Obtaining and Characterizing Alginate/k-Carrageenan Hydrogel Cross-Linked with Adipic Dihydrazide
The aim of this paper is obtaining and characterizing hydrogels based on different ratios of oxidized alginate (oA) and k-carrageenan (C), chemically cross-linked with adipic dihydrazide (adh). The alginate (A) was first oxidized with sodium metaperiodate in order to transform it into the dialdehyde...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | Advances in Materials Science and Engineering |
| Online Access: | http://dx.doi.org/10.1155/2013/380716 |
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| author | Violeta Paşcalău Violeta Popescu George L. Popescu Mircea C. Dudescu Gheorghe Borodi Adrian M. Dinescu Marioara Moldovan |
| author_facet | Violeta Paşcalău Violeta Popescu George L. Popescu Mircea C. Dudescu Gheorghe Borodi Adrian M. Dinescu Marioara Moldovan |
| author_sort | Violeta Paşcalău |
| collection | DOAJ |
| description | The aim of this paper is obtaining and characterizing hydrogels based on different ratios of oxidized alginate (oA) and k-carrageenan (C), chemically cross-linked with adipic dihydrazide (adh). The alginate (A) was first oxidized with sodium metaperiodate in order to transform it into the dialdehyde derivative, a more reactive compound than alginate. A known procedure for oxidation of alginate with sodium metaperiodate in ethanol-water in order to improve alginate reactivity by transforming the hydroxyl end-groups into dialdehyde was used, preceded by a partially cleavage of the alginate chains. In the second stage, the mixture of dialdehydic derivative of oxidized alginate, k-carrageenan and glycerol subjected to reaction with adipic dihydrazide leads to a Semi-Interpenetrated Network covalently cross-linked alginate/k-carrageenan hydrogel (oACadh), based on the dihydrazone compound which is responsible for the chemical cross-linking. Pure alginate, k-carrageenan, oxidized alginate, adipic dihydrazide and the cross-linked hydrogel were characterized by: FTIR, XRD, and SEM. |
| format | Article |
| id | doaj-art-5f59db6ecde1485b88094d30aabe4201 |
| institution | Kabale University |
| issn | 1687-8434 1687-8442 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Advances in Materials Science and Engineering |
| spelling | doaj-art-5f59db6ecde1485b88094d30aabe42012025-02-03T06:06:05ZengWileyAdvances in Materials Science and Engineering1687-84341687-84422013-01-01201310.1155/2013/380716380716Obtaining and Characterizing Alginate/k-Carrageenan Hydrogel Cross-Linked with Adipic DihydrazideVioleta Paşcalău0Violeta Popescu1George L. Popescu2Mircea C. Dudescu3Gheorghe Borodi4Adrian M. Dinescu5Marioara Moldovan6Technical University of Cluj-Napoca, Muncii Avenue 103-105, 400641 Cluj-Napoca, RomaniaTechnical University of Cluj-Napoca, Muncii Avenue 103-105, 400641 Cluj-Napoca, RomaniaTechnical University of Cluj-Napoca, Muncii Avenue 103-105, 400641 Cluj-Napoca, RomaniaTechnical University of Cluj-Napoca, Muncii Avenue 103-105, 400641 Cluj-Napoca, RomaniaNational Institute for Research and Development of Isotopic and Molecular Technologies, Donath Street 65-103, 400293 Cluj-Napoca, RomaniaNational Institute for Research and Development in Microtechnologies, Erou Iancu Nicolae Street 126 A, 077190 Bucharest, RomaniaBabeş-Bolyai University, “Raluca Ripan” Institute for Research in Chemistry, Fântânele Street 30, 400294 Cluj-Napoca, RomaniaThe aim of this paper is obtaining and characterizing hydrogels based on different ratios of oxidized alginate (oA) and k-carrageenan (C), chemically cross-linked with adipic dihydrazide (adh). The alginate (A) was first oxidized with sodium metaperiodate in order to transform it into the dialdehyde derivative, a more reactive compound than alginate. A known procedure for oxidation of alginate with sodium metaperiodate in ethanol-water in order to improve alginate reactivity by transforming the hydroxyl end-groups into dialdehyde was used, preceded by a partially cleavage of the alginate chains. In the second stage, the mixture of dialdehydic derivative of oxidized alginate, k-carrageenan and glycerol subjected to reaction with adipic dihydrazide leads to a Semi-Interpenetrated Network covalently cross-linked alginate/k-carrageenan hydrogel (oACadh), based on the dihydrazone compound which is responsible for the chemical cross-linking. Pure alginate, k-carrageenan, oxidized alginate, adipic dihydrazide and the cross-linked hydrogel were characterized by: FTIR, XRD, and SEM.http://dx.doi.org/10.1155/2013/380716 |
| spellingShingle | Violeta Paşcalău Violeta Popescu George L. Popescu Mircea C. Dudescu Gheorghe Borodi Adrian M. Dinescu Marioara Moldovan Obtaining and Characterizing Alginate/k-Carrageenan Hydrogel Cross-Linked with Adipic Dihydrazide Advances in Materials Science and Engineering |
| title | Obtaining and Characterizing Alginate/k-Carrageenan Hydrogel Cross-Linked with Adipic Dihydrazide |
| title_full | Obtaining and Characterizing Alginate/k-Carrageenan Hydrogel Cross-Linked with Adipic Dihydrazide |
| title_fullStr | Obtaining and Characterizing Alginate/k-Carrageenan Hydrogel Cross-Linked with Adipic Dihydrazide |
| title_full_unstemmed | Obtaining and Characterizing Alginate/k-Carrageenan Hydrogel Cross-Linked with Adipic Dihydrazide |
| title_short | Obtaining and Characterizing Alginate/k-Carrageenan Hydrogel Cross-Linked with Adipic Dihydrazide |
| title_sort | obtaining and characterizing alginate k carrageenan hydrogel cross linked with adipic dihydrazide |
| url | http://dx.doi.org/10.1155/2013/380716 |
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