Systematic review and meta-analysis of the effect of zinc on wound healing
In times of metabolic stress, the demand for nutrients increases, which is essential to prevent delayed healing and development of chronic wounds. This study presents a systematic review and meta-analysis examining the effect of zinc treatment on wound healing. The review followed Preferred Reportin...
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| Format: | Article |
| Language: | English |
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BMJ Publishing Group
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| Series: | BMJ Nutrition, Prevention & Health |
| Online Access: | https://nutrition.bmj.com/content/early/2025/02/03/bmjnph-2024-000952.full |
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| _version_ | 1832540668254224384 |
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| author | Nazanin Zand Elena Arribas Lopez Omorogieva Ojo Tony Kochhar |
| author_facet | Nazanin Zand Elena Arribas Lopez Omorogieva Ojo Tony Kochhar |
| author_sort | Nazanin Zand |
| collection | DOAJ |
| description | In times of metabolic stress, the demand for nutrients increases, which is essential to prevent delayed healing and development of chronic wounds. This study presents a systematic review and meta-analysis examining the effect of zinc treatment on wound healing. The review followed Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines and included data from four electronic data bases. Five clinical trials met the inclusion criteria. The meta-analysis suggested that zinc treatment may be associated with improvements in ulcers healing at the final endpoint MD: 1.41 (95% CI 1.04, 1.92, p = 0.03). Given the limitations of the included studies, a Grading of Recommendations, Assessment, Development and Evaluation assessment indicated a moderate quality of evidence. |
| format | Article |
| id | doaj-art-5f7276ef5789464e93c54e3472e84f4c |
| institution | Kabale University |
| issn | 2516-5542 |
| language | English |
| publisher | BMJ Publishing Group |
| record_format | Article |
| series | BMJ Nutrition, Prevention & Health |
| spelling | doaj-art-5f7276ef5789464e93c54e3472e84f4c2025-02-04T16:55:09ZengBMJ Publishing GroupBMJ Nutrition, Prevention & Health2516-554210.1136/bmjnph-2024-000952Systematic review and meta-analysis of the effect of zinc on wound healingNazanin Zand0Elena Arribas Lopez1Omorogieva Ojo2Tony Kochhar3Food and Markets Department, University of Greenwich Faculty of Engineering and Science, Chatham, UKFood and Markets Department, University of Greenwich Faculty of Engineering and Science, Chatham, UKSchool of Health Sciences, University of Greenwich Faculty of Education Health and Human Sciences, London, UKHCA London Bridge Hospital, London, UKIn times of metabolic stress, the demand for nutrients increases, which is essential to prevent delayed healing and development of chronic wounds. This study presents a systematic review and meta-analysis examining the effect of zinc treatment on wound healing. The review followed Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines and included data from four electronic data bases. Five clinical trials met the inclusion criteria. The meta-analysis suggested that zinc treatment may be associated with improvements in ulcers healing at the final endpoint MD: 1.41 (95% CI 1.04, 1.92, p = 0.03). Given the limitations of the included studies, a Grading of Recommendations, Assessment, Development and Evaluation assessment indicated a moderate quality of evidence.https://nutrition.bmj.com/content/early/2025/02/03/bmjnph-2024-000952.full |
| spellingShingle | Nazanin Zand Elena Arribas Lopez Omorogieva Ojo Tony Kochhar Systematic review and meta-analysis of the effect of zinc on wound healing BMJ Nutrition, Prevention & Health |
| title | Systematic review and meta-analysis of the effect of zinc on wound healing |
| title_full | Systematic review and meta-analysis of the effect of zinc on wound healing |
| title_fullStr | Systematic review and meta-analysis of the effect of zinc on wound healing |
| title_full_unstemmed | Systematic review and meta-analysis of the effect of zinc on wound healing |
| title_short | Systematic review and meta-analysis of the effect of zinc on wound healing |
| title_sort | systematic review and meta analysis of the effect of zinc on wound healing |
| url | https://nutrition.bmj.com/content/early/2025/02/03/bmjnph-2024-000952.full |
| work_keys_str_mv | AT nazaninzand systematicreviewandmetaanalysisoftheeffectofzinconwoundhealing AT elenaarribaslopez systematicreviewandmetaanalysisoftheeffectofzinconwoundhealing AT omorogievaojo systematicreviewandmetaanalysisoftheeffectofzinconwoundhealing AT tonykochhar systematicreviewandmetaanalysisoftheeffectofzinconwoundhealing |