A Biologically Inspired and Protein-Based Bio-Cyber Interface for the Internet of Bio-Nano Things
The Internet of Things (IoT) has changed the way how we interact with our physical environment, enabling connectivity and communication between physical and virtual entities, e.g., for digital twin applications. However, as we step beyond the IoT, developing the Internet of Bio-Nano Things (IoBNT),...
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Elsevier
2025-03-01
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Series: | Biosensors and Bioelectronics: X |
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Online Access: | http://www.sciencedirect.com/science/article/pii/S2590137024001365 |
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author | Pit Hofmann Juan A. Cabrera Gunnar Schulte Frank H.P. Fitzek |
author_facet | Pit Hofmann Juan A. Cabrera Gunnar Schulte Frank H.P. Fitzek |
author_sort | Pit Hofmann |
collection | DOAJ |
description | The Internet of Things (IoT) has changed the way how we interact with our physical environment, enabling connectivity and communication between physical and virtual entities, e.g., for digital twin applications. However, as we step beyond the IoT, developing the Internet of Bio-Nano Things (IoBNT), where biological and nanoscale entities will be included in our communication networks, includes challenges as well as opportunities. In the IoBNT, the role of Bio-Cyber Interfaces (BCIs) is still underscored, representing necessary building blocks that ensure the bidirectional information exchange between biological and digital communication systems. The application area of the IoBNT spans diverse domains, e.g., healthcare, personalized medicine, or environmental monitoring. This work proposes a theoretical framework for a BCI, leveraging advances in biotechnology, nanotechnology, and communication engineering to establish an interface for exchanging information between biological entities, nanoscale devices, and the digital world. Therefore, we discuss the key components of the proposed BCI framework. Furthermore, we survey the existing literature of biologically inspired BCIs and outline potential use cases and benefits of integrating BCIs in the IoBNT for various domains, such as healthcare and environmental monitoring. |
format | Article |
id | doaj-art-5f99fc111a984064a7e5d18046bde80d |
institution | Kabale University |
issn | 2590-1370 |
language | English |
publishDate | 2025-03-01 |
publisher | Elsevier |
record_format | Article |
series | Biosensors and Bioelectronics: X |
spelling | doaj-art-5f99fc111a984064a7e5d18046bde80d2025-01-22T05:43:55ZengElsevierBiosensors and Bioelectronics: X2590-13702025-03-0122100572A Biologically Inspired and Protein-Based Bio-Cyber Interface for the Internet of Bio-Nano ThingsPit Hofmann0Juan A. Cabrera1Gunnar Schulte2Frank H.P. Fitzek3Deutsche Telekom Chair of Communication Networks, Technische Universität Dresden, GermanyDeutsche Telekom Chair of Communication Networks, Technische Universität Dresden, GermanySection of Receptor Biology & Signaling, Department of Physiology and Pharmacology, Karolinska Institute, Stockholm, Sweden; Corresponding authors.Deutsche Telekom Chair of Communication Networks, Technische Universität Dresden, Germany; Centre for Tactile Internet with Human-in-the-Loop (CeTI), Dresden, Germany; Corresponding authors.The Internet of Things (IoT) has changed the way how we interact with our physical environment, enabling connectivity and communication between physical and virtual entities, e.g., for digital twin applications. However, as we step beyond the IoT, developing the Internet of Bio-Nano Things (IoBNT), where biological and nanoscale entities will be included in our communication networks, includes challenges as well as opportunities. In the IoBNT, the role of Bio-Cyber Interfaces (BCIs) is still underscored, representing necessary building blocks that ensure the bidirectional information exchange between biological and digital communication systems. The application area of the IoBNT spans diverse domains, e.g., healthcare, personalized medicine, or environmental monitoring. This work proposes a theoretical framework for a BCI, leveraging advances in biotechnology, nanotechnology, and communication engineering to establish an interface for exchanging information between biological entities, nanoscale devices, and the digital world. Therefore, we discuss the key components of the proposed BCI framework. Furthermore, we survey the existing literature of biologically inspired BCIs and outline potential use cases and benefits of integrating BCIs in the IoBNT for various domains, such as healthcare and environmental monitoring.http://www.sciencedirect.com/science/article/pii/S2590137024001365Bio-Cyber InterfaceMolecular CommunicationInternet of Bio-Nano ThingsG Protein-Coupled ReceptorGPCRGenetically Encoded Biosensor |
spellingShingle | Pit Hofmann Juan A. Cabrera Gunnar Schulte Frank H.P. Fitzek A Biologically Inspired and Protein-Based Bio-Cyber Interface for the Internet of Bio-Nano Things Biosensors and Bioelectronics: X Bio-Cyber Interface Molecular Communication Internet of Bio-Nano Things G Protein-Coupled Receptor GPCR Genetically Encoded Biosensor |
title | A Biologically Inspired and Protein-Based Bio-Cyber Interface for the Internet of Bio-Nano Things |
title_full | A Biologically Inspired and Protein-Based Bio-Cyber Interface for the Internet of Bio-Nano Things |
title_fullStr | A Biologically Inspired and Protein-Based Bio-Cyber Interface for the Internet of Bio-Nano Things |
title_full_unstemmed | A Biologically Inspired and Protein-Based Bio-Cyber Interface for the Internet of Bio-Nano Things |
title_short | A Biologically Inspired and Protein-Based Bio-Cyber Interface for the Internet of Bio-Nano Things |
title_sort | biologically inspired and protein based bio cyber interface for the internet of bio nano things |
topic | Bio-Cyber Interface Molecular Communication Internet of Bio-Nano Things G Protein-Coupled Receptor GPCR Genetically Encoded Biosensor |
url | http://www.sciencedirect.com/science/article/pii/S2590137024001365 |
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