Comparison between manual and automated methods for the isolation of mononuclear cells and mesenchymal stem cells using ficoll: efficacy and reproducibility

Comparison between manual and automated methods for the isolation of mononuclear cells and mesenchymal stem cells using ficoll: efficacy and reproducibility

Mesenchymal stem cells (MSCs), hold immense therapeutic promise in Advanced Therapy Medicinal Products (ATMPs) due to their multipotent nature, immunomodulatory properties, and anti-inflammatory effects. However, a significant challenge lies in obtaining sufficient quantities of MSCs for therapeutic...

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Bibliographic Details
Main Authors: Ester Moñivas, Concepción Aguayo, Silvia de la Calle, Paula Martínez, Nieves Repollés, Mercedes Zurita
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
bone marrow
mononuclear cells
mesenchymal stem cells
ficoll
sepax
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2025.1556697/full
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