Discovering Associations: Kawasaki Disease and COVID-19

The COVID-19 pandemic has resulted in over 3.6 million confirmed cases and over 254,000 deaths worldwide. It has been theorized that children who are asymptomatic or who do not display significant respiratory symptoms are potential vectors for community transmission of the SARS-CoV-2 virus. This is...

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Main Authors: Nicholas Peterson, Kaustubh Sagdeo, Donna Tyungu, Cristin Harper, Kyle Mihaylo, Elza Pollak-Christian
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Case Reports in Pediatrics
Online Access:http://dx.doi.org/10.1155/2020/8880242
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author Nicholas Peterson
Kaustubh Sagdeo
Donna Tyungu
Cristin Harper
Kyle Mihaylo
Elza Pollak-Christian
author_facet Nicholas Peterson
Kaustubh Sagdeo
Donna Tyungu
Cristin Harper
Kyle Mihaylo
Elza Pollak-Christian
author_sort Nicholas Peterson
collection DOAJ
description The COVID-19 pandemic has resulted in over 3.6 million confirmed cases and over 254,000 deaths worldwide. It has been theorized that children who are asymptomatic or who do not display significant respiratory symptoms are potential vectors for community transmission of the SARS-CoV-2 virus. This is incompletely understood due to the current lack of widespread testing in the pediatric population. We describe a case of a 2-year-old female who presented with symptoms of prolonged fever, conjunctivitis, extremity edema, rash, dry/cracked lips, fussiness and fatigue, and a notable absence of respiratory symptoms. She was diagnosed with and treated for Kawasaki disease. Due to her prolonged fever, she was tested for COVID-19 which was positive; however, she did not develop respiratory symptoms during her illness. At the time of manuscript submission, this is the second case report to our knowledge showing an association between Kawasaki Disease and SARS-CoV-2 virus, both of which are poorly understood diseases in the pediatric population. This case highlights the value of testing pediatric patients for COVID-19 who present with fever in the absence of other symptoms to improve epidemiologic measures during the ongoing pandemic, and it also adds to a foundation of cases for future research on the presence of a link between Kawasaki Disease and COVID-19.
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spelling doaj-art-5eb6844f017e43a089889961e3bd62c22025-02-03T06:46:54ZengWileyCase Reports in Pediatrics2090-68032090-68112020-01-01202010.1155/2020/88802428880242Discovering Associations: Kawasaki Disease and COVID-19Nicholas Peterson0Kaustubh Sagdeo1Donna Tyungu2Cristin Harper3Kyle Mihaylo4Elza Pollak-Christian5The University of Oklahoma Health Sciences Center, Department of Pediatrics, Section of Pediatric Hospital Medicine, Oklahoma City, OK 73104, USAThe University of Oklahoma Health Sciences Center, Department of Pediatrics, Section of Pediatric Hospital Medicine, Oklahoma City, OK 73104, USAThe University of Oklahoma Health Sciences Center, Department of Pediatrics, Section of Pediatric Hospital Medicine, Oklahoma City, OK 73104, USAThe University of Oklahoma Health Sciences Center, Department of Pediatrics, Pediatric Resident, Oklahoma City, OK 73104, USAThe University of Oklahoma Health Sciences Center, Department of Pediatrics, Pediatric Resident, Oklahoma City, OK 73104, USAThe University of Oklahoma Health Sciences Center, Department of Pediatrics, Section of Pediatric Hospital Medicine, Oklahoma City, OK 73104, USAThe COVID-19 pandemic has resulted in over 3.6 million confirmed cases and over 254,000 deaths worldwide. It has been theorized that children who are asymptomatic or who do not display significant respiratory symptoms are potential vectors for community transmission of the SARS-CoV-2 virus. This is incompletely understood due to the current lack of widespread testing in the pediatric population. We describe a case of a 2-year-old female who presented with symptoms of prolonged fever, conjunctivitis, extremity edema, rash, dry/cracked lips, fussiness and fatigue, and a notable absence of respiratory symptoms. She was diagnosed with and treated for Kawasaki disease. Due to her prolonged fever, she was tested for COVID-19 which was positive; however, she did not develop respiratory symptoms during her illness. At the time of manuscript submission, this is the second case report to our knowledge showing an association between Kawasaki Disease and SARS-CoV-2 virus, both of which are poorly understood diseases in the pediatric population. This case highlights the value of testing pediatric patients for COVID-19 who present with fever in the absence of other symptoms to improve epidemiologic measures during the ongoing pandemic, and it also adds to a foundation of cases for future research on the presence of a link between Kawasaki Disease and COVID-19.http://dx.doi.org/10.1155/2020/8880242
spellingShingle Nicholas Peterson
Kaustubh Sagdeo
Donna Tyungu
Cristin Harper
Kyle Mihaylo
Elza Pollak-Christian
Discovering Associations: Kawasaki Disease and COVID-19
Case Reports in Pediatrics
title Discovering Associations: Kawasaki Disease and COVID-19
title_full Discovering Associations: Kawasaki Disease and COVID-19
title_fullStr Discovering Associations: Kawasaki Disease and COVID-19
title_full_unstemmed Discovering Associations: Kawasaki Disease and COVID-19
title_short Discovering Associations: Kawasaki Disease and COVID-19
title_sort discovering associations kawasaki disease and covid 19
url http://dx.doi.org/10.1155/2020/8880242
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