Genomic characterization of tumor mutational burden-high breast carcinomas

Genomic characterization of tumor mutational burden-high breast carcinomas

Abstract Tumor mutational burden (TMB) has emerged as a potential surrogate for neoantigen load and an indicator of immune checkpoint (IC)-blockade response; however, its precise significance in breast cancer (BC) is not fully understood. Here, we comprehensively characterized the genomic repertoire...

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Bibliographic Details
Main Authors: Theodore Vougiouklakis, Chad Vanderbilt, Satshil Rana, Abhinita Mohanty, Fresia Pareja, Edi Brogi, Christopher Schwartz, Maria E. Arcila, Marc Ladanyi, Hanna Y. Wen, Dara S. Ross
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:npj Precision Oncology
Online Access:https://doi.org/10.1038/s41698-025-01045-x
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