The impact of perceived caregiver anxiety and stress during childhood on late-life depression: evidence from the China Health and Retirement Longitudinal Study

IntroductionThis study investigates the long-term impact of perceived caregiver anxiety and stress during childhood on late-life depression. Adverse childhood experiences related to caregiver mental health may significantly influence emotional well-being, and this study utilizes data from the China...

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Main Authors: Liuyin Jin, Dongdong Wang, Dengxian Yang, Qiong Jin, Mengye Cao, Yuanyuan Li, Jiajie Yang, Guoming Xie, Wenwu Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Psychiatry
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Online Access:https://www.frontiersin.org/articles/10.3389/fpsyt.2025.1507566/full
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author Liuyin Jin
Liuyin Jin
Dongdong Wang
Dengxian Yang
Qiong Jin
Mengye Cao
Yuanyuan Li
Jiajie Yang
Guoming Xie
Wenwu Zhang
author_facet Liuyin Jin
Liuyin Jin
Dongdong Wang
Dengxian Yang
Qiong Jin
Mengye Cao
Yuanyuan Li
Jiajie Yang
Guoming Xie
Wenwu Zhang
author_sort Liuyin Jin
collection DOAJ
description IntroductionThis study investigates the long-term impact of perceived caregiver anxiety and stress during childhood on late-life depression. Adverse childhood experiences related to caregiver mental health may significantly influence emotional well-being, and this study utilizes data from the China Health and Retirement Longitudinal Study (CHARLS) to explore these associations.MethodsCHARLS data were analyzed for individuals who reported perceived caregiver anxiety and stress. Depression was measured using the CES-10 depression scale. Multivariate logistic regression models examined the relationship between caregiver anxiety and stress frequency and late-life depression, adjusting for confounders like socioeconomic status, health behaviors, and demographics.ResultsChildhood exposure to caregiver anxiety and stress significantly increased the risk of depression in later life (p < 0.05), with stronger effects observed among individuals with female caregivers. The risk escalated with the frequency of caregiver anxiety episodes. After adjusting for covariates, the association for male caregivers weakened, highlighting the potential role of other mediators.DiscussionThe results highlight the critical importance of parental mental health, especially maternal anxiety, in mitigating intergenerational mental health risks. Targeted interventions for caregiver mental health, particularly for female caregivers, are crucial. Longitudinal studies are needed to better establish causality and further investigate these mechanisms.
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spelling doaj-art-5fd8193191434595b97cd4463090f80c2025-01-31T06:40:53ZengFrontiers Media S.A.Frontiers in Psychiatry1664-06402025-01-011610.3389/fpsyt.2025.15075661507566The impact of perceived caregiver anxiety and stress during childhood on late-life depression: evidence from the China Health and Retirement Longitudinal StudyLiuyin Jin0Liuyin Jin1Dongdong Wang2Dengxian Yang3Qiong Jin4Mengye Cao5Yuanyuan Li6Jiajie Yang7Guoming Xie8Wenwu Zhang9Ningbo University Affiliated Kangning Hospital Child and Adolescent Psychiatry Center, Ningbo, Zhejiang, ChinaScience and Education Department, Lishui Second People's Hospital, Lishui, ChinaNeurology Department, Peking University Zibo Hospital, Zibo, Shandong, ChinaChild and Adolescent Psychiatry Center, Ningbo University Affiliated Kangning Hospital, Ningbo, Zhejiang, ChinaChild and Adolescent Psychiatry Center, Ningbo University Affiliated Kangning Hospital, Ningbo, Zhejiang, ChinaChild and Adolescent Psychiatry Center, Ningbo University Affiliated Kangning Hospital, Ningbo, Zhejiang, ChinaChild and Adolescent Psychiatry Center, Ningbo University Affiliated Kangning Hospital, Ningbo, Zhejiang, ChinaChild and Adolescent Psychiatry Center, Ningbo University Affiliated Kangning Hospital, Ningbo, Zhejiang, ChinaDepartment of Neurology, The Affiliated Lihuili Hospital of Ningbo University, Ningbo University, Ningbo, ChinaChild and Adolescent Psychiatry Center, Ningbo University Affiliated Kangning Hospital, Ningbo, Zhejiang, ChinaIntroductionThis study investigates the long-term impact of perceived caregiver anxiety and stress during childhood on late-life depression. Adverse childhood experiences related to caregiver mental health may significantly influence emotional well-being, and this study utilizes data from the China Health and Retirement Longitudinal Study (CHARLS) to explore these associations.MethodsCHARLS data were analyzed for individuals who reported perceived caregiver anxiety and stress. Depression was measured using the CES-10 depression scale. Multivariate logistic regression models examined the relationship between caregiver anxiety and stress frequency and late-life depression, adjusting for confounders like socioeconomic status, health behaviors, and demographics.ResultsChildhood exposure to caregiver anxiety and stress significantly increased the risk of depression in later life (p < 0.05), with stronger effects observed among individuals with female caregivers. The risk escalated with the frequency of caregiver anxiety episodes. After adjusting for covariates, the association for male caregivers weakened, highlighting the potential role of other mediators.DiscussionThe results highlight the critical importance of parental mental health, especially maternal anxiety, in mitigating intergenerational mental health risks. Targeted interventions for caregiver mental health, particularly for female caregivers, are crucial. Longitudinal studies are needed to better establish causality and further investigate these mechanisms.https://www.frontiersin.org/articles/10.3389/fpsyt.2025.1507566/fullchildhood adversityperceived caregiver anxietyperceived caregiver stresslate-life depressionintergenerational mental healthCHARLS
spellingShingle Liuyin Jin
Liuyin Jin
Dongdong Wang
Dengxian Yang
Qiong Jin
Mengye Cao
Yuanyuan Li
Jiajie Yang
Guoming Xie
Wenwu Zhang
The impact of perceived caregiver anxiety and stress during childhood on late-life depression: evidence from the China Health and Retirement Longitudinal Study
Frontiers in Psychiatry
childhood adversity
perceived caregiver anxiety
perceived caregiver stress
late-life depression
intergenerational mental health
CHARLS
title The impact of perceived caregiver anxiety and stress during childhood on late-life depression: evidence from the China Health and Retirement Longitudinal Study
title_full The impact of perceived caregiver anxiety and stress during childhood on late-life depression: evidence from the China Health and Retirement Longitudinal Study
title_fullStr The impact of perceived caregiver anxiety and stress during childhood on late-life depression: evidence from the China Health and Retirement Longitudinal Study
title_full_unstemmed The impact of perceived caregiver anxiety and stress during childhood on late-life depression: evidence from the China Health and Retirement Longitudinal Study
title_short The impact of perceived caregiver anxiety and stress during childhood on late-life depression: evidence from the China Health and Retirement Longitudinal Study
title_sort impact of perceived caregiver anxiety and stress during childhood on late life depression evidence from the china health and retirement longitudinal study
topic childhood adversity
perceived caregiver anxiety
perceived caregiver stress
late-life depression
intergenerational mental health
CHARLS
url https://www.frontiersin.org/articles/10.3389/fpsyt.2025.1507566/full
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