Bariatric Surgery, Polycystic Ovary Syndrome, and Infertility
Background. Polycystic ovary syndrome (PCOS) is the commonest cause of female infertility. Visceral obesity and insulin resistance are key pathophysiological mechanisms behind PCOS. Women suffering from this syndrome and infertility often seek bariatric surgery hoping that they would be able to conc...
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | Journal of Obesity |
| Online Access: | http://dx.doi.org/10.1155/2016/1871594 |
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| _version_ | 1832556612024270848 |
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| author | James Butterworth Jean Deguara Cynthia-Michelle Borg |
| author_facet | James Butterworth Jean Deguara Cynthia-Michelle Borg |
| author_sort | James Butterworth |
| collection | DOAJ |
| description | Background. Polycystic ovary syndrome (PCOS) is the commonest cause of female infertility. Visceral obesity and insulin resistance are key pathophysiological mechanisms behind PCOS. Women suffering from this syndrome and infertility often seek bariatric surgery hoping that they would be able to conceive postoperatively. Objective. At present, there is no consensus on the role of bariatric surgery in the management of PCOS-associated infertility within the medical community, making it difficult to give specific advice to these women, so a review of the literature was necessary. Results. A detailed review of the literature was performed. Only 6 manuscripts were relevant and contained quantitative data. They demonstrated that bariatric surgery results in postoperative conception rates varying from 33% to 100%. Surgery is also associated with amelioration of menstrual irregularities, hormonal abnormalities, and hirsutism that are associated with PCOS. These studies were retrospective and only had a small number of participants with infertility. Conclusions. Bariatric surgery has been shown to conclusively improve life expectancy, quality of life, and comorbidities like type 2 diabetes and obstructive sleep apnea. However, further research is required to identify whether weight loss surgery results in significant improvement in fertility of women with PCOS and to investigate which operation has the best results. |
| format | Article |
| id | doaj-art-5ee8dadc13c1403b9872cf2ea6429663 |
| institution | Kabale University |
| issn | 2090-0708 2090-0716 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Obesity |
| spelling | doaj-art-5ee8dadc13c1403b9872cf2ea64296632025-02-03T05:44:55ZengWileyJournal of Obesity2090-07082090-07162016-01-01201610.1155/2016/18715941871594Bariatric Surgery, Polycystic Ovary Syndrome, and InfertilityJames Butterworth0Jean Deguara1Cynthia-Michelle Borg2University Hospital Lewisham, Lewisham and Greenwich NHS Trust, London, UKKingston Hospital NHS Foundation Trust, Kingston upon Thames, UKUniversity Hospital Lewisham, Lewisham and Greenwich NHS Trust, London, UKBackground. Polycystic ovary syndrome (PCOS) is the commonest cause of female infertility. Visceral obesity and insulin resistance are key pathophysiological mechanisms behind PCOS. Women suffering from this syndrome and infertility often seek bariatric surgery hoping that they would be able to conceive postoperatively. Objective. At present, there is no consensus on the role of bariatric surgery in the management of PCOS-associated infertility within the medical community, making it difficult to give specific advice to these women, so a review of the literature was necessary. Results. A detailed review of the literature was performed. Only 6 manuscripts were relevant and contained quantitative data. They demonstrated that bariatric surgery results in postoperative conception rates varying from 33% to 100%. Surgery is also associated with amelioration of menstrual irregularities, hormonal abnormalities, and hirsutism that are associated with PCOS. These studies were retrospective and only had a small number of participants with infertility. Conclusions. Bariatric surgery has been shown to conclusively improve life expectancy, quality of life, and comorbidities like type 2 diabetes and obstructive sleep apnea. However, further research is required to identify whether weight loss surgery results in significant improvement in fertility of women with PCOS and to investigate which operation has the best results.http://dx.doi.org/10.1155/2016/1871594 |
| spellingShingle | James Butterworth Jean Deguara Cynthia-Michelle Borg Bariatric Surgery, Polycystic Ovary Syndrome, and Infertility Journal of Obesity |
| title | Bariatric Surgery, Polycystic Ovary Syndrome, and Infertility |
| title_full | Bariatric Surgery, Polycystic Ovary Syndrome, and Infertility |
| title_fullStr | Bariatric Surgery, Polycystic Ovary Syndrome, and Infertility |
| title_full_unstemmed | Bariatric Surgery, Polycystic Ovary Syndrome, and Infertility |
| title_short | Bariatric Surgery, Polycystic Ovary Syndrome, and Infertility |
| title_sort | bariatric surgery polycystic ovary syndrome and infertility |
| url | http://dx.doi.org/10.1155/2016/1871594 |
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