Natural population cohort study on long-lived adults: West China longevity and ageing procedure (WCLAP)
Purpose The West China longevity and ageing procedure (WCLAP) cohort study aims to provide guidance for older adults in western China with the aim of improving quality of life, reducing the burden of family care, summarising the characteristics of longevity lifestyles, building a Chinese-longevity-p...
Saved in:
| Main Authors: | , , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMJ Publishing Group
2022-06-01
|
| Series: | BMJ Open |
| Online Access: | https://bmjopen.bmj.com/content/12/6/e055407.full |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832575369186639872 |
|---|---|
| author | Li Wang Yan Zhang Qiukui Hao Xiaoyan Chen Birong Dong Yan He Meijuan Chen Jirong Yue Xiaochu Wu Tianyao Zhang Yan She Yanling Gao Yiping Deng |
| author_facet | Li Wang Yan Zhang Qiukui Hao Xiaoyan Chen Birong Dong Yan He Meijuan Chen Jirong Yue Xiaochu Wu Tianyao Zhang Yan She Yanling Gao Yiping Deng |
| author_sort | Li Wang |
| collection | DOAJ |
| description | Purpose The West China longevity and ageing procedure (WCLAP) cohort study aims to provide guidance for older adults in western China with the aim of improving quality of life, reducing the burden of family care, summarising the characteristics of longevity lifestyles, building a Chinese-longevity-population biobank and exploring the mechanisms underlying population ageing.Participants Since the establishment of the WCLAP research baseline in 2018, a population of 1537 adults aged 80 years and above, living in the community, have been enrolled in the programme as research participants. Of these, 231 are aged 100 years and above. Participants are followed up every year.Finding to data WCLAP data are collected in five hospital research subcentres strategically located adjacent to the national ‘Longevity Townships’ of Chengdu Ziyang, Leshan, Yibin and Pengshan. Data collection included a comprehensive assessment of the participant’s health (including physical, psychological, social and common chronic disease assessments), instrumental tests (body composition and muscle percentage) and the collection of biomedical-biobank samples (include blood, urine, faeces, hair and urine).Future plans Through the annual cohort follow-up, survival-related information is collected at a group level. Analysis of biological samples facilitates biological characterisation at the microscopic level through proteomics, metabolomics, genomics and other techniques. Baseline data, group-level follow-up data and microbiological examination data are integrated together to provide an evaluation tool, exploring sarcopenia, disability, dementia, caregiver burden, ageing biomarkers and other influencing factors.Trial registration numbers 2018-463; ChiCTR1900020754. |
| format | Article |
| id | doaj-art-5f4636f758e04466acb6da1562a6ae44 |
| institution | Kabale University |
| issn | 2044-6055 |
| language | English |
| publishDate | 2022-06-01 |
| publisher | BMJ Publishing Group |
| record_format | Article |
| series | BMJ Open |
| spelling | doaj-art-5f4636f758e04466acb6da1562a6ae442025-02-01T09:40:08ZengBMJ Publishing GroupBMJ Open2044-60552022-06-0112610.1136/bmjopen-2021-055407Natural population cohort study on long-lived adults: West China longevity and ageing procedure (WCLAP)Li Wang0Yan Zhang1Qiukui Hao2Xiaoyan Chen3Birong Dong4Yan He5Meijuan Chen6Jirong Yue7Xiaochu Wu8Tianyao Zhang9Yan She10Yanling Gao11Yiping Deng121ArsenalBio, Oakland, CA, USADepartment of Obstetrics and Gynecology, Peking University First Hospital, Beijing, ChinaSchool of Rehabilitation Science, McMaster University, Hamilton, Ontario, CanadaNational Clinical Research Center for Geriatrics (WCHSCU), Sichuan University West China Hospital, Chengdu, Sichuan, ChinaSichuan University West China Hospital National Clinical Research Center for Geriatrics, Chengdu, Sichuan, ChinaDepartment of Epidemiology and Health Statistics, School of Public Health, Capital Medical University, Beijing, ChinaPeople`s Hospital of Leshan, Leshan, Sichuan, ChinaDepartment of Geriatrics, West China Hospital of Sichuan University, Chengdu, Sichuan, ChinaNational Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, ChinaThe No.1 Affiliated Hospital of Chengdu Medical College, Chengdu, Sichuan, ChinaMei Shan Shi Peng Shan Qu Chinses Medicine Hospital, Meishan City, Sichuan, ChinaSichuan University West China Hospital of Yibin Hospital, Yibin, Sichuan, ChinaNational Clinical Research Center for Geriatrics (WCHSCU), Sichuan University West China Hospital, Chengdu, Sichuan, ChinaPurpose The West China longevity and ageing procedure (WCLAP) cohort study aims to provide guidance for older adults in western China with the aim of improving quality of life, reducing the burden of family care, summarising the characteristics of longevity lifestyles, building a Chinese-longevity-population biobank and exploring the mechanisms underlying population ageing.Participants Since the establishment of the WCLAP research baseline in 2018, a population of 1537 adults aged 80 years and above, living in the community, have been enrolled in the programme as research participants. Of these, 231 are aged 100 years and above. Participants are followed up every year.Finding to data WCLAP data are collected in five hospital research subcentres strategically located adjacent to the national ‘Longevity Townships’ of Chengdu Ziyang, Leshan, Yibin and Pengshan. Data collection included a comprehensive assessment of the participant’s health (including physical, psychological, social and common chronic disease assessments), instrumental tests (body composition and muscle percentage) and the collection of biomedical-biobank samples (include blood, urine, faeces, hair and urine).Future plans Through the annual cohort follow-up, survival-related information is collected at a group level. Analysis of biological samples facilitates biological characterisation at the microscopic level through proteomics, metabolomics, genomics and other techniques. Baseline data, group-level follow-up data and microbiological examination data are integrated together to provide an evaluation tool, exploring sarcopenia, disability, dementia, caregiver burden, ageing biomarkers and other influencing factors.Trial registration numbers 2018-463; ChiCTR1900020754.https://bmjopen.bmj.com/content/12/6/e055407.full |
| spellingShingle | Li Wang Yan Zhang Qiukui Hao Xiaoyan Chen Birong Dong Yan He Meijuan Chen Jirong Yue Xiaochu Wu Tianyao Zhang Yan She Yanling Gao Yiping Deng Natural population cohort study on long-lived adults: West China longevity and ageing procedure (WCLAP) BMJ Open |
| title | Natural population cohort study on long-lived adults: West China longevity and ageing procedure (WCLAP) |
| title_full | Natural population cohort study on long-lived adults: West China longevity and ageing procedure (WCLAP) |
| title_fullStr | Natural population cohort study on long-lived adults: West China longevity and ageing procedure (WCLAP) |
| title_full_unstemmed | Natural population cohort study on long-lived adults: West China longevity and ageing procedure (WCLAP) |
| title_short | Natural population cohort study on long-lived adults: West China longevity and ageing procedure (WCLAP) |
| title_sort | natural population cohort study on long lived adults west china longevity and ageing procedure wclap |
| url | https://bmjopen.bmj.com/content/12/6/e055407.full |
| work_keys_str_mv | AT liwang naturalpopulationcohortstudyonlonglivedadultswestchinalongevityandageingprocedurewclap AT yanzhang naturalpopulationcohortstudyonlonglivedadultswestchinalongevityandageingprocedurewclap AT qiukuihao naturalpopulationcohortstudyonlonglivedadultswestchinalongevityandageingprocedurewclap AT xiaoyanchen naturalpopulationcohortstudyonlonglivedadultswestchinalongevityandageingprocedurewclap AT birongdong naturalpopulationcohortstudyonlonglivedadultswestchinalongevityandageingprocedurewclap AT yanhe naturalpopulationcohortstudyonlonglivedadultswestchinalongevityandageingprocedurewclap AT meijuanchen naturalpopulationcohortstudyonlonglivedadultswestchinalongevityandageingprocedurewclap AT jirongyue naturalpopulationcohortstudyonlonglivedadultswestchinalongevityandageingprocedurewclap AT xiaochuwu naturalpopulationcohortstudyonlonglivedadultswestchinalongevityandageingprocedurewclap AT tianyaozhang naturalpopulationcohortstudyonlonglivedadultswestchinalongevityandageingprocedurewclap AT yanshe naturalpopulationcohortstudyonlonglivedadultswestchinalongevityandageingprocedurewclap AT yanlinggao naturalpopulationcohortstudyonlonglivedadultswestchinalongevityandageingprocedurewclap AT yipingdeng naturalpopulationcohortstudyonlonglivedadultswestchinalongevityandageingprocedurewclap |