroduction. COVID-19 prognostic risk factors, therapeutic protocols, and clinical outcomes in pediatric cases are still under investigation. Materials and Methods. This historical cohort study evaluated the survival time of hospitalized children (1 month–18 years old) with COVID-19 admitted from March 2020 to August 2021 to an educational hospital in Yazd, Iran. The follow-up of patients was performed at least one month after discharge. Results. From 183 hospitalized cases, 24 children were deceased. The median age of patients was 5.41, and 54.2% were male. The survival rate after one-month follow-up was 0.88, and the most significant predictors associated with survival time were the male sex, positive history of hospitalization, lymphopenia, hypoxia, and length of stay more than two weeks using Bayesian Cox regression analysis. Conclusion. Accurate estimation of the impact of predictors on poor outcomes may help healthcare providers use therapeutic protocols based on risk factors and healthcare requirements of each patient to improve their survival.http://dx.doi.org/10.1155/2023/5205188
spellingShingle Farimah Shamsi
Mehran Karimi
Zahra Nafei
Elahe Akbarian
Survival and Mortality in Hospitalized Children with COVID-19: A Referral Center Experience in Yazd, Iran
Canadian Journal of Infectious Diseases and Medical Microbiology
title Survival and Mortality in Hospitalized Children with COVID-19: A Referral Center Experience in Yazd, Iran
title_full Survival and Mortality in Hospitalized Children with COVID-19: A Referral Center Experience in Yazd, Iran
title_fullStr Survival and Mortality in Hospitalized Children with COVID-19: A Referral Center Experience in Yazd, Iran
title_full_unstemmed Survival and Mortality in Hospitalized Children with COVID-19: A Referral Center Experience in Yazd, Iran
title_short Survival and Mortality in Hospitalized Children with COVID-19: A Referral Center Experience in Yazd, Iran
title_sort survival and mortality in hospitalized children with covid 19 a referral center experience in yazd iran
url http://dx.doi.org/10.1155/2023/5205188
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AT zahranafei survivalandmortalityinhospitalizedchildrenwithcovid19areferralcenterexperienceinyazdiran
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