Pediatric Adrenal Insufficiency: Diagnosis, Management, and New Therapies
Adrenal insufficiency may result from a wide variety of congenital or acquired disorders of hypothalamus, pituitary, or adrenal cortex. Destruction or dysfunction of the adrenal cortex is the cause of primary adrenal insufficiency, while secondary adrenal insufficiency is a result of pituitary or hy...
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | International Journal of Pediatrics |
| Online Access: | http://dx.doi.org/10.1155/2018/1739831 |
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| author | Sasigarn A. Bowden Rohan Henry |
| author_facet | Sasigarn A. Bowden Rohan Henry |
| author_sort | Sasigarn A. Bowden |
| collection | DOAJ |
| description | Adrenal insufficiency may result from a wide variety of congenital or acquired disorders of hypothalamus, pituitary, or adrenal cortex. Destruction or dysfunction of the adrenal cortex is the cause of primary adrenal insufficiency, while secondary adrenal insufficiency is a result of pituitary or hypothalamic disease. Timely diagnosis and clinical management of adrenal insufficiency are critical to prevent morbidity and mortality. This review summarizes the etiologies, presentation, and diagnosis of adrenal insufficiency utilizing different dynamic hormone testing and describes current treatment recommendations and new therapies. |
| format | Article |
| id | doaj-art-5ed01361978440a699397437ea1398ef |
| institution | Kabale University |
| issn | 1687-9740 1687-9759 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Pediatrics |
| spelling | doaj-art-5ed01361978440a699397437ea1398ef2025-02-03T01:09:14ZengWileyInternational Journal of Pediatrics1687-97401687-97592018-01-01201810.1155/2018/17398311739831Pediatric Adrenal Insufficiency: Diagnosis, Management, and New TherapiesSasigarn A. Bowden0Rohan Henry1Division of Endocrinology, Department of Pediatrics, Nationwide Children’s Hospital/The Ohio State University College of Medicine, Columbus, Ohio, USADivision of Endocrinology, Department of Pediatrics, Nationwide Children’s Hospital/The Ohio State University College of Medicine, Columbus, Ohio, USAAdrenal insufficiency may result from a wide variety of congenital or acquired disorders of hypothalamus, pituitary, or adrenal cortex. Destruction or dysfunction of the adrenal cortex is the cause of primary adrenal insufficiency, while secondary adrenal insufficiency is a result of pituitary or hypothalamic disease. Timely diagnosis and clinical management of adrenal insufficiency are critical to prevent morbidity and mortality. This review summarizes the etiologies, presentation, and diagnosis of adrenal insufficiency utilizing different dynamic hormone testing and describes current treatment recommendations and new therapies.http://dx.doi.org/10.1155/2018/1739831 |
| spellingShingle | Sasigarn A. Bowden Rohan Henry Pediatric Adrenal Insufficiency: Diagnosis, Management, and New Therapies International Journal of Pediatrics |
| title | Pediatric Adrenal Insufficiency: Diagnosis, Management, and New Therapies |
| title_full | Pediatric Adrenal Insufficiency: Diagnosis, Management, and New Therapies |
| title_fullStr | Pediatric Adrenal Insufficiency: Diagnosis, Management, and New Therapies |
| title_full_unstemmed | Pediatric Adrenal Insufficiency: Diagnosis, Management, and New Therapies |
| title_short | Pediatric Adrenal Insufficiency: Diagnosis, Management, and New Therapies |
| title_sort | pediatric adrenal insufficiency diagnosis management and new therapies |
| url | http://dx.doi.org/10.1155/2018/1739831 |
| work_keys_str_mv | AT sasigarnabowden pediatricadrenalinsufficiencydiagnosismanagementandnewtherapies AT rohanhenry pediatricadrenalinsufficiencydiagnosismanagementandnewtherapies |