Research on the mechanism of Astragaloside Ⅳ in regulating urotensin Ⅱ-induced renal tubular epithelial cells injury through the RhoA/ROCK1 signaling pathway

ObjectiveTo explore the mechanism by which astragaloside IV (AS-IV) regulates the injury of normal rat kidney cells-52E (NRK-52E) induced by Urotensin II (UII) through the Ras homolog gene family member A (RhoA)/Rho-associated protein kinase 1 (ROCK1) signaling pathway.MethodsNRK-52E cells were cult...

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Bibliographic Details
Main Authors: Liu Qian-wei, Liu Wen-yuan, Fang Jing-ai
Format: Article
Language:zho
Published: Editorial Department of Journal of Clinical Nephrology 2025-03-01
Series:Linchuang shenzangbing zazhi
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Online Access:http://www.lcszb.com/article/doi/10.3969/j.issn.1671-2390.2025.03.008
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