Celiac Disease in Patients with Cystic Fibrosis-Related Bone Disease

Both cystic fibrosis (CF) and celiac disease can cause low bone mineral density (BMD) and fractures. Celiac disease may occur at a higher frequency in patients with CF than the general population, and symptoms of these conditions may overlap. We report on two patients presenting with CF-related bone...

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Main Authors: Melissa S. Putman, Alexandra Haagensen, Isabel Neuringer, Leonard Sicilian
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:Case Reports in Endocrinology
Online Access:http://dx.doi.org/10.1155/2017/2652403
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author Melissa S. Putman
Alexandra Haagensen
Isabel Neuringer
Leonard Sicilian
author_facet Melissa S. Putman
Alexandra Haagensen
Isabel Neuringer
Leonard Sicilian
author_sort Melissa S. Putman
collection DOAJ
description Both cystic fibrosis (CF) and celiac disease can cause low bone mineral density (BMD) and fractures. Celiac disease may occur at a higher frequency in patients with CF than the general population, and symptoms of these conditions may overlap. We report on two patients presenting with CF-related bone disease in the past year who were subsequently found to have concurrent celiac disease. Because adherence to a gluten-free diet may improve BMD in patients with celiac disease, this could have important implications for treatment. Clinicians should consider screening for celiac disease in patients with CF who have low BMD, worsening BMD in the absence of other risk factors, and/or difficult to treat vitamin D deficiency.
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spelling doaj-art-5f571a88d9304777a00a8d50b87c0d662025-02-03T01:32:39ZengWileyCase Reports in Endocrinology2090-65012090-651X2017-01-01201710.1155/2017/26524032652403Celiac Disease in Patients with Cystic Fibrosis-Related Bone DiseaseMelissa S. Putman0Alexandra Haagensen1Isabel Neuringer2Leonard Sicilian3Division of Endocrinology, Boston Children’s Hospital, Boston, MA, USADivision of Endocrinology, Boston Children’s Hospital, Boston, MA, USAPulmonary Division, Department of Medicine, Massachusetts General Hospital, Boston, MA, USAPulmonary Division, Department of Medicine, Massachusetts General Hospital, Boston, MA, USABoth cystic fibrosis (CF) and celiac disease can cause low bone mineral density (BMD) and fractures. Celiac disease may occur at a higher frequency in patients with CF than the general population, and symptoms of these conditions may overlap. We report on two patients presenting with CF-related bone disease in the past year who were subsequently found to have concurrent celiac disease. Because adherence to a gluten-free diet may improve BMD in patients with celiac disease, this could have important implications for treatment. Clinicians should consider screening for celiac disease in patients with CF who have low BMD, worsening BMD in the absence of other risk factors, and/or difficult to treat vitamin D deficiency.http://dx.doi.org/10.1155/2017/2652403
spellingShingle Melissa S. Putman
Alexandra Haagensen
Isabel Neuringer
Leonard Sicilian
Celiac Disease in Patients with Cystic Fibrosis-Related Bone Disease
Case Reports in Endocrinology
title Celiac Disease in Patients with Cystic Fibrosis-Related Bone Disease
title_full Celiac Disease in Patients with Cystic Fibrosis-Related Bone Disease
title_fullStr Celiac Disease in Patients with Cystic Fibrosis-Related Bone Disease
title_full_unstemmed Celiac Disease in Patients with Cystic Fibrosis-Related Bone Disease
title_short Celiac Disease in Patients with Cystic Fibrosis-Related Bone Disease
title_sort celiac disease in patients with cystic fibrosis related bone disease
url http://dx.doi.org/10.1155/2017/2652403
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AT isabelneuringer celiacdiseaseinpatientswithcysticfibrosisrelatedbonedisease
AT leonardsicilian celiacdiseaseinpatientswithcysticfibrosisrelatedbonedisease