Efficient chimeric mouse production using a novel embryonic stem cell line

Efficient chimeric mouse production using a novel embryonic stem cell line

Embryonic stem cells are commonly used for generation of transgenic mice. Embryonic stem cells could participate in the development of chimeric animals after injection into a blastocyst. Injection of genetically modified embryonic stem cells could lead to germ line transmission of a transgene or gen...

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Bibliographic Details
Main Authors: G. V. Kontsevaya, N. A. Feofanova, A. G. Menzorov, I. E. Pristyazhnyuk, A. V. Smirnov, N. R. Battulin, L. A. Gerlinskaya
Format: Article
Language:English
Published: Siberian Branch of the Russian Academy of Sciences, Federal Research Center Institute of Cytology and Genetics, The Vavilov Society of Geneticists and Breeders 2017-02-01
Series:Вавиловский журнал генетики и селекции
Subjects:
embryonic stem cells
chimeric mice
pluripotency
transgenesis
Online Access:https://vavilov.elpub.ru/jour/article/view/873
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