Identification of Differentially Expressed Genes from Ovarian Cancer Cells by MICROMAX™ cDNA Microarray System

Using the MICROMAX™ cDNA microarray system, we were able to identify genes that are differentially overexpressed in ovarian cancer. A total of 30 putative genes, which are differentially overexpressed in ovarian cancer cell lines, were identified. The differential expression of some of these genes w...

Full description

Saved in:
Bibliographic Details
Main Authors: Kwong-Kwok Wong, Rita S. Cheng, Samuel C. Mok
Format: Article
Language:English
Published: Taylor & Francis Group 2001-03-01
Series:BioTechniques
Online Access:https://www.future-science.com/doi/10.2144/01303dd05
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Using the MICROMAX™ cDNA microarray system, we were able to identify genes that are differentially overexpressed in ovarian cancer. A total of 30 putative genes, which are differentially overexpressed in ovarian cancer cell lines, were identified. The differential expression of some of these genes was further confirmed by real-time RT-PCR. Using this strategy, we have identified genes that either overexpress in all cancer cell lines or in only some cancer cell lines. Further characterization of these genes will allow them to be exploited in diagnosis, prognosis, anticancer therapy, and molecular classification of ovarian cancer.
ISSN:0736-6205
1940-9818