Severe Acute Radiation Dermatitis in a Patient with Argyria

Argyria is a rare cutaneous condition due to dermal silver deposition leading to irreversible blue-grey discoloration. Acute radiation dermatitis (RD) is an expected toxicity in patients undergoing radiotherapy but it is unknown to what extent argyria affects the onset and severity of RD. We report...

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Bibliographic Details
Main Authors: P. Gorayski, M. B. Pinkham, J. B. Muir, A. P. Pullar
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:Case Reports in Oncological Medicine
Online Access:http://dx.doi.org/10.1155/2014/154349
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Summary:Argyria is a rare cutaneous condition due to dermal silver deposition leading to irreversible blue-grey discoloration. Acute radiation dermatitis (RD) is an expected toxicity in patients undergoing radiotherapy but it is unknown to what extent argyria affects the onset and severity of RD. We report a patient with argyria treated with concurrent chemoradiotherapy for Merkel cell carcinoma who experienced an unexpectedly brisk and severe RD during treatment. Possible mechanisms for this interaction are considered.
ISSN:2090-6706
2090-6714