Severe Acute Radiation Dermatitis in a Patient with Argyria

Argyria is a rare cutaneous condition due to dermal silver deposition leading to irreversible blue-grey discoloration. Acute radiation dermatitis (RD) is an expected toxicity in patients undergoing radiotherapy but it is unknown to what extent argyria affects the onset and severity of RD. We report...

Full description

Saved in:
Bibliographic Details
Main Authors: P. Gorayski, M. B. Pinkham, J. B. Muir, A. P. Pullar
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:Case Reports in Oncological Medicine
Online Access:http://dx.doi.org/10.1155/2014/154349
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832554835985039360
author P. Gorayski
M. B. Pinkham
J. B. Muir
A. P. Pullar
author_facet P. Gorayski
M. B. Pinkham
J. B. Muir
A. P. Pullar
author_sort P. Gorayski
collection DOAJ
description Argyria is a rare cutaneous condition due to dermal silver deposition leading to irreversible blue-grey discoloration. Acute radiation dermatitis (RD) is an expected toxicity in patients undergoing radiotherapy but it is unknown to what extent argyria affects the onset and severity of RD. We report a patient with argyria treated with concurrent chemoradiotherapy for Merkel cell carcinoma who experienced an unexpectedly brisk and severe RD during treatment. Possible mechanisms for this interaction are considered.
format Article
id doaj-art-5ee3588b5992498cae0ae78f1decdb18
institution Kabale University
issn 2090-6706
2090-6714
language English
publishDate 2014-01-01
publisher Wiley
record_format Article
series Case Reports in Oncological Medicine
spelling doaj-art-5ee3588b5992498cae0ae78f1decdb182025-02-03T05:50:22ZengWileyCase Reports in Oncological Medicine2090-67062090-67142014-01-01201410.1155/2014/154349154349Severe Acute Radiation Dermatitis in a Patient with ArgyriaP. Gorayski0M. B. Pinkham1J. B. Muir2A. P. Pullar3Radiation Oncology, Mater Centre, South Brisbane, QLD 4101, AustraliaRadiation Oncology, Mater Centre, South Brisbane, QLD 4101, AustraliaDepartment of Dermatology, Mater Adults Hospital, South Brisbane, QLD 4101, AustraliaRadiation Oncology, Mater Centre, South Brisbane, QLD 4101, AustraliaArgyria is a rare cutaneous condition due to dermal silver deposition leading to irreversible blue-grey discoloration. Acute radiation dermatitis (RD) is an expected toxicity in patients undergoing radiotherapy but it is unknown to what extent argyria affects the onset and severity of RD. We report a patient with argyria treated with concurrent chemoradiotherapy for Merkel cell carcinoma who experienced an unexpectedly brisk and severe RD during treatment. Possible mechanisms for this interaction are considered.http://dx.doi.org/10.1155/2014/154349
spellingShingle P. Gorayski
M. B. Pinkham
J. B. Muir
A. P. Pullar
Severe Acute Radiation Dermatitis in a Patient with Argyria
Case Reports in Oncological Medicine
title Severe Acute Radiation Dermatitis in a Patient with Argyria
title_full Severe Acute Radiation Dermatitis in a Patient with Argyria
title_fullStr Severe Acute Radiation Dermatitis in a Patient with Argyria
title_full_unstemmed Severe Acute Radiation Dermatitis in a Patient with Argyria
title_short Severe Acute Radiation Dermatitis in a Patient with Argyria
title_sort severe acute radiation dermatitis in a patient with argyria
url http://dx.doi.org/10.1155/2014/154349
work_keys_str_mv AT pgorayski severeacuteradiationdermatitisinapatientwithargyria
AT mbpinkham severeacuteradiationdermatitisinapatientwithargyria
AT jbmuir severeacuteradiationdermatitisinapatientwithargyria
AT appullar severeacuteradiationdermatitisinapatientwithargyria