Development of a UPLC-MS/MS method for the determination of sulfatinib and its no interaction with myricetin in rats

Development of a UPLC-MS/MS method for the determination of sulfatinib and its no interaction with myricetin in rats

IntroductionSulfatinib is a novel oral tyrosine kinase inhibitor (TKI) with selective inhibition of fibroblast growth factor (FGFR), colony-stimulating factor 1 receptor (CSF-1R) and vascular endothelial growth factor receptor (VEGFR) 1, 2, and 3. It has been approved for the therapy of neuroendocri...

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Bibliographic Details
Main Authors: Dongxin Chen, Jie Chen, Hailun Xia, Xiaohai Chen, Jinyu Hu, Guangliang Wu, Xuegu Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Pharmacology
Subjects:
sulfatinib
myricetin
drug-drug interaction
pharmacokinetics
UPLC-MS/MS
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2024.1498339/full
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