Adrenal Rest Tumor of the Liver Preoperatively Diagnosed as Hepatocellular Carcinoma

Background. Hepatic adrenal rest tumors are rare and show similar findings to hepatocellular carcinoma (HCC). It is difficult to distinguish an adrenal rest tumor from HCC due to radiological similarity. We report a case of an adrenal rest tumor in the liver that mimicked HCC radiologically. Case Pr...

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Main Authors: Megumu Enjoji, Katsuya Sanada, Ryota Seki, Takashi Ito, Masato Maeda
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:Case Reports in Surgery
Online Access:http://dx.doi.org/10.1155/2017/8231943
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author Megumu Enjoji
Katsuya Sanada
Ryota Seki
Takashi Ito
Masato Maeda
author_facet Megumu Enjoji
Katsuya Sanada
Ryota Seki
Takashi Ito
Masato Maeda
author_sort Megumu Enjoji
collection DOAJ
description Background. Hepatic adrenal rest tumors are rare and show similar findings to hepatocellular carcinoma (HCC). It is difficult to distinguish an adrenal rest tumor from HCC due to radiological similarity. We report a case of an adrenal rest tumor in the liver that mimicked HCC radiologically. Case Presentation. A 67-year-old female was referred to our hospital due to the finding of a hepatic mass. Enhanced computed tomography revealed a 17 mm well-defined tumor that was enhanced in the arterial phase and washed out in the portal and delayed phase in the posterosuperior subsegment of the right hepatic lobe, and HCC was suspected. We performed a subsegmental resection of the liver. Microscopic findings showed that the tumor was composed of pale cells, and tumor cells were aligned in alveolar or fascicular arrangements in a similar manner to features of adrenocortical tissue. Immunohistochemically, the tumor expressed synaptophysin and CD56. The final histopathologic diagnosis in this case was an adrenal rest tumor of the liver. Conclusions. An adrenal rest tumor is similar to HCC in radiological findings. This hepatic tumor should be added to the list of radiological differential diagnoses of hypervascular hepatic tumors.
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spelling doaj-art-5efe33513f214614a636433dbe228d5d2025-02-03T01:32:07ZengWileyCase Reports in Surgery2090-69002090-69192017-01-01201710.1155/2017/82319438231943Adrenal Rest Tumor of the Liver Preoperatively Diagnosed as Hepatocellular CarcinomaMegumu Enjoji0Katsuya Sanada1Ryota Seki2Takashi Ito3Masato Maeda4Department of Surgery, Mishima General Hospital, 2276 Yata, Mishima, Shizuoka 411-0801, JapanDepartment of Surgery, Mishima General Hospital, 2276 Yata, Mishima, Shizuoka 411-0801, JapanDepartment of Surgery, Mishima General Hospital, 2276 Yata, Mishima, Shizuoka 411-0801, JapanDepartment of Human Pathology, Tokyo Medical and Dental University Graduate School, 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8519, JapanDepartment of Gastrointestinal Medicine, Mishima General Hospital, 2276 Yata, Mishima, Shizuoka 411-0801, JapanBackground. Hepatic adrenal rest tumors are rare and show similar findings to hepatocellular carcinoma (HCC). It is difficult to distinguish an adrenal rest tumor from HCC due to radiological similarity. We report a case of an adrenal rest tumor in the liver that mimicked HCC radiologically. Case Presentation. A 67-year-old female was referred to our hospital due to the finding of a hepatic mass. Enhanced computed tomography revealed a 17 mm well-defined tumor that was enhanced in the arterial phase and washed out in the portal and delayed phase in the posterosuperior subsegment of the right hepatic lobe, and HCC was suspected. We performed a subsegmental resection of the liver. Microscopic findings showed that the tumor was composed of pale cells, and tumor cells were aligned in alveolar or fascicular arrangements in a similar manner to features of adrenocortical tissue. Immunohistochemically, the tumor expressed synaptophysin and CD56. The final histopathologic diagnosis in this case was an adrenal rest tumor of the liver. Conclusions. An adrenal rest tumor is similar to HCC in radiological findings. This hepatic tumor should be added to the list of radiological differential diagnoses of hypervascular hepatic tumors.http://dx.doi.org/10.1155/2017/8231943
spellingShingle Megumu Enjoji
Katsuya Sanada
Ryota Seki
Takashi Ito
Masato Maeda
Adrenal Rest Tumor of the Liver Preoperatively Diagnosed as Hepatocellular Carcinoma
Case Reports in Surgery
title Adrenal Rest Tumor of the Liver Preoperatively Diagnosed as Hepatocellular Carcinoma
title_full Adrenal Rest Tumor of the Liver Preoperatively Diagnosed as Hepatocellular Carcinoma
title_fullStr Adrenal Rest Tumor of the Liver Preoperatively Diagnosed as Hepatocellular Carcinoma
title_full_unstemmed Adrenal Rest Tumor of the Liver Preoperatively Diagnosed as Hepatocellular Carcinoma
title_short Adrenal Rest Tumor of the Liver Preoperatively Diagnosed as Hepatocellular Carcinoma
title_sort adrenal rest tumor of the liver preoperatively diagnosed as hepatocellular carcinoma
url http://dx.doi.org/10.1155/2017/8231943
work_keys_str_mv AT megumuenjoji adrenalresttumoroftheliverpreoperativelydiagnosedashepatocellularcarcinoma
AT katsuyasanada adrenalresttumoroftheliverpreoperativelydiagnosedashepatocellularcarcinoma
AT ryotaseki adrenalresttumoroftheliverpreoperativelydiagnosedashepatocellularcarcinoma
AT takashiito adrenalresttumoroftheliverpreoperativelydiagnosedashepatocellularcarcinoma
AT masatomaeda adrenalresttumoroftheliverpreoperativelydiagnosedashepatocellularcarcinoma