A Biologically Inspired and Protein-Based Bio-Cyber Interface for the Internet of Bio-Nano Things

The Internet of Things (IoT) has changed the way how we interact with our physical environment, enabling connectivity and communication between physical and virtual entities, e.g., for digital twin applications. However, as we step beyond the IoT, developing the Internet of Bio-Nano Things (IoBNT),...

Full description

Saved in:
Bibliographic Details
Main Authors: Pit Hofmann, Juan A. Cabrera, Gunnar Schulte, Frank H.P. Fitzek
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Biosensors and Bioelectronics: X
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2590137024001365
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832591770367557632
author Pit Hofmann
Juan A. Cabrera
Gunnar Schulte
Frank H.P. Fitzek
author_facet Pit Hofmann
Juan A. Cabrera
Gunnar Schulte
Frank H.P. Fitzek
author_sort Pit Hofmann
collection DOAJ
description The Internet of Things (IoT) has changed the way how we interact with our physical environment, enabling connectivity and communication between physical and virtual entities, e.g., for digital twin applications. However, as we step beyond the IoT, developing the Internet of Bio-Nano Things (IoBNT), where biological and nanoscale entities will be included in our communication networks, includes challenges as well as opportunities. In the IoBNT, the role of Bio-Cyber Interfaces (BCIs) is still underscored, representing necessary building blocks that ensure the bidirectional information exchange between biological and digital communication systems. The application area of the IoBNT spans diverse domains, e.g., healthcare, personalized medicine, or environmental monitoring. This work proposes a theoretical framework for a BCI, leveraging advances in biotechnology, nanotechnology, and communication engineering to establish an interface for exchanging information between biological entities, nanoscale devices, and the digital world. Therefore, we discuss the key components of the proposed BCI framework. Furthermore, we survey the existing literature of biologically inspired BCIs and outline potential use cases and benefits of integrating BCIs in the IoBNT for various domains, such as healthcare and environmental monitoring.
format Article
id doaj-art-5f99fc111a984064a7e5d18046bde80d
institution Kabale University
issn 2590-1370
language English
publishDate 2025-03-01
publisher Elsevier
record_format Article
series Biosensors and Bioelectronics: X
spelling doaj-art-5f99fc111a984064a7e5d18046bde80d2025-01-22T05:43:55ZengElsevierBiosensors and Bioelectronics: X2590-13702025-03-0122100572A Biologically Inspired and Protein-Based Bio-Cyber Interface for the Internet of Bio-Nano ThingsPit Hofmann0Juan A. Cabrera1Gunnar Schulte2Frank H.P. Fitzek3Deutsche Telekom Chair of Communication Networks, Technische Universität Dresden, GermanyDeutsche Telekom Chair of Communication Networks, Technische Universität Dresden, GermanySection of Receptor Biology & Signaling, Department of Physiology and Pharmacology, Karolinska Institute, Stockholm, Sweden; Corresponding authors.Deutsche Telekom Chair of Communication Networks, Technische Universität Dresden, Germany; Centre for Tactile Internet with Human-in-the-Loop (CeTI), Dresden, Germany; Corresponding authors.The Internet of Things (IoT) has changed the way how we interact with our physical environment, enabling connectivity and communication between physical and virtual entities, e.g., for digital twin applications. However, as we step beyond the IoT, developing the Internet of Bio-Nano Things (IoBNT), where biological and nanoscale entities will be included in our communication networks, includes challenges as well as opportunities. In the IoBNT, the role of Bio-Cyber Interfaces (BCIs) is still underscored, representing necessary building blocks that ensure the bidirectional information exchange between biological and digital communication systems. The application area of the IoBNT spans diverse domains, e.g., healthcare, personalized medicine, or environmental monitoring. This work proposes a theoretical framework for a BCI, leveraging advances in biotechnology, nanotechnology, and communication engineering to establish an interface for exchanging information between biological entities, nanoscale devices, and the digital world. Therefore, we discuss the key components of the proposed BCI framework. Furthermore, we survey the existing literature of biologically inspired BCIs and outline potential use cases and benefits of integrating BCIs in the IoBNT for various domains, such as healthcare and environmental monitoring.http://www.sciencedirect.com/science/article/pii/S2590137024001365Bio-Cyber InterfaceMolecular CommunicationInternet of Bio-Nano ThingsG Protein-Coupled ReceptorGPCRGenetically Encoded Biosensor
spellingShingle Pit Hofmann
Juan A. Cabrera
Gunnar Schulte
Frank H.P. Fitzek
A Biologically Inspired and Protein-Based Bio-Cyber Interface for the Internet of Bio-Nano Things
Biosensors and Bioelectronics: X
Bio-Cyber Interface
Molecular Communication
Internet of Bio-Nano Things
G Protein-Coupled Receptor
GPCR
Genetically Encoded Biosensor
title A Biologically Inspired and Protein-Based Bio-Cyber Interface for the Internet of Bio-Nano Things
title_full A Biologically Inspired and Protein-Based Bio-Cyber Interface for the Internet of Bio-Nano Things
title_fullStr A Biologically Inspired and Protein-Based Bio-Cyber Interface for the Internet of Bio-Nano Things
title_full_unstemmed A Biologically Inspired and Protein-Based Bio-Cyber Interface for the Internet of Bio-Nano Things
title_short A Biologically Inspired and Protein-Based Bio-Cyber Interface for the Internet of Bio-Nano Things
title_sort biologically inspired and protein based bio cyber interface for the internet of bio nano things
topic Bio-Cyber Interface
Molecular Communication
Internet of Bio-Nano Things
G Protein-Coupled Receptor
GPCR
Genetically Encoded Biosensor
url http://www.sciencedirect.com/science/article/pii/S2590137024001365
work_keys_str_mv AT pithofmann abiologicallyinspiredandproteinbasedbiocyberinterfacefortheinternetofbionanothings
AT juanacabrera abiologicallyinspiredandproteinbasedbiocyberinterfacefortheinternetofbionanothings
AT gunnarschulte abiologicallyinspiredandproteinbasedbiocyberinterfacefortheinternetofbionanothings
AT frankhpfitzek abiologicallyinspiredandproteinbasedbiocyberinterfacefortheinternetofbionanothings
AT pithofmann biologicallyinspiredandproteinbasedbiocyberinterfacefortheinternetofbionanothings
AT juanacabrera biologicallyinspiredandproteinbasedbiocyberinterfacefortheinternetofbionanothings
AT gunnarschulte biologicallyinspiredandproteinbasedbiocyberinterfacefortheinternetofbionanothings
AT frankhpfitzek biologicallyinspiredandproteinbasedbiocyberinterfacefortheinternetofbionanothings